PIPA580065

SPHK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA580065-Each-of-1 In Stock ₹ 38,844.24

PIPA580065 - Each of 1

₹ 38,844.24

In Stock

Quantity

1

Base Price: ₹ 38,844.24

GST (18%): ₹ 6,991.963

Total Price: ₹ 45,836.203

Antigen

SPHK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Sphk2

Gene Alias

C76851; SK 2; SK2; SK-2; Sphingosine kinase 2; sphingosine kinase type 2; Sphk2; SPK 2; SPK-2; Spk2, Sk2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

308589, 56632, 56848

Content And Storage

-20°C

Form

Lyophilized

Applications

Flow Cytometry, Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

Q9JIA7, Q9NRA0

Gene Symbols

Sphk2

Immunogen

E. coli-derived human SPHK2 recombinant protein (Position: F215-M269).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • SPHK2, along with SPHK1, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P)
  • S1P signals through G-protein coupled receptors and controls diverse cellular processes
  • Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer
  • SPHK2 is an important signaling molecule with intra- and extracellular functions and has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis
  • The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors)
  • These receptors couple to multiple G proteins (e.g
  • S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide raange of cellular events including cell motility, survival, apoptosis, migration and cell-cell interaction
  • Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells
  • S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).

Compare Similar Items

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Img

Thermo Scientific

PIPA580065

--


Antigen:
SPHK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Sphk2

Gene Alias:
C76851; SK 2; SK2; SK-2; Sphingosine kinase 2; sphingosine kinase type 2; Sphk2; SPK 2; SPK-2; Spk2, Sk2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
308589, 56632, 56848

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q9JIA7, Q9NRA0

Gene Symbols:
Sphk2

Immunogen:
E. coli-derived human SPHK2 recombinant protein (Position: F215-M269).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA580067

--


Antigen:
CD43

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPN

Gene Alias:
3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20737, 24796, 6693

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P13838, P15702, P16150

Gene Symbols:
SPN

Immunogen:
E.coli-derived human CD43 recombinant protein (Position: A272-P400).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA580068

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Antigen:
SPR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPR

Gene Alias:
AA409688; ENSMUSG00000071345; Gm10328; SDR38C1; sepiapterin reductase; sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase); short chain dehydrogenase/reductase family 38C, member 1; SPR

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20751, 6697

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P35270, Q64105

Gene Symbols:
SPR

Immunogen:
E. coli-derived human SPR recombinant protein (Position: V36-K261).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA580069

--


Antigen:
SRSF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SRSF1

Gene Alias:
1110054N12Rik; 5730507C05Rik; 6330415C05Rik; AI482334; Alternative-splicing factor 1; ASF; ASF/SF2; ASF-1; AW491331; OK/SW-cl.3; pre-mRNA-splicing factor SF2, P33 subunit; pre-mRNA-splicing factor SRp30a; serine and arginine rich splicing factor 1; serine/arginine-rich splicing factor 1; SF2; SF2p33; SFRS1; splicing factor 2; splicing factor, arginine/serine-rich 1; splicing factor, arginine/serine-rich 1 (ASF/SF2); splicing factor, arginine/serine-rich 1B; splicing factor, arginine/serine-rich, 30-KD, A; SR splicing factor 1; SRp30a; Srsf1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110809, 6426, 689890

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q07955, Q6PDM2

Gene Symbols:
SRSF1

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of Human SF2 (6-33aa VIRGPAGNNDCRIYVGNLPPDIRTKDIE).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG