PIPA581540
ROCK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA581540-Each-of-1 | In Stock | ₹ 30,801.60 |
PIPA581540 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,801.60
GST (18%): ₹ 5,544.288
Total Price: ₹ 36,345.888
Antigen
ROCK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Rock1
Gene Alias
1110055K06Rik; Ac2-154; Liver regeneration-related protein LRRG199; MGC131603; MGC43611; p150 RhoA-binding kinase ROK beta; p160 ROCK-1; p160ROCK; p160-ROCK; PRO0435; Renal carcinoma antigen NY-REN-35; Rho associated coiled-coil containing protein kinase 1; Rho kinase; Rho-associated coiled-coil containing protein kinase 1; Rho-associated coiled-coil forming kinase 1; Rho-associated kinase beta; rho-associated protein kinase 1; Rho-associated, coiled-coil containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; Rho-associated, coiled-coil-containing protein kinase I; ROCK1; ROCK-I
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
6093
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunoprecipitation
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q13464
Gene Symbols
Rock1
Immunogen
A synthetic peptide corresponding to the C-terminus of the Human Rock1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- This antibody has specificity for Human ROCK1
- ROCK1 is a serine/threonine kinase that regulates cell differentiation and migration
- The Rho/ROCK pathway is involved in the progression of various human cancers
- ROCK1 has been found to be a new Caspase-3 substrate
- ROCK, one of the effectors of the small GTPase Rho, has recently been shown to contribute significantly to myosin light chain (MLC) activation through two pathways: direct phosphorylation of MLC and phosphorylation of MLC phosphatase, leading to its inhibition
- The increase in cellular contractility that is necessary for apoptotic membrane blebbing implies sustained augmentation of MLC phosphorylation
- ROCK-1 consists of an amino-terminal kinase domain and an inhibitory cysteine/histidine-rich C-terminal domain that is located within a pleckstrin-homology region
- They are joined by a variable region that contains the Rho-binding domain
- During apoptosis, ROCK-I is cleaved by caspase-3 at a conserved DETD1113/G sequence and its carboxy-terminal inhibitory domain is removed, resulting in deregulated and constitutive kinase activity
- The caspase-3-mediated cleavage and activation of ROCK I induces phosphorylation of MLC and membrane blebbing, one of the first events in the execution phase of apoptosis.
Compare Similar Items
Show Difference
Antigen: ROCK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Rock1
Gene Alias: 1110055K06Rik; Ac2-154; Liver regeneration-related protein LRRG199; MGC131603; MGC43611; p150 RhoA-binding kinase ROK beta; p160 ROCK-1; p160ROCK; p160-ROCK; PRO0435; Renal carcinoma antigen NY-REN-35; Rho associated coiled-coil containing protein kinase 1; Rho kinase; Rho-associated coiled-coil containing protein kinase 1; Rho-associated coiled-coil forming kinase 1; Rho-associated kinase beta; rho-associated protein kinase 1; Rho-associated, coiled-coil containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; Rho-associated, coiled-coil-containing protein kinase I; ROCK1; ROCK-I
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6093
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunoprecipitation
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q13464
Gene Symbols: Rock1
Immunogen: A synthetic peptide corresponding to the C-terminus of the Human Rock1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ROCK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Rock1
Gene Alias:
1110055K06Rik; Ac2-154; Liver regeneration-related protein LRRG199; MGC131603; MGC43611; p150 RhoA-binding kinase ROK beta; p160 ROCK-1; p160ROCK; p160-ROCK; PRO0435; Renal carcinoma antigen NY-REN-35; Rho associated coiled-coil containing protein kinase 1; Rho kinase; Rho-associated coiled-coil containing protein kinase 1; Rho-associated coiled-coil forming kinase 1; Rho-associated kinase beta; rho-associated protein kinase 1; Rho-associated, coiled-coil containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; Rho-associated, coiled-coil-containing protein kinase I; ROCK1; ROCK-I
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6093
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunoprecipitation
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q13464
Gene Symbols:
Rock1
Immunogen:
A synthetic peptide corresponding to the C-terminus of the Human Rock1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: RPS3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RPS3
Gene Alias: 40S ribosomal protein S3; D7Ertd795e; FLJ26283; FLJ27450; IMR-90 ribosomal protein S3; MGC87870; OK/SW-cl.26; OTTHUMP00000229804; OTTHUMP00000229805; OTTHUMP00000229874; OTTHUMP00000229877; OTTHUMP00000229878; OTTHUMP00000229879; OTTHUMP00000229880; OTTHUMP00000229882; OTTHUMP00000229883; OTTHUMP00000229886; ribosomal protein S3; Rps3; Rs_3; S3; Small ribosomal subunit protein uS3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6188
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P23396
Gene Symbols: RPS3
Immunogen: A synthetic peptide corresponding to the C-terminus of the Human RPS3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RPS3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RPS3
Gene Alias:
40S ribosomal protein S3; D7Ertd795e; FLJ26283; FLJ27450; IMR-90 ribosomal protein S3; MGC87870; OK/SW-cl.26; OTTHUMP00000229804; OTTHUMP00000229805; OTTHUMP00000229874; OTTHUMP00000229877; OTTHUMP00000229878; OTTHUMP00000229879; OTTHUMP00000229880; OTTHUMP00000229882; OTTHUMP00000229883; OTTHUMP00000229886; ribosomal protein S3; Rps3; Rs_3; S3; Small ribosomal subunit protein uS3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6188
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P23396
Gene Symbols:
RPS3
Immunogen:
A synthetic peptide corresponding to the C-terminus of the Human RPS3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SENP8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Senp8
Gene Alias: 9130010J17Rik; AU020827; DEN1; deneddylase 1; deneddylase-1; FKSG8; NEDD8 specific-protease cysteine 2; NEDD8-specific protease 1; Nedp1; protease, cysteine 2; protease, cysteine, 2 (NEDD8 specific); PRSC2; SENP8; sentrin/SUMO-specific protease SENP8; Sentrin-specific protease 8; SUMO sentrin specific protease family member 8; SUMO/sentrin peptidase family member, NEDD8 specific; SUMO/sentrin specific peptidase 8; SUMO/sentrin specific peptidase family member 8; SUMO/sentrin specific protease 8; SUMO/sentrin specific protease family member 8; Sumo1/sentrin/SMT3 specific peptidase 8
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 123228
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q96LD8
Gene Symbols: Senp8
Immunogen: A synthetic peptide corresponding to the N-terminus of the Human SENP8
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SENP8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Senp8
Gene Alias:
9130010J17Rik; AU020827; DEN1; deneddylase 1; deneddylase-1; FKSG8; NEDD8 specific-protease cysteine 2; NEDD8-specific protease 1; Nedp1; protease, cysteine 2; protease, cysteine, 2 (NEDD8 specific); PRSC2; SENP8; sentrin/SUMO-specific protease SENP8; Sentrin-specific protease 8; SUMO sentrin specific protease family member 8; SUMO/sentrin peptidase family member, NEDD8 specific; SUMO/sentrin specific peptidase 8; SUMO/sentrin specific peptidase family member 8; SUMO/sentrin specific protease 8; SUMO/sentrin specific protease family member 8; Sumo1/sentrin/SMT3 specific peptidase 8
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
123228
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q96LD8
Gene Symbols:
Senp8
Immunogen:
A synthetic peptide corresponding to the N-terminus of the Human SENP8
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SFXN5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Sfxn5
Gene Alias: BBG-TCC; C230001H08Rik; SFXN5; sideroflexin 5; sideroflexin-5; Tricarboxylate carrier BBG-TCC
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 94282
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.98 mg/mL
Formulation: PBS with 0.03% ProClin 300; pH 7
Gene Accession No.: Q925N0
Gene Symbols: Sfxn5
Immunogen: A synthetic peptide corresponding to the center region of the Mouse SFXN5
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SFXN5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Sfxn5
Gene Alias:
BBG-TCC; C230001H08Rik; SFXN5; sideroflexin 5; sideroflexin-5; Tricarboxylate carrier BBG-TCC
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
94282
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.98 mg/mL
Formulation:
PBS with 0.03% ProClin 300; pH 7
Gene Accession No.:
Q925N0
Gene Symbols:
Sfxn5
Immunogen:
A synthetic peptide corresponding to the center region of the Mouse SFXN5
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG