PIPA581384

CD178 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA581384-Each-of-1 In Stock ₹ 30,801.60

PIPA581384 - Each of 1

₹ 30,801.60

In Stock

Quantity

1

Base Price: ₹ 30,801.60

GST (18%): ₹ 5,544.288

Total Price: ₹ 36,345.888

Antigen

CD178

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Fasl

Gene Alias

ADAM10-processed FasL form; ALPS1B; APL; Apoptosis (APO 1) antigen ligand 1; apoptosis (APO-1) antigen ligand 1; Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand); apoptosis antigen ligand; APT1LG1; APTL; CD178; CD178 antigen; CD95 ligand; CD95 ligand protein;Generalized lymphoproliferative disease (Gld); Cd95l; CD95-L; CD95L protein; fas antigen ligand; Fas ligand; Fas ligand (TNF superfamily, member 6); Fasl; Fas-L; FasL ICD; FasL intracellular domain; Faslg; Fas-LG; generalized lymphoproliferative disease; gld; mutant tumor necrosis factor family member 6; Receptor-binding FasL ectodomain; sFasL; Soluble Fas ligand; soluble form; SPA; SPPL2A-processed FasL form; TNFL; Tnfsf6; TNLG1A; Tumor necrosis factor (ligand) superfamily member 6; Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor ligand; tumor necrosis factor ligand 1A; tumor necrosis factor ligand superfamily member 6; Tumor necrosis factor ligand superfamily member 6 (TNFL6 / TNFSF6); Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

14103

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P41047

Gene Symbols

Fasl

Immunogen

A synthetic peptide corresponding to the C-terminus of the Mouse Fas Ligand/FASLG/CD95L

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA581084

--

Img

Thermo Scientific

PIPA581086

--

Img

Thermo Scientific

PIPA581483

--

Img

Thermo Scientific

PIPA579235

--

Img

Thermo Scientific

PIPA581619

--

Img

Thermo Scientific

PIPA581080

--

Img

Thermo Scientific

PIPA581566

--

Img

Thermo Scientific

PIPA581481

--

Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Mouse Fas Ligand/FASLG/CD95L
  • CD178 (Fas ligand, FasL) is a type-II-membrane protein, whose N-terminus is in the cytoplasm and its C-terminal region extends into the extracellular space
  • Its receptor, FasR, is a cell-surface-type-I-membrane protein and a member of the tumor necrosis factor (TNF) and nerve growth factor (NGF) receptor family
  • As a member of the TNF-cytokine family CD178 induces apoptosis when interacting with FasR
  • CD178 may exist as either membrane bound (45 kD) or soluble forms (26 kD)
  • The soluble protein can be released from cells upon cleavage by metalloproteinases
  • Binding of CD178 to Fas leads to oligomerization of the receptor and triggers apoptotic cell death through the interaction of other proteins
  • CD178 is predominantly expressed in activated T-lymphocytes and natural killer (NK) cells also it is expressed in the tissues of immune-privilege sites such as testis and eye
  • CD178 expression is also reported in various tissues as thymus, liver, ovary, lung, heart and kidney
  • It is assumed that induction of apoptosis through CD178 is predominantly involved in anti-viral immune responses
  • CD178 is a cell surface molecule belonging to the tumor necrosis factor family, binds to its receptor Fas, thus inducing apoptosis
  • Various cells express FAS, where CD178 is expressed predominantly on activated T cells
  • FAS and CD178 are involved in the down-regulation of immune reactions as well as T cell-mediated cytotoxicity
  • CD178 concentration has also been shown to be associated with atherosclerosis and inflammatory disease, in patients with hypertension
  • The Fas/ CD178 system has been shown to play a role in a number of human diseases, for example AIDS, hepatitis or cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA581384

--


Antigen:
CD178

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fasl

Gene Alias:
ADAM10-processed FasL form; ALPS1B; APL; Apoptosis (APO 1) antigen ligand 1; apoptosis (APO-1) antigen ligand 1; Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand); apoptosis antigen ligand; APT1LG1; APTL; CD178; CD178 antigen; CD95 ligand; CD95 ligand protein;Generalized lymphoproliferative disease (Gld); Cd95l; CD95-L; CD95L protein; fas antigen ligand; Fas ligand; Fas ligand (TNF superfamily, member 6); Fasl; Fas-L; FasL ICD; FasL intracellular domain; Faslg; Fas-LG; generalized lymphoproliferative disease; gld; mutant tumor necrosis factor family member 6; Receptor-binding FasL ectodomain; sFasL; Soluble Fas ligand; soluble form; SPA; SPPL2A-processed FasL form; TNFL; Tnfsf6; TNLG1A; Tumor necrosis factor (ligand) superfamily member 6; Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor ligand; tumor necrosis factor ligand 1A; tumor necrosis factor ligand superfamily member 6; Tumor necrosis factor ligand superfamily member 6 (TNFL6 / TNFSF6); Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14103

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P41047

Gene Symbols:
Fasl

Immunogen:
A synthetic peptide corresponding to the C-terminus of the Mouse Fas Ligand/FASLG/CD95L

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA581386

--


Antigen:
CD64

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fcgr1

Gene Alias:
AI323638; AV092959; CD64; CD64 antigen; CD64A; Fc fragment of IgG high affinity Ib receptor; Fc fragment of IgG receptor Ia; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc fragment of IgG, high affinity Ia, receptor for (CD64); Fc fragment of IgG, high affinity Ib, receptor for (CD64); Fc gamma receptor; Fc gamma receptor Ia; Fc receptor, IgG, high affinity I; Fcg1; Fc-gamma receptor 1; Fc-gamma receptor I A1; Fc-gamma RI; Fc-gamma RIA; FcgammaRI; FcgammaRIa; Fcgr1; FCGR1A; Fcgr1b; FcgRI; FCRI; FLJ18345; high affinity IgG Fc receptor, subunit beta; high affinity immunoglobulin gamma Fc receptor I; high-affinity immunoglobulin gamma Fc receptor I; IGFR1; IgG Fc receptor I; IgG high affinity Fc receptor; IGGHAFC; RP11-196G18.2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14129

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
__

Formulation:
PBS with no preservative

Gene Accession No.:
P26151

Gene Symbols:
Fcgr1

Immunogen:
Recombinant Mouse FCGR1 protein (Met1-Pro297)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA581387

--


Antigen:
FCRL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fcrl1

Gene Alias:
A230020G22Rik; Bxmas1; BXMAS1-like protein 1; BXMAS1-like protein 1b; Bxmh1; Bxmh1b; CD307a; CD307a antigen; fc receptor 1-like protein; fc receptor homolog 1; Fc receptor like 1; Fc receptor-like 1; Fc receptor-like protein 1; Fcrh1; FCRH1DKFZp667O1421; Fcrh1l; Fcrh1s; Fcrl1; FcR-like protein 1; hIFGP1; IFGP family protein 1; IFGP1; immune receptor translocation-associated protein 5; immunoglobulin superfamily Fc receptor, gp42; IRTA5; mBXMH1; mIFGP1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
229499

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
PBS with no preservative

Gene Accession No.:
Q8R4Y0

Gene Symbols:
Fcrl1

Immunogen:
Recombinant Mouse FCRL1/FCRH1 protein (Met1-Thr204)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA581388

--


Antigen:
FDPS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FDPS

Gene Alias:
(2E,6E)-farnesyl diphosphate synthase; 6030492I17Rik; Ac2-125; AI256750; cholesterol-regulated 39 kDa protein; CR 39; dimethylallyltranstransferase; Farnesyl diphosphate synthase; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase); farnesyl diphosphate synthetase; farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthetase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase; Fdps; Fdpsl1; FPP synthase; FPP synthetase; FPPS; FPS; geranyltranstransferase; KIAA1293; mKIAA1293; POROK9; testis-specific farnesyl pyrophosphate synthetase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
110196

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q920E5

Gene Symbols:
FDPS

Immunogen:
Recombinant Mouse FDPS/Farnesyl Diphosphate Synthase protein (Met1-Lys353)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG