PIPA580210
USP7 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA580210-Each-of-1 | In Stock | ₹ 38,844.24 |
PIPA580210 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,844.24
GST (18%): ₹ 6,991.963
Total Price: ₹ 45,836.203
Antigen
USP7
Classification
Polyclonal
Conjugate
Unconjugated
Gene
USP7
Gene Alias
2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
252870, 360471, 7874
Content And Storage
-20°C
Form
Lyophilized
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.
Q4VSI4, Q6A4J8, Q93009
Gene Symbols
USP7
Immunogen
E. coli-derived human HAUSP/USP7 recombinant protein (Position: L258-D483).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- USP7 or HAUSP is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates
- Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, HAUSP activity generally stabilizes its substrate proteins
- HAUSP is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53
- Normally, p53 levels are kept low in part due to Mdm2-mediated ubiquitylation and degradation of p53
- Interestingly, in response to oncogenic insults, HAUSP can deubiquitinate p53 and protect p53 from Mdm2-mediated degradation, indicating that it may possess a tumor suppressor function for the immediate stabilization of p53 in response to stress
- Another important role of HAUSP function involves the oncogenic stabilization of p53
- Oncogenes such as Myc and E1A are thought to activate p53 through a p19 alternative reading frame (p19ARF, also called ARF)-dependent pathway, although some evidence suggests ARF is not essential in this process
- An intriguing possibility is that HAUSP provides an alternative pathway for safeguarding the cell against oncogenic insults.
Compare Similar Items
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Antigen: USP7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: USP7
Gene Alias: 2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 252870, 360471, 7874
Content And Storage: -20°C
Form: Lyophilized
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: Q4VSI4, Q6A4J8, Q93009
Gene Symbols: USP7
Immunogen: E. coli-derived human HAUSP/USP7 recombinant protein (Position: L258-D483).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
USP7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
USP7
Gene Alias:
2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
252870, 360471, 7874
Content And Storage:
-20°C
Form:
Lyophilized
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
Q4VSI4, Q6A4J8, Q93009
Gene Symbols:
USP7
Immunogen:
E. coli-derived human HAUSP/USP7 recombinant protein (Position: L258-D483).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: VCAM-1 (CD106)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: VCAM1
Gene Alias: adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; Vcam1; Vcam-1; VCAM1B
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22329, 25361
Content And Storage: -20°C
Form: Lyophilized
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: P29533, P29534
Gene Symbols: VCAM1
Immunogen: E. coli-derived mouse VCAM1 recombinant protein (Position: F25-L270).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
VCAM-1 (CD106)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
VCAM1
Gene Alias:
adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; Vcam1; Vcam-1; VCAM1B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22329, 25361
Content And Storage:
-20°C
Form:
Lyophilized
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
P29533, P29534
Gene Symbols:
VCAM1
Immunogen:
E. coli-derived mouse VCAM1 recombinant protein (Position: F25-L270).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Vinculin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: VCL
Gene Alias: 9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; metavinculin; meta-vinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; unnamed protein product; Vcl; vcl {ECO:0000250; VIN; vinc; vinc 1; VINC1; Vinculin; vinculin {ECO:0000250
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22330, 7414
Content And Storage: -20°C
Form: Lyophilized
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.: P18206, Q64727
Gene Symbols: VCL
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Vinculin (173-188aa KMIDERQQELTHQEHR).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Vinculin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
VCL
Gene Alias:
9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; metavinculin; meta-vinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; unnamed protein product; Vcl; vcl {ECO:0000250; VIN; vinc; vinc 1; VINC1; Vinculin; vinculin {ECO:0000250
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22330, 7414
Content And Storage:
-20°C
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.:
P18206, Q64727
Gene Symbols:
VCL
Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human Vinculin (173-188aa KMIDERQQELTHQEHR).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: VCP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: VCP
Gene Alias: 15S Mg(2+)-ATPase p97 subunit; 3110001E05; AAA ATPase p97; ALS14; CDC48; cell division cycle gene CDC48; CMT2Y; epididymis luminal protein 220; epididymis secretory protein Li 70; HEL-220; HEL-S-70; homolog of yeast cdc48; IBMPFD; IBMPFD1; Inv protein; or HEL-S-70; p97; p97 atpase; p97/VCP; Protein CDC48; si:ch211-113n10.2; TER ATPase; TERA; transitional endoplasmic reticulum ATPase; valosin containing protein; valosin-containing protein; Vcp; wu:fd16d05; wu:fj63d11; yeast Cdc48p homolog
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116643, 269523, 7415
Content And Storage: -20°C
Form: Lyophilized
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.: P46462, P55072, Q01853
Gene Symbols: VCP
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human VCP (749-766aa DNDIRKYEMFAQTLQQSR).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
VCP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
VCP
Gene Alias:
15S Mg(2+)-ATPase p97 subunit; 3110001E05; AAA ATPase p97; ALS14; CDC48; cell division cycle gene CDC48; CMT2Y; epididymis luminal protein 220; epididymis secretory protein Li 70; HEL-220; HEL-S-70; homolog of yeast cdc48; IBMPFD; IBMPFD1; Inv protein; or HEL-S-70; p97; p97 atpase; p97/VCP; Protein CDC48; si:ch211-113n10.2; TER ATPase; TERA; transitional endoplasmic reticulum ATPase; valosin containing protein; valosin-containing protein; Vcp; wu:fd16d05; wu:fj63d11; yeast Cdc48p homolog
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116643, 269523, 7415
Content And Storage:
-20°C
Form:
Lyophilized
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.:
P46462, P55072, Q01853
Gene Symbols:
VCP
Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human VCP (749-766aa DNDIRKYEMFAQTLQQSR).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG