PIPA581044

STAT4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA581044-Each-of-1 In Stock ₹ 30,801.60

PIPA581044 - Each of 1

₹ 30,801.60

In Stock

Quantity

1

Base Price: ₹ 30,801.60

GST (18%): ₹ 5,544.288

Total Price: ₹ 36,345.888

Antigen

STAT4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

STAT4

Gene Alias

CIS4; HSPC060; OTTHUMP00000163553; Signal transducer and activator of transcription 4; SLEB11; SOCS4; SOCS6; SSI4; STAI4; STAT; Stat4; STATI4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6775

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q14765

Gene Symbols

STAT4

Immunogen

A synthetic peptide corresponding to the C-terminus of the Human STAT4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Human STAT4
  • STAT4 was originally identified using degenerate primers complementary to sequences encoding conserved regions of other STAT proteins
  • The STAT4 protein is most similar to STAT1 (52%) and STAT3 (47%)
  • Functionally, STAT4 is similar to other STAT family members in that it can be tyrosine phosphorylated by Jak1 or Jak2
  • STAT4 forms homodimers and heterodimers with related STAT family members
  • Tyrosine phosphorylated STAT4 can bind the IFN-gamma activated site (GAS)
  • Serine phosphorylation of STAT is also required for maximal transcriptional activity
  • STAT4 expression is restricted to the thymus, spleen and testis
  • Until recently the cytokine(s) responsible for activation of STAT4 had not been identified
  • STAT4 is now known to be activated by the cytokine interleukin 12 (IL-12)
  • IL-12 is required for the T-cell independent induction of IFN-gamma which is a key step in the initial suppression of bacterial and parasitic infections
  • In addition, IL-12 is required for the development of a Th1 response which is necessary for effective host defense against intracellular pathogens
  • STAT4-deficient mice display impaired IL-12 development of Th1 cells and enhanced development of Th2 cells
  • A recent study in mouse has shown that in response to viral infection IFN-a/b activation of STAT4 is required for IFN-g production.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA581044

--


Antigen:
STAT4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAT4

Gene Alias:
CIS4; HSPC060; OTTHUMP00000163553; Signal transducer and activator of transcription 4; SLEB11; SOCS4; SOCS6; SSI4; STAI4; STAT; Stat4; STATI4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6775

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q14765

Gene Symbols:
STAT4

Immunogen:
A synthetic peptide corresponding to the C-terminus of the Human STAT4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA581045

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Antigen:
STAT5 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAT5A

Gene Alias:
AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6776

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
PBS with no preservative

Gene Accession No.:
P42229

Gene Symbols:
STAT5A

Immunogen:
A synthetic peptide corresponding to the C-terminus of the Human STAT5a

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA581047

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Antigen:
STIM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STIM1

Gene Alias:
D11S4896E; GOK; IMD10; RGD:1306831}; SIM; Stim1; stim1 {ECO:0000312; STIM1L; STRMK; Stromal interaction molecule 1; stromal interaction molecule 1 precursor; TAM; TAM1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6786

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
PBS with no preservative

Gene Accession No.:
Q13586

Gene Symbols:
STIM1

Immunogen:
Recombinant Human STIM1 protein (Met1-Asp213)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA581049

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Antigen:
OBFC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STN1

Gene Alias:
0610009H20Rik; 2310057J23Rik; AAF44; AAF-44; AI413458; alpha accessory factor 44; alpha-accessory factor of 44 kDa; bA541N10.2; CST complex subunit STN1; Obfc1; oligonucleotide/oligosaccharide binding fold containing 1; oligonucleotide/oligosaccharide-binding fold containing 1; oligonucleotide/oligosaccharide-binding fold-containing protein 1; replication protein A 32 kDa subunit; RPA-32; STN1; STN1 subunit of CST complex; STN1, CST complex subunit; suppressor of cdc thirteen homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
79991

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q9H668

Gene Symbols:
STN1

Immunogen:
A synthetic peptide corresponding to the center region of the Human OBFC1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG