PIPA580673
NLK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA580673-Each-of-1 | In Stock | ₹ 30,801.60 |
PIPA580673 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,801.60
GST (18%): ₹ 5,544.288
Total Price: ₹ 36,345.888
Antigen
NLK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NLK
Gene Alias
AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
51701
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Western Blot
Concentration
1.0 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q9UBE8
Gene Symbols
NLK
Immunogen
Recombinant Human nemo-like kinase protein (Val121-Glu527)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- This antibody has specificity for Human nemo-like kinase
- NLK is a serine/threonine kinase involved in signal transduction and cellular communication
- Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2
- Activation of this pathway causes binding to and phosphorylation of the histone methyltransferase SETDB1
- The NLK-SETDB1 complex subsequently interacts with PPARG, leading to methylation of PPARG target promoters at histone H3K9 and transcriptional silencing
- The resulting loss of PPARG target gene transcription inhibits adipogenesis and promotes osteoblastogenesis in mesenchymal stem cells (MSCs)
- Negative regulator of the canonical Wnt/beta-catenin signaling pathway
- Binds to and phosphorylates TCF7L2/TCF4 and LEF1, promoting the dissociation of the TCF7L2/LEF1/beta-catenin complex from DNA, as well as the ubiquitination and subsequent proteolysis of LEF1
- Together these effects inhibit the transcriptional activation of canonical Wnt/beta-catenin target genes
- Negative regulator of the Notch signaling pathway
- Binds to and phosphorylates NOTCH1, thereby preventing the formation of a transcriptionally active ternary complex of NOTCH1, RBPJ/RBPSUH and MAML1
- Negative regulator of the MYB family of transcription factors.
Compare Similar Items
Show Difference
Antigen: NLK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NLK
Gene Alias: AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 51701
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Western Blot
Concentration: 1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q9UBE8
Gene Symbols: NLK
Immunogen: Recombinant Human nemo-like kinase protein (Val121-Glu527)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NLK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NLK
Gene Alias:
AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
51701
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Western Blot
Concentration:
1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q9UBE8
Gene Symbols:
NLK
Immunogen:
Recombinant Human nemo-like kinase protein (Val121-Glu527)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: GPX1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GPX1
Gene Alias: AI195024; AL033363; Cellular glutathione peroxidase; CGPx; cytosolic glutathione peroxidase; glutathione peroxidase; glutathione peroxidase 1; Gpx; Gpx1; GPx-1; GPXD; GSHPx; GSHPX1; GSHPx-1; HGNC:4553; MGC14399; MGC88245; OTTHUMP00000210766; Selenium-dependent glutathione peroxidase 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2876
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P07203
Gene Symbols: GPX1
Immunogen: A synthetic peptide corresponding to the C-terminus of the human GPX1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GPX1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GPX1
Gene Alias:
AI195024; AL033363; Cellular glutathione peroxidase; CGPx; cytosolic glutathione peroxidase; glutathione peroxidase; glutathione peroxidase 1; Gpx; Gpx1; GPx-1; GPXD; GSHPx; GSHPX1; GSHPx-1; HGNC:4553; MGC14399; MGC88245; OTTHUMP00000210766; Selenium-dependent glutathione peroxidase 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2876
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P07203
Gene Symbols:
GPX1
Immunogen:
A synthetic peptide corresponding to the C-terminus of the human GPX1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: GSS
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GSS
Gene Alias: AI314904; Glutathione synthase; glutathione synthetase; GS-A/GS-B; GSH S; GSH synthetase; GSHB; GSHS; GSH-S; GSS; HEL-S-64p; HEL-S-88n; MGC14098; OTTHUMP00000030711
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2937
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 0.03% ProClin 300; pH 7
Gene Accession No.: P48637
Gene Symbols: GSS
Immunogen: A synthetic peptide corresponding to the center region of the Human GSS/Glutathione Synthetase
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GSS
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GSS
Gene Alias:
AI314904; Glutathione synthase; glutathione synthetase; GS-A/GS-B; GSH S; GSH synthetase; GSHB; GSHS; GSH-S; GSS; HEL-S-64p; HEL-S-88n; MGC14098; OTTHUMP00000030711
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2937
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 0.03% ProClin 300; pH 7
Gene Accession No.:
P48637
Gene Symbols:
GSS
Immunogen:
A synthetic peptide corresponding to the center region of the Human GSS/Glutathione Synthetase
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: GSTK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GSTK1
Gene Alias: 0610025I19Rik; AW260476; DsbA-L; glutathione S-transferase class kappa; glutathione S-transferase k1; glutathione S-transferase kappa 1; Glutathione S-transferase subunit 13; glutathione S-transferase subunit 13 homolog; glutathione S-transferase, mitochondrial; GST; GST 13-13; GST class-kappa; GST13; GST13-13; Gstk1; GSTK1-1; GSTkappa; HDCMD47P; hGSTK1; mGSTK1; rGSTK1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 373156
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q9Y2Q3
Gene Symbols: GSTK1
Immunogen: Recombinant Human GSTK1 Protein (Gly2-Leu226)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GSTK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GSTK1
Gene Alias:
0610025I19Rik; AW260476; DsbA-L; glutathione S-transferase class kappa; glutathione S-transferase k1; glutathione S-transferase kappa 1; Glutathione S-transferase subunit 13; glutathione S-transferase subunit 13 homolog; glutathione S-transferase, mitochondrial; GST; GST 13-13; GST class-kappa; GST13; GST13-13; Gstk1; GSTK1-1; GSTkappa; HDCMD47P; hGSTK1; mGSTK1; rGSTK1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
373156
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q9Y2Q3
Gene Symbols:
GSTK1
Immunogen:
Recombinant Human GSTK1 Protein (Gly2-Leu226)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG