PIPA582201

GCAP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA582201-Each-of-1 In Stock ₹ 47,015.22

PIPA582201 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

GCAP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Guca1a

Gene Alias

C6orf131; COD3; cone dystrophy 3; CORD14; GC-A; GCAP; GCAP 1; GCAP1; Guanylate cyclase activator 1A; guanylate cyclase activator 1a (retina); guanylate cyclase-activating protein, photoreceptor 1; guanylin 1, retina; guanylyl cyclase-activating protein; guanylyl cyclase-activating protein 1; GUCA; GUCA1; GUCA1A; mGCAP1

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2978

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.3 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P43080

Gene Symbols

Guca1a

Immunogen

Recombinant protein corresponding to Human GUCA1A

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA553757

--

Img

Thermo Scientific

PIPA553977

--

Img

Thermo Scientific

PIPA558493

--

Img

Thermo Scientific

PIPA568208

--

Img

Thermo Scientific

PIPA561196

--

Img

Thermo Scientific

PIPA584657

--

Img

Thermo Scientific

PIPA582277

--

Img

Thermo Scientific

PIPA582174

--

Description

  • Immunogen sequence: EYVAALSLVL KGKVEQKLRW YFKLYDVDGN GCIDRDELLT IIQAIRAINP CSDTTMTAEE FTDTVFSKID VNGDGELSLE EFIEGVQKDQ MLLDTLTRSL DLTRIVRRLQ NGEQDEEGAD EAAEAAG Guanylate cyclase-activating protein is a l Ca(2+)-binding protein that upregulates synthesis of cGMP in photoreceptors
  • The known mammalian GCAPs are more than 90% similar, consisting of 201 to 205 amino acids, and containing 3 identically conserved Ca(2+)-binding sites
  • The GUCA1A gene, also termed GCAP1, is transcribed into a single 1.7-kb mRNA species detectable only in the retina
  • In a 4-generation British family with typical clinical features of autosomal dominant cone dystrophy a tyr99-to-cys mutation) in the GUCA1A gene has been identified
  • Another family with a pro50-to-leu mutation in GUCA1A demonstrated phenotypic variability ranging from mild photophobia to rod-cone dystrophy
  • The mutant protein could activate guanylate cyclase 1 (GUCY2D) and displayed similar calcium sensitivity to wildtype protein
  • However, there was a marked increase in the susceptibility to protease degradation and a reduction in the thermal stability of the pro50-to-leu mutation, which may depress cellular concentration and thereby contribute to retinal cell mortality.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA582201

--


Antigen:
GCAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Guca1a

Gene Alias:
C6orf131; COD3; cone dystrophy 3; CORD14; GC-A; GCAP; GCAP 1; GCAP1; Guanylate cyclase activator 1A; guanylate cyclase activator 1a (retina); guanylate cyclase-activating protein, photoreceptor 1; guanylin 1, retina; guanylyl cyclase-activating protein; guanylyl cyclase-activating protein 1; GUCA; GUCA1; GUCA1A; mGCAP1

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2978

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P43080

Gene Symbols:
Guca1a

Immunogen:
Recombinant protein corresponding to Human GUCA1A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA582202

--


Antigen:
MSX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MSX2

Gene Alias:
BB122635; CRS2; FPP; homeo box, msh-like 2; homeobox protein Hox-8; Homeobox protein Hox-8-1; homeobox protein MSX-2; homeobox, msh-like 2; HOX8; Hox-8; Hox8.1; Hox-8.1; MSH; msh homeo box 2; msh homeo box homolog 2; msh homeobox 2; msh homeobox homolog 2; MSX2; Msx-2; muscle segmentation homologue (MSX2); PFM; PFM1; Unknown (protein for MGC:142681)

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4488

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P35548

Gene Symbols:
MSX2

Immunogen:
Recombinant protein corresponding to Human MSX2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA582204

--


Antigen:
DLX5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DLX5

Gene Alias:
AI385752; distal-less homeo box 5; distal-less homeobox 5; distal-less homeobox protein 5; DLX-3; DLX5; Homeobox protein DLX-3; homeobox protein DLX-5; RDLX; SHFM1D; split hand/foot malformation type 1 with sensorineural hearing loss; Unknown (protein for MGC:137934)

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1749

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.24 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P56178

Gene Symbols:
DLX5

Immunogen:
Recombinant protein corresponding to Human DLX5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA582205

--


Antigen:
15-PGDH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HPGD

Gene Alias:
15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-PGDH; AV026552; HPGD; hydroxyprostaglandin dehydrogenase 15 (NAD); hydroxyprostaglandin dehydrogenase 15-(NAD); NAD+-dependent 15-hydroxyprostaglandin dehydrogenase; NAD-dependent 15-hydroxyprostaglandin dehydrogenase; PGDH; PGDH1; PHOAR1; Prostaglandin dehydrogenase 1; SDR36C1; Short chain dehydrogenase/reductase family 36C member 1; short chain dehydrogenase/reductase family 36C, member 1

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3248

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P15428

Gene Symbols:
HPGD

Immunogen:
Recombinant protein corresponding to Human HPGD

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG