PIPA583443

CD27 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA583443-Each-of-1 In Stock ₹ 51,336.00

PIPA583443 - Each of 1

₹ 51,336.00

In Stock

Quantity

1

Base Price: ₹ 51,336.00

GST (18%): ₹ 9,240.48

Total Price: ₹ 60,576.48

Antigen

CD27

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CD27

Gene Alias

CD antigen 27; CD27; CD27 antigen; CD27 molecule; CD27L receptor; LPFS2; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

939

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.08 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P26842

Gene Symbols

CD27

Immunogen

Recombinant protein corresponding to Human CD27

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: HQRRKYRSNK GESPVEPAEP CRYSCPREEE GSTIPIQEDY R CD27 is a 50 kDa member of the tumor necrosis factor (TNF) receptor superfamily that includes CD40 and CD30
  • The TNF superfamily members are known for the regulation of cell proliferation and death
  • In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined to lymphocytes
  • High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors
  • CD70 expression requires additional co-stimulatory and/or pro-inflammatory signals
  • CD27 is expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells
  • Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid
  • Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies
  • RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70
  • CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor
  • Diseases associated with CD27 dysfunction include Lymphoproliferative Syndrome 2 and Autosomal Recessive Lymphoproliferative Syndrome.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA583443

--


Antigen:
CD27

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD27

Gene Alias:
CD antigen 27; CD27; CD27 antigen; CD27 molecule; CD27L receptor; LPFS2; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
939

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.08 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P26842

Gene Symbols:
CD27

Immunogen:
Recombinant protein corresponding to Human CD27

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA583444

--


Antigen:
SNX15

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Snx15

Gene Alias:
1500032B08Rik, clone iota unknown protein, E130013C21Rik, hCG_23393, HSAF001435, OTTHUMP00000035515, SNX15, sorting nexin 15, sorting nexin-15

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29907

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q9NRS6

Gene Symbols:
Snx15

Immunogen:
Recombinant protein corresponding to Human SNX15

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA583446

--


Antigen:
DDX23

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ddx23

Gene Alias:
100 kDa U5 snRNP-specific protein; 3110082M05Rik; 4921506D17Rik; DDX23; DEAD (Asp-Glu-Ala-Asp) box polypeptide 23; DEAD box protein 23; DEAD-box helicase 23; probable ATP-dependent RNA helicase DDX23; prp28; PRP28 homolog; PRP28 homolog, yeast; PRP28p homolog; PRPF28; SNRNP100; U5 snRNP 100 kD protein; U5-100K; U5-100KD

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9416

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9BUQ8

Gene Symbols:
Ddx23

Immunogen:
Recombinant protein corresponding to Human DDX23

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA583447

--


Antigen:
CD7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD7

Gene Alias:
Cd7; CD7 antigen; CD7 antigen (p41); Cd7 molecule; GP40; LEU-9; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
924

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P09564

Gene Symbols:
CD7

Immunogen:
Recombinant protein corresponding to Human CD7

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG