PIPA581944

SHP-1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA581944-Each-of-1 In Stock ₹ 49,496.46

PIPA581944 - Each of 1

₹ 49,496.46

In Stock

Quantity

1

Base Price: ₹ 49,496.46

GST (18%): ₹ 8,909.363

Total Price: ₹ 58,405.823

Antigen

SHP-1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PTPN6

Gene Alias

70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

116689, 5777

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.08 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P29350, P81718

Gene Symbols

PTPN6

Immunogen

Recombinant protein corresponding to Human PTPN6

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: HAGPIIVHCS AGIGRTGTII VIDMLMENIS TKGLDCDIDI QKTIQMVRAQ RSGMVQTEAQ YKFIYVAIAQ FIETTKKKLE VLQSQKGQES EYGNITYPPA MKNAHAKASR TSSKHKEDVY ENLHTKNKRE EKVKKQRSAD KEKSKGSLK SHP-1 (PTPN6) is a non-receptor protein tyrosine phosphatase that is expressed primarily in hematopoietic cells
  • The enzyme is composed of two SH2 domains, a tyrosine phosphatase catalytic domain, and a carboxy-terminal regulatory domain
  • SHP-1 removes phosphates from target proteins to downregulate several tyrosine kinase-regulated pathways
  • In hematopoietic cells, the amino-terminal SH2 domain of SHP-1 binds to tyrosine phosphorylated erythropoietin receptors (EpoR) to negatively regulate hematopoietic growth
  • Overexpression of SHP-1 in epithelial cells results in dephosphorylation of the Ros receptor tyrosine kinase and subsequent downregulation of Ros-dependent cell proliferation and transformation
  • Following ligand binding in myeloid cells, SHP-1 associates with the IL-3R beta chain and downregulates IL-3-induced tyrosine phosphorylation and cell proliferation.

Compare Similar Items

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Img

Thermo Scientific

PIPA581944

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Antigen:
SHP-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN6

Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116689, 5777

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.08 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P29350, P81718

Gene Symbols:
PTPN6

Immunogen:
Recombinant protein corresponding to Human PTPN6

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA581945

--


Antigen:
STX7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Stx7

Gene Alias:
AI315064; AI317144; AW107239; STX7; Syn7; syntaxin 7; Syntaxin7; syntaxin-7; syntaxin-7-like; syntaxin-7-like protein; Unknown (protein for MGC:128117)

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
53331, 60466, 8417

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O15400, O70257, O70439

Gene Symbols:
Stx7

Immunogen:
Recombinant protein corresponding to Human STX7

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA581947

--


Antigen:
GPR64

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADGRG2

Gene Alias:
ADGRG2; adhesion G protein-coupled receptor G2; adhesion G-protein coupled receptor G2; AW212196; B830041D06Rik; CTD-2245E12.1; EDDM6; epididymal protein 6; epididymis-specific protein 6; FLJ00282; G protein-coupled receptor 64; G protein-coupled receptor, epididymis-specific (seven transmembrane family); Gpr64; G-protein coupled receptor 64; He6; Human epididymis-specific protein 6; LNB-TM7 heptahelical receptor Me6; Me6; MGC104454; MGC138738; MGC138739; Mouse epididymis-specific protein 6; Rat epididymis-specific protein 6; Re6; re6 receptor; TM7LN2

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10149

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8IZP9

Gene Symbols:
ADGRG2

Immunogen:
Recombinant protein corresponding to Human ADGRG2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA581948

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Antigen:
ECE1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ECE1

Gene Alias:
AW322500; Ece; ECE 1; ECE1; ECE-1; ECE-1a; ECE-1b; ECE-1d; endothelin converting enzyme 1; endothelin-converting enzyme 1; endothelin-converting enzyme-1a; endothelin-converting enzyme-1b; endothelin-converting enzyme-1d

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1889

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P42892

Gene Symbols:
ECE1

Immunogen:
Recombinant protein corresponding to Human ECE1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG