PIPA581258
SIAH2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA581258-Each-of-1 | In Stock | ₹ 30,801.60 |
PIPA581258 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,801.60
GST (18%): ₹ 5,544.288
Total Price: ₹ 36,345.888
Antigen
SIAH2
Classification
Polyclonal
Formulation
PBS with no preservative
Gene Accession No.
O43255
Gene Symbols
SIAH2
Immunogen
A synthetic peptide corresponding to the C-terminus of the Human SIAH2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
SIAH2
Gene Alias
AA415433; E3 ubiquitin-protein ligase SIAH2; EC 6.3.2; hSiah2; mSiah2; RING-type E3 ubiquitin transferase SIAH2; seven in absentia 2; seven in absentia homolog 2; siah E3 ubiquitin protein ligase 2; SIAH2; siah-2; Sinh2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
6478
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- This antibody has specificity for Human SIAH2
- SIAH-2 (seven in absentia homolog 2) is an E3 ligase that catalyzes ubiquitination and proteasome-mediated degradation of protein substrates
- SIAH-2 encodes a 324 amino acid protein that shares 77% identity with human SIAH-1 and 68% identity with the Drosophila sina (seven in absentia) gene, on which development of the Drosophila R7 photoreceptor is dependent
- SIAH-2 targets TRAF2 (which regulates cell responses to stress and cytokines through the regulation of key stress-signaling cascades) for degradation under stress conditions such as hypoxia
- It targets HIF-1 alpha prolyl hydroxylase 3 (PHD3) for degradation upon exposure to hypoxic conditions, which coincides with an increase in SIAH-2 transcription
- SIAH-2 can decrease TNF-alpha-dependent induction of JNK activity and transcriptional activation of NFkB
- SIAH-2 null mice subjected to hypoxia display an impaired respiratory response and reduced levels of hemoglobin.
Compare Similar Items
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Antigen: SIAH2
Classification: Polyclonal
Formulation: PBS with no preservative
Gene Accession No.: O43255
Gene Symbols: SIAH2
Immunogen: A synthetic peptide corresponding to the C-terminus of the Human SIAH2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: SIAH2
Gene Alias: AA415433; E3 ubiquitin-protein ligase SIAH2; EC 6.3.2; hSiah2; mSiah2; RING-type E3 ubiquitin transferase SIAH2; seven in absentia 2; seven in absentia homolog 2; siah E3 ubiquitin protein ligase 2; SIAH2; siah-2; Sinh2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6478
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SIAH2
Classification:
Polyclonal
Formulation:
PBS with no preservative
Gene Accession No.:
O43255
Gene Symbols:
SIAH2
Immunogen:
A synthetic peptide corresponding to the C-terminus of the Human SIAH2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
SIAH2
Gene Alias:
AA415433; E3 ubiquitin-protein ligase SIAH2; EC 6.3.2; hSiah2; mSiah2; RING-type E3 ubiquitin transferase SIAH2; seven in absentia 2; seven in absentia homolog 2; siah E3 ubiquitin protein ligase 2; SIAH2; siah-2; Sinh2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6478
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: SIRT4
Classification: Polyclonal
Formulation: PBS with no preservative
Gene Accession No.: Q9Y6E7
Gene Symbols: SIRT4
Immunogen: A synthetic peptide corresponding to the C-terminus of the Human SIRT4
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: SIRT4
Gene Alias: 4930596O17Rik; MGC130046; MGC130047; MGC57437; NAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; NAD-dependent deacetylase sirtuin-4; NAD-dependent protein deacetylase sirtuin-4; NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; regulatory protein SIR2 homolog 4; SIR2L4; sir2-like 4; SIR2-like protein 4; SIRT4; sirtuin 4; sirtuin type 4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23409
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SIRT4
Classification:
Polyclonal
Formulation:
PBS with no preservative
Gene Accession No.:
Q9Y6E7
Gene Symbols:
SIRT4
Immunogen:
A synthetic peptide corresponding to the C-terminus of the Human SIRT4
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
SIRT4
Gene Alias:
4930596O17Rik; MGC130046; MGC130047; MGC57437; NAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; NAD-dependent deacetylase sirtuin-4; NAD-dependent protein deacetylase sirtuin-4; NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; regulatory protein SIR2 homolog 4; SIR2L4; sir2-like 4; SIR2-like protein 4; SIRT4; sirtuin 4; sirtuin type 4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23409
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: SMURF2
Classification: Polyclonal
Formulation: PBS with no preservative
Gene Accession No.: Q9HAU4
Gene Symbols: Smurf2
Immunogen: A synthetic peptide corresponding to the N-terminus of the Human SMURF2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Gene: Smurf2
Gene Alias: 2810411E22Rik; AI558114; AI649275; E3 ubiquitin ligase SMURF2; E3 ubiquitin-protein ligase SMURF2; HECT-type E3 ubiquitin transferase SMURF2; hSMURF2; RGD1310067; SMAD specific E3 ubiquitin protein ligase 2; SMAD ubiquitination regulatory factor 2; SMAD-specific E3 ubiquitin-protein ligase 2; SMURF2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 64750
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SMURF2
Classification:
Polyclonal
Formulation:
PBS with no preservative
Gene Accession No.:
Q9HAU4
Gene Symbols:
Smurf2
Immunogen:
A synthetic peptide corresponding to the N-terminus of the Human SMURF2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Gene:
Smurf2
Gene Alias:
2810411E22Rik; AI558114; AI649275; E3 ubiquitin ligase SMURF2; E3 ubiquitin-protein ligase SMURF2; HECT-type E3 ubiquitin transferase SMURF2; hSMURF2; RGD1310067; SMAD specific E3 ubiquitin protein ligase 2; SMAD ubiquitination regulatory factor 2; SMAD-specific E3 ubiquitin-protein ligase 2; SMURF2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
64750
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: STAT1
Classification: Polyclonal
Formulation: PBS with no preservative
Gene Accession No.: P42224
Gene Symbols: STAT1
Immunogen: A synthetic peptide corresponding to the C-terminus of the Human STAT1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: STAT1
Gene Alias: 2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6772
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
STAT1
Classification:
Polyclonal
Formulation:
PBS with no preservative
Gene Accession No.:
P42224
Gene Symbols:
STAT1
Immunogen:
A synthetic peptide corresponding to the C-terminus of the Human STAT1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
STAT1
Gene Alias:
2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6772
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid