PIPA582303
ROCK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA582303-Each-of-1 | In Stock | ₹ 50,309.28 |
PIPA582303 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,309.28
GST (18%): ₹ 9,055.67
Total Price: ₹ 59,364.95
Antigen
ROCK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Rock1
Gene Alias
1110055K06Rik; Ac2-154; Liver regeneration-related protein LRRG199; MGC131603; MGC43611; p150 RhoA-binding kinase ROK beta; p160 ROCK-1; p160ROCK; p160-ROCK; PRO0435; Renal carcinoma antigen NY-REN-35; Rho associated coiled-coil containing protein kinase 1; Rho kinase; Rho-associated coiled-coil containing protein kinase 1; Rho-associated coiled-coil forming kinase 1; Rho-associated kinase beta; rho-associated protein kinase 1; Rho-associated, coiled-coil containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; Rho-associated, coiled-coil-containing protein kinase I; ROCK1; ROCK-I
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19877, 6093, 81762
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P70335, Q13464, Q63644
Gene Symbols
Rock1
Immunogen
Recombinant protein corresponding to Human ROCK1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: TQVKELKEEI EEKNRENLKK IQELQNEKET LATQLDLAET KAESEQLARG LLEEQYFELT QESKKAASRN RQEITDKDHT VSRLEEANSM LTKDIEILRR ENEELTEKMK KAEEEYKLEK EEEISNLKAA FEKNINTERT ROCK1 is a serine/threonine kinase that regulates cell differentiation and migration
- The Rho/ROCK pathway is involved in the progression of various human cancers
- ROCK1 has been found to be a new Caspase-3 substrate
- ROCK, one of the effectors of the small GTPase Rho, has recently been shown to contribute significantly to myosin light chain (MLC) activation through two pathways: direct phosphorylation of MLC and phosphorylation of MLC phosphatase, leading to its inhibition
- The increase in cellular contractility that is necessary for apoptotic membrane blebbing implies sustained augmentation of MLC phosphorylation
- ROCK-1 consists of an amino-terminal kinase domain and an inhibitory cysteine/histidine-rich C-terminal domain that is located within a pleckstrin-homology region
- They are joined by a variable region that contains the Rho-binding domain
- During apoptosis, ROCK-I is cleaved by caspase-3 at a conserved DETD1113/G sequence and its carboxy-terminal inhibitory domain is removed, resulting in deregulated and constitutive kinase activity
- The caspase-3-mediated cleavage and activation of ROCK I induces phosphorylation of MLC and membrane blebbing, one of the first events in the execution phase of apoptosis.
Compare Similar Items
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Antigen: ROCK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Rock1
Gene Alias: 1110055K06Rik; Ac2-154; Liver regeneration-related protein LRRG199; MGC131603; MGC43611; p150 RhoA-binding kinase ROK beta; p160 ROCK-1; p160ROCK; p160-ROCK; PRO0435; Renal carcinoma antigen NY-REN-35; Rho associated coiled-coil containing protein kinase 1; Rho kinase; Rho-associated coiled-coil containing protein kinase 1; Rho-associated coiled-coil forming kinase 1; Rho-associated kinase beta; rho-associated protein kinase 1; Rho-associated, coiled-coil containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; Rho-associated, coiled-coil-containing protein kinase I; ROCK1; ROCK-I
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19877, 6093, 81762
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P70335, Q13464, Q63644
Gene Symbols: Rock1
Immunogen: Recombinant protein corresponding to Human ROCK1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ROCK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Rock1
Gene Alias:
1110055K06Rik; Ac2-154; Liver regeneration-related protein LRRG199; MGC131603; MGC43611; p150 RhoA-binding kinase ROK beta; p160 ROCK-1; p160ROCK; p160-ROCK; PRO0435; Renal carcinoma antigen NY-REN-35; Rho associated coiled-coil containing protein kinase 1; Rho kinase; Rho-associated coiled-coil containing protein kinase 1; Rho-associated coiled-coil forming kinase 1; Rho-associated kinase beta; rho-associated protein kinase 1; Rho-associated, coiled-coil containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; Rho-associated, coiled-coil-containing protein kinase I; ROCK1; ROCK-I
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19877, 6093, 81762
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P70335, Q13464, Q63644
Gene Symbols:
Rock1
Immunogen:
Recombinant protein corresponding to Human ROCK1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ACAT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Acat1
Gene Alias: 6330585C21Rik; Acat; Acat1; acetoacetyl Coenzyme A thiolase; acetoacetyl-CoA thiolase; acetyl-Co A acetyltransferase 1 mitochondrial; acetyl-CoA acetyltransferase 1; acetyl-CoA acetyltransferase, mitochondrial; acetyl-Coenzyme A acetyltransferase 1; MAT; mitochondrial acetoacetyl-CoA thiolase; RATACAL; T2; testicular tissue protein Li 198; THIL
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 38
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P24752
Gene Symbols: Acat1
Immunogen: Recombinant protein corresponding to Human ACAT1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ACAT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Acat1
Gene Alias:
6330585C21Rik; Acat; Acat1; acetoacetyl Coenzyme A thiolase; acetoacetyl-CoA thiolase; acetyl-Co A acetyltransferase 1 mitochondrial; acetyl-CoA acetyltransferase 1; acetyl-CoA acetyltransferase, mitochondrial; acetyl-Coenzyme A acetyltransferase 1; MAT; mitochondrial acetoacetyl-CoA thiolase; RATACAL; T2; testicular tissue protein Li 198; THIL
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
38
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P24752
Gene Symbols:
Acat1
Immunogen:
Recombinant protein corresponding to Human ACAT1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FER
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FER
Gene Alias: AV082135; C330004K01Rik; c-FER; EC 2.7.10.2; Feline encephalitis virus-related kinase FER; FER; fer (fms/fps related) protein kinase; fer (fms/fps related) protein kinase, testis specific 2; fer (fps/fes related) tyrosine kinase; FER tyrosine kinase; Fert; Fert2; Flk; Flk_retired; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; p47; p94-Fer; phosphoprotein NCP94; PPP1R74; protein phosphatase 1, regulatory subunit 74; proto-oncogene c-Fer; proto-oncogene tyrosine-protein kinase Fer; TYK3; Tyrosine kinase 3; tyrosine protein kinase FLK; tyrosine-protein kinase Fer; Tyrosine-protein kinase FLK
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2241
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P16591
Gene Symbols: FER
Immunogen: Recombinant protein corresponding to Human FER
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FER
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FER
Gene Alias:
AV082135; C330004K01Rik; c-FER; EC 2.7.10.2; Feline encephalitis virus-related kinase FER; FER; fer (fms/fps related) protein kinase; fer (fms/fps related) protein kinase, testis specific 2; fer (fps/fes related) tyrosine kinase; FER tyrosine kinase; Fert; Fert2; Flk; Flk_retired; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; p47; p94-Fer; phosphoprotein NCP94; PPP1R74; protein phosphatase 1, regulatory subunit 74; proto-oncogene c-Fer; proto-oncogene tyrosine-protein kinase Fer; TYK3; Tyrosine kinase 3; tyrosine protein kinase FLK; tyrosine-protein kinase Fer; Tyrosine-protein kinase FLK
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2241
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P16591
Gene Symbols:
FER
Immunogen:
Recombinant protein corresponding to Human FER
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TBC1D10A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TBC1D10A
Gene Alias: AC004997.C22.2; AI447804; dJ130H16.1; dJ130H16.2; EBP50-PDX interactor of 64 kDa; EBP50-PDZ interactor of 64 kD; EPI64; EPI64 protein; mFLJ00288; Rab27A-GAP-alpha; TBC1 domain family member 10A; TBC1 domain family, member 10A; TBC1D10; Tbc1d10a
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 83874
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9BXI6
Gene Symbols: TBC1D10A
Immunogen: Recombinant protein corresponding to Human TBC1D10A
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TBC1D10A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TBC1D10A
Gene Alias:
AC004997.C22.2; AI447804; dJ130H16.1; dJ130H16.2; EBP50-PDX interactor of 64 kDa; EBP50-PDZ interactor of 64 kD; EPI64; EPI64 protein; mFLJ00288; Rab27A-GAP-alpha; TBC1 domain family member 10A; TBC1 domain family, member 10A; TBC1D10; Tbc1d10a
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
83874
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9BXI6
Gene Symbols:
TBC1D10A
Immunogen:
Recombinant protein corresponding to Human TBC1D10A
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG