PIPA581443
MCL-1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA581443-Each-of-1 | In Stock | ₹ 30,801.60 |
PIPA581443 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,801.60
GST (18%): ₹ 5,544.288
Total Price: ₹ 36,345.888
Antigen
MCL-1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MCL1
Gene Alias
AW556805; BCL2 family apoptosis regulator; BCL2L3; bcl2-L-3; Bcl-2-like protein 3; bcl-2-related protein EAT/mcl1; EAT; Induced myeloid leukemia cell differentiation protein Mcl-1; induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Mcl1; Mcl-1; mcl1/EAT; MCL1-ES; MCL1L; MCL1S; MCL-1S; MGC104264; MGC1839; myeloid cell leukemia 1; myeloid cell leukemia ES; myeloid cell leukemia sequence 1; myeloid cell leukemia sequence 1 (BCL2-related); TM
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
17210
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P97287
Gene Symbols
MCL1
Immunogen
A synthetic peptide corresponding to the center region of the Mouse Mcl-1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- This antibody has specificity for Mouse Mcl-1
- MCL1 (Myeloid cell leukemia-1) belongs to the Bcl-2 family and is involved in programing, differentiation and concomitant maintenance of cell viability, but not of proliferation
- Isoform 1 of MCL1 inhibits apoptosis while isoform 2 promotes it
- The carboxy terminal of MCL1 and bcl-2 share significant sequence homology
- Expression of MCL1 is increased upon exposure of ML-1 cells to various types of DNA damaging agents (e.g
- ionizing radiation, μgtraviolet radiation, and alkylating drugs) along with increases in GADD45 and Bax and a decrease in bcl-2
- Enhanced expression of MCL1, prominently associated with mitochondria, complements the continued expression of bcl-2 in ML-1 cells undergoing differentiation
- Like bcl-2, MCL1 has the capacity to promote cell viability under conditions that otherwise cause apoptosis
- While the mechanism by which MCL1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak
- MCL1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types
- MCL1 is essential for embryogenesis and for the development and maintenance of B and T lymphocytes in animals
- MCL1 exists as at least two distinct isoforms designated MCL1L and MCL1S
- In marked contrast to the larger isoform of MCL1, overexpression of MCL1S promotes cell death.
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Antigen: MCL-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MCL1
Gene Alias: AW556805; BCL2 family apoptosis regulator; BCL2L3; bcl2-L-3; Bcl-2-like protein 3; bcl-2-related protein EAT/mcl1; EAT; Induced myeloid leukemia cell differentiation protein Mcl-1; induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Mcl1; Mcl-1; mcl1/EAT; MCL1-ES; MCL1L; MCL1S; MCL-1S; MGC104264; MGC1839; myeloid cell leukemia 1; myeloid cell leukemia ES; myeloid cell leukemia sequence 1; myeloid cell leukemia sequence 1 (BCL2-related); TM
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17210
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P97287
Gene Symbols: MCL1
Immunogen: A synthetic peptide corresponding to the center region of the Mouse Mcl-1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MCL-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MCL1
Gene Alias:
AW556805; BCL2 family apoptosis regulator; BCL2L3; bcl2-L-3; Bcl-2-like protein 3; bcl-2-related protein EAT/mcl1; EAT; Induced myeloid leukemia cell differentiation protein Mcl-1; induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Mcl1; Mcl-1; mcl1/EAT; MCL1-ES; MCL1L; MCL1S; MCL-1S; MGC104264; MGC1839; myeloid cell leukemia 1; myeloid cell leukemia ES; myeloid cell leukemia sequence 1; myeloid cell leukemia sequence 1 (BCL2-related); TM
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17210
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P97287
Gene Symbols:
MCL1
Immunogen:
A synthetic peptide corresponding to the center region of the Mouse Mcl-1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: MEP1A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MEP1A
Gene Alias: AI098089; AW107200; bA268F1.1 (meprin A alpha (PABA peptide hydrolase)); E-24.18; Endopeptidase-2; endopeptidase-24.18 subunit alpha; Mep1; Mep-1; MEP1A; Mep-1a; meprin 1 alpha; meprin A alpha; meprin A alpha-subunit; meprin A subunit alpha; meprin A, alpha (PABA peptide hydrolase); meprin alpha; N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha; PABA peptide hydrolase; PPH alpha; PPHA
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17287
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Western Blot
Concentration: 5 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P28825
Gene Symbols: MEP1A
Immunogen: Recombinant Mouse MEP1A protein (Met1-Arg615)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MEP1A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MEP1A
Gene Alias:
AI098089; AW107200; bA268F1.1 (meprin A alpha (PABA peptide hydrolase)); E-24.18; Endopeptidase-2; endopeptidase-24.18 subunit alpha; Mep1; Mep-1; MEP1A; Mep-1a; meprin 1 alpha; meprin A alpha; meprin A alpha-subunit; meprin A subunit alpha; meprin A, alpha (PABA peptide hydrolase); meprin alpha; N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha; PABA peptide hydrolase; PPH alpha; PPHA
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17287
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Western Blot
Concentration:
5 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P28825
Gene Symbols:
MEP1A
Immunogen:
Recombinant Mouse MEP1A protein (Met1-Arg615)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: MIF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mif
Gene Alias: cytokine; delayed early response protein 6; DER6; GIF; GLIF; glutathione-binding 13 kDa protein; Glycosylation-inhibiting factor; HGNC:7097; L-dopachrome isomerase; L-dopachrome tautomerase; macrophage migration inhibitory factor; macrophage migration inhibitory factor (glycosylation-inhibiting factor); MGC107654; Mif; MMIF; phenylpyruvate tautomerase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17319
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P34884
Gene Symbols: Mif
Immunogen: Recombinant Mouse MIF protein (Pro2-Ala115)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MIF
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mif
Gene Alias:
cytokine; delayed early response protein 6; DER6; GIF; GLIF; glutathione-binding 13 kDa protein; Glycosylation-inhibiting factor; HGNC:7097; L-dopachrome isomerase; L-dopachrome tautomerase; macrophage migration inhibitory factor; macrophage migration inhibitory factor (glycosylation-inhibiting factor); MGC107654; Mif; MMIF; phenylpyruvate tautomerase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17319
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P34884
Gene Symbols:
Mif
Immunogen:
Recombinant Mouse MIF protein (Pro2-Ala115)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MSMB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MSMB
Gene Alias: beta-inhibin; beta-microseminoprotein; beta-MSP; HPC 13; HPC13; IGBF; immunoglobulin binding factor; Immunoglobulin-binding factor; microseminoprotein beta; microseminoprotein, beta; microseminoprotein, beta-; Msmb; MSP; MSPB; PIP; PN 44; PN44; Prostate secreted seminal plasma protein; prostate secretory protein of 94 amino acids; prostate secretory protein PSP94; prostatic inhibin protein; PRPS; PRSP; PSP; PSP 57; PSP57; PSP94; PSP-94; Seminal plasma beta-inhibin
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17695
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 0.03% ProClin 300; pH 7
Gene Accession No.: O08540
Gene Symbols: MSMB
Immunogen: A synthetic peptide corresponding to the center region of the Mouse IGBF/PRSP
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MSMB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MSMB
Gene Alias:
beta-inhibin; beta-microseminoprotein; beta-MSP; HPC 13; HPC13; IGBF; immunoglobulin binding factor; Immunoglobulin-binding factor; microseminoprotein beta; microseminoprotein, beta; microseminoprotein, beta-; Msmb; MSP; MSPB; PIP; PN 44; PN44; Prostate secreted seminal plasma protein; prostate secretory protein of 94 amino acids; prostate secretory protein PSP94; prostatic inhibin protein; PRPS; PRSP; PSP; PSP 57; PSP57; PSP94; PSP-94; Seminal plasma beta-inhibin
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17695
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 0.03% ProClin 300; pH 7
Gene Accession No.:
O08540
Gene Symbols:
MSMB
Immunogen:
A synthetic peptide corresponding to the center region of the Mouse IGBF/PRSP
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG