PIPA582639
FOXK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA582639-Each-of-1 | In Stock | ₹ 51,336.00 |
PIPA582639 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,336.00
GST (18%): ₹ 9,240.48
Total Price: ₹ 60,576.48
Antigen
FOXK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
FOXK1
Gene Alias
A630048H08Rik; AI463295; ENSMUSG00000075577; FHX; Fork head; forkhead box K1; forkhead box protein K1; FOXK1; FOXK1L; Gm10868; Mnf; myocyte nuclear factor; RGD1309643; wu:fi75f05; zgc:66237
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
221937
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P85037
Gene Symbols
FOXK1
Immunogen
Recombinant protein corresponding to Human FOXK1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: GVPGHTVTIL QPATPVTLGQ HHLPVRAVTQ NGKHAVPTNS LAGNAYALTS PLQLLATQAS SSAPVVVTRV CEVGPKEPAA AVAATATTTP ATATTASASA SSTGEPEVKR SRVEEPSGAV TTPAG Transcriptional regulator involved in different processes such as glucose metabolism, aerobic glycolysis, muscle cell differentiation and autophagy
- Recognizes and binds the forkhead DNA sequence motif (5'-GTAAACA-3') and can both act as a transcription activator or repressor, depending on the context (PubMed:17670796)
- Together with FOXK2, acts as a key regulator of metabolic reprogramming towards aerobic glycolysis, a process in which glucose is converted to lactate in the presence of oxygen
- Acts by promoting expression of enzymes for glycolysis (such as hexokinase-2 (HK2), phosphofructokinase, pyruvate kinase (PKLR) and lactate dehydrogenase), while suppressing further oxidation of pyruvate in the mitochondria by up-regulating pyruvate dehydrogenase kinases PDK1 and PDK4
- Probably plays a role in gluconeogenesis during overnight fasting, when lactate from white adipose tissue and muscle is the main substrate
- Involved in mTORC1-mediated metabolic reprogramming: in response to mTORC1 signaling, translocates into the nucleus and regulates the expression of genes associated with glycolysis and downstream anabolic pathways, such as HIF1A, thereby regulating glucose metabolism
- Together with FOXK2, acts as a negative regulator of autophagy in skeletal muscle: in response to starvation, enters the nucleus, binds the promoters of autophagy genes and represses their expression, preventing proteolysis of skeletal muscle proteins
- Acts as a transcriptional regulator of the myogenic progenitor cell population in skeletal muscle
- Binds to the upstream enhancer region (CCAC box) of myoglobin (MB) gene, regulating the myogenic progenitor cell population
- Promotes muscle progenitor cell proliferation by repressing the transcriptional activity of FOXO4, thereby inhibiting myogenic differentiation
- Involved in remodeling processes of adult muscles that occur in response to physiological stimuli
- Required to correct temporal orchestration of molecular and cellular events necessary for muscle repair
- Represses myogenic differentiation by inhibiting MEFC activity
- Positively regulates Wnt/beta-catenin signaling by translocating DVL into the nucleus (PubMed:25805136)
- Reduces virus replication, probably by binding the interferon stimulated response element (ISRE) to promote antiviral gene expression (PubMed:25852164)
- [UniProt]
Compare Similar Items
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Antigen: FOXK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FOXK1
Gene Alias: A630048H08Rik; AI463295; ENSMUSG00000075577; FHX; Fork head; forkhead box K1; forkhead box protein K1; FOXK1; FOXK1L; Gm10868; Mnf; myocyte nuclear factor; RGD1309643; wu:fi75f05; zgc:66237
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 221937
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P85037
Gene Symbols: FOXK1
Immunogen: Recombinant protein corresponding to Human FOXK1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FOXK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FOXK1
Gene Alias:
A630048H08Rik; AI463295; ENSMUSG00000075577; FHX; Fork head; forkhead box K1; forkhead box protein K1; FOXK1; FOXK1L; Gm10868; Mnf; myocyte nuclear factor; RGD1309643; wu:fi75f05; zgc:66237
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
221937
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P85037
Gene Symbols:
FOXK1
Immunogen:
Recombinant protein corresponding to Human FOXK1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PDI
Classification: Polyclonal
Conjugate: Unconjugated
Gene: P4hb
Gene Alias: 1810041F13Rik; AI661267; CaO19.12595; cellular thyroid hormone binding protein; cellular thyroid hormone-binding protein; CLCRP1; collagen prolyl 4-hydroxylase beta; DSI; Endoplasmic reticulum resident protein 59; Eps1p; ER protein 59; ERBA2L; ERp59; GIT; glutathione-insulin transhydrogenase; I79_002399; LOW QUALITY PROTEIN: protein disulfide-isomerase A2; MFP1; P4HB; p4hb.L; P4Hbeta; p55; p58; Pancreas-specific protein disulfide isomerase; pancreatic protein disulfide isomerase; PDA2; PDI; PDI (E.C.5.3.4.1); PDI1; PDI1P; Pdia1; pdia2; pdia2.L; PDIP; Pdipl; PDIR; PHDB; PO4DB; PO4HB; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide; PROHB; prolyl 4-hydroxylase beta polypeptide; Prolyl 4-hydroxylase subunit beta; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase, beta polypeptide L homeolog; prolyl 4-hydroxylase, beta polypeptide; prolyl 4-hydroxylase, beta subunit; protein disulfide isomerase; protein disulfide isomerase (pancreas) like; Protein disulfide isomerase (Prolyl 4-hydroxylase, beta polypeptide); protein disulfide isomerase A2; protein disulfide isomerase associated 2; protein disulfide isomerase family A member 2; protein disulfide isomerase family A member 2 L homeolog; protein disulfide isomerase family A, member 1; protein disulfide isomerase family A, member 2; protein disulfide isomerase PDI1; protein disulfide isomerase, pancreatic; protein disulfide isomerase/oxidoreductase; protein disulfide isomerase-associated 1; protein disulfide isomerase-associated 2; protein disulfide-isomerase; Protein disulfide-isomerase A2; protocollagen hydroxylase; Rho GDP dissociation inhibitor gamma; testicular secretory protein Li 32; Thbp; Thioredoxin-related glycoprotein 1; thyroid hormone-binding protein p55; TRG1; XELAEV_18043753mg; XELAEV_18045582mg; XPDIp; YCL043C; YCL313; YCL43C
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18453, 25506, 5034
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.08 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P04785, P07237, P09103
Gene Symbols: P4hb
Immunogen: Recombinant protein corresponding to Human P4HB
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PDI
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
P4hb
Gene Alias:
1810041F13Rik; AI661267; CaO19.12595; cellular thyroid hormone binding protein; cellular thyroid hormone-binding protein; CLCRP1; collagen prolyl 4-hydroxylase beta; DSI; Endoplasmic reticulum resident protein 59; Eps1p; ER protein 59; ERBA2L; ERp59; GIT; glutathione-insulin transhydrogenase; I79_002399; LOW QUALITY PROTEIN: protein disulfide-isomerase A2; MFP1; P4HB; p4hb.L; P4Hbeta; p55; p58; Pancreas-specific protein disulfide isomerase; pancreatic protein disulfide isomerase; PDA2; PDI; PDI (E.C.5.3.4.1); PDI1; PDI1P; Pdia1; pdia2; pdia2.L; PDIP; Pdipl; PDIR; PHDB; PO4DB; PO4HB; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide; PROHB; prolyl 4-hydroxylase beta polypeptide; Prolyl 4-hydroxylase subunit beta; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase, beta polypeptide L homeolog; prolyl 4-hydroxylase, beta polypeptide; prolyl 4-hydroxylase, beta subunit; protein disulfide isomerase; protein disulfide isomerase (pancreas) like; Protein disulfide isomerase (Prolyl 4-hydroxylase, beta polypeptide); protein disulfide isomerase A2; protein disulfide isomerase associated 2; protein disulfide isomerase family A member 2; protein disulfide isomerase family A member 2 L homeolog; protein disulfide isomerase family A, member 1; protein disulfide isomerase family A, member 2; protein disulfide isomerase PDI1; protein disulfide isomerase, pancreatic; protein disulfide isomerase/oxidoreductase; protein disulfide isomerase-associated 1; protein disulfide isomerase-associated 2; protein disulfide-isomerase; Protein disulfide-isomerase A2; protocollagen hydroxylase; Rho GDP dissociation inhibitor gamma; testicular secretory protein Li 32; Thbp; Thioredoxin-related glycoprotein 1; thyroid hormone-binding protein p55; TRG1; XELAEV_18043753mg; XELAEV_18045582mg; XPDIp; YCL043C; YCL313; YCL43C
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18453, 25506, 5034
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.08 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P04785, P07237, P09103
Gene Symbols:
P4hb
Immunogen:
Recombinant protein corresponding to Human P4HB
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Apolipoprotein L1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APOL1
Gene Alias: APOL; APO-L; APOL- I; APOL1; APOL-I; Apolipoprotein L; apolipoprotein L 1; apolipoprotein L, 1; Apolipoprotein L1; Apolipoprotein L-I; FSGS4; OTTHUMP00000028705
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8542
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: O14791
Gene Symbols: APOL1
Immunogen: Recombinant protein corresponding to Human APOL1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Apolipoprotein L1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APOL1
Gene Alias:
APOL; APO-L; APOL- I; APOL1; APOL-I; Apolipoprotein L; apolipoprotein L 1; apolipoprotein L, 1; Apolipoprotein L1; Apolipoprotein L-I; FSGS4; OTTHUMP00000028705
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8542
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
O14791
Gene Symbols:
APOL1
Immunogen:
Recombinant protein corresponding to Human APOL1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NADE
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BEX3
Gene Alias: AL033356; Bex; Bex3; brain expressed X-linked 3; brain-expressed X-linked protein 3; Brain-expressed X-linked protein 3 homolog; DXS6984E; DXWsu67e; Gcap27; granule cell antiserum positive 27; HGR74; Nade; nerve growth factor receptor (TNFRSF16) associated protein 1; nerve growth factor receptor associated protein 1; nerve growth factor receptor-associated protein 1; Ngfrap1; ovarian granulosa cell 13.0 kDa protein HGR74; p75NTR-associated cell death executor; protein BEX3; rBex3; RP13-349O20.1
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27018
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q00994
Gene Symbols: BEX3
Immunogen: Recombinant protein corresponding to Human BEX3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NADE
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BEX3
Gene Alias:
AL033356; Bex; Bex3; brain expressed X-linked 3; brain-expressed X-linked protein 3; Brain-expressed X-linked protein 3 homolog; DXS6984E; DXWsu67e; Gcap27; granule cell antiserum positive 27; HGR74; Nade; nerve growth factor receptor (TNFRSF16) associated protein 1; nerve growth factor receptor associated protein 1; nerve growth factor receptor-associated protein 1; Ngfrap1; ovarian granulosa cell 13.0 kDa protein HGR74; p75NTR-associated cell death executor; protein BEX3; rBex3; RP13-349O20.1
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27018
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q00994
Gene Symbols:
BEX3
Immunogen:
Recombinant protein corresponding to Human BEX3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG