PIPA581609

LAIR1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA581609-Each-of-1 In Stock ₹ 30,801.60

PIPA581609 - Each of 1

₹ 30,801.60

In Stock

Quantity

1

Base Price: ₹ 30,801.60

GST (18%): ₹ 5,544.288

Total Price: ₹ 36,345.888

Antigen

LAIR1

Classification

Polyclonal

Formulation

PBS with no preservative

Gene Accession No.

P0C1X9

Gene Symbols

LAIR1

Immunogen

A synthetic peptide corresponding to the N-terminus of the Rat LAIR1/LAIR-1/CD305

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

LAIR1

Gene Alias

5133400O11Rik; BB115266; CD305; D7Bwg0421e; immunoglobulin heavy chain variable region; Lair1; Lair-1; leukocyte associated immunoglobulin like receptor 1; leukocyte-associated Ig-like receptor 1; leukocyte-associated Ig-like receptor-1; leukocyte-associated immunoglobulin-like receptor 1; rLAIR1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

574531

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Rat LAIR1/LAIR-1/CD305
  • LAIR1 (CD305) functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells
  • Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11
  • It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation
  • May also play its inhibitory role independently of SH2-containing phosphatases
  • Modulates cytokine production in CD4+ T-cells, down-regulating IL2 and IFNG production while inducing secretion of transforming growth factor beta
  • Down-regulates also IgG and IgE production in B-cells as well as IL8, IL10 and TNF secretion
  • Inhibits proliferation and induces apoptosis in myeloid leukemia cell lines as well as prevents nuclear translocation of NF-kappa-B p65 subunit/RELA and phosphorylation of I-kappa-B alpha/CHUK in these cells
  • Inhibits the differentiation of peripheral blood precursors towards dendritic cells.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA581609

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Antigen:
LAIR1

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P0C1X9

Gene Symbols:
LAIR1

Immunogen:
A synthetic peptide corresponding to the N-terminus of the Rat LAIR1/LAIR-1/CD305

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
LAIR1

Gene Alias:
5133400O11Rik; BB115266; CD305; D7Bwg0421e; immunoglobulin heavy chain variable region; Lair1; Lair-1; leukocyte associated immunoglobulin like receptor 1; leukocyte-associated Ig-like receptor 1; leukocyte-associated Ig-like receptor-1; leukocyte-associated immunoglobulin-like receptor 1; rLAIR1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
574531

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA581610

--


Antigen:
Layilin

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
0

Gene Symbols:
LAYN

Immunogen:
Recombinant Rat Layilin/LAYN protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Gene:
LAYN

Gene Alias:
E030012M19Rik; FLJ30977; FLJ31092; Gm511; layilin; LAYN; LYAN; RGD1564444; UNQ208/PRO234

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
500996

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA581611

--


Antigen:
LIFR

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
O70535

Gene Symbols:
Lifr

Immunogen:
Recombinant Rat LIFR/CD118 protein (Met1-Ser829)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Gene:
Lifr

Gene Alias:
A230075M04Rik; AW061234; CD118; CD118 antigen; D-factor/LIF receptor; FLJ98106; FLJ99923; leukemia inhibitor factor receptor alpha-chain; leukemia inhibitory factor receptor; leukemia inhibitory factor receptor alpha; leukemia inhibitory factor receptor alpha chain; LIF; LIF R beta; LIF receptor; Lifr; LIF-R; SJS2; soluble differentiation-stimulating factor receptor; STWS; SWS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
81680

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA581612

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Antigen:
MDH1

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
O88989

Gene Symbols:
MDH1

Immunogen:
Recombinant Rat MDHA/MDH1 protein (Met4-Ala334)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
MDH1

Gene Alias:
B230377B03Rik; Cytosolic malate dehydrogenase; D17921; Diiodophenylpyruvate reductase; epididymis secretory protein Li 32; HEL-S-32; malate dehydrogenase (EC 1.1.1.37); malate dehydrogenase 1; malate dehydrogenase 1, NAD (soluble); malate dehydrogenase, cytoplasmic; malate dehydrogenase, cytoplasmic; malate dehydrogenase, peroxisomal; malate dehydrogenase, soluble; Malate dehydrogenase-like enzyme; Mdh; Mdh1; MDHA; Mdhl; MDH-s; MDL1; MGC:1375; Mor2; Mor-2; soluble malate dehydrogenase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
24551

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid