PIPA583453
HEF1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA583453-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA583453 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
HEF1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NEDD9
Gene Alias
Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4739
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q14511
Gene Symbols
NEDD9
Immunogen
Recombinant protein corresponding to Human NEDD9
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: PPMRQAGRPD LRPEGVYDIP PTCTKPAGKD LHVKYNCDIP GAAEPVARRH QSLSPNHPPP QLGQSVGSQN DAYDVPRGVQ FLEPPA HEF-1 is a multifunctional protein involved in integrin-based signaling that affects cell motility, growth, apoptosis and oncogenic transformation
- The Cas family of docking proteins have been the subject of intense research because of their role in cell motility, growth, apoptosis and oncogenic transformation
- These proteins are substrates of focal adhesion kinase (FAK) and the Src family of tyrosine kinases two active targets for drug development
- HEF1 protein production increases levels of mRNA transcripts that encode proteins associated with motility, cell transformation and invasiveness, including several metalloproteinases, MLCK, p160ROCK and ErbBi
- HEF1 overproduction also mediates apoptosis in epithelial-derived cell lines, including MCF7 and HeLa cells
- Recent clinical studies at another institution have found that overexpression of BCAR1 (p130Cas), a related protein, is associated with tamoxifen resistance
- This highlights the importance of studying the role of this family of proteins in cancer prognosis.
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Antigen: HEF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NEDD9
Gene Alias: Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4739
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q14511
Gene Symbols: NEDD9
Immunogen: Recombinant protein corresponding to Human NEDD9
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HEF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NEDD9
Gene Alias:
Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4739
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q14511
Gene Symbols:
NEDD9
Immunogen:
Recombinant protein corresponding to Human NEDD9
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: STIP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STIP1
Gene Alias: epididymis secretory sperm binding protein Li 94n, HEL-S-94n, HOP, hsc70/Hsp90-organizing protein, Hsp70/Hsp90 organizing protein, Hsp70/Hsp90-organizing protein, IEF SSP 3521, IEF-SSP-3521, mSTI1, NY-REN-11 antigen, P60, Renal carcinoma antigen NY-REN-11, STI1, STI1L, Stip1, stress induced phosphoprotein 1, stress-induced phosphoprotein 1, stress-induced-phosphoprotein 1, stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein), stress-inducible protein, transformation-sensitive protein IEF SSP 3521
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10963
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P31948
Gene Symbols: STIP1
Immunogen: Recombinant protein corresponding to Human STIP1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
STIP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STIP1
Gene Alias:
epididymis secretory sperm binding protein Li 94n, HEL-S-94n, HOP, hsc70/Hsp90-organizing protein, Hsp70/Hsp90 organizing protein, Hsp70/Hsp90-organizing protein, IEF SSP 3521, IEF-SSP-3521, mSTI1, NY-REN-11 antigen, P60, Renal carcinoma antigen NY-REN-11, STI1, STI1L, Stip1, stress induced phosphoprotein 1, stress-induced phosphoprotein 1, stress-induced-phosphoprotein 1, stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein), stress-inducible protein, transformation-sensitive protein IEF SSP 3521
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10963
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P31948
Gene Symbols:
STIP1
Immunogen:
Recombinant protein corresponding to Human STIP1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: DNM1L
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DNM1L
Gene Alias: 6330417M19Rik, AI450666, C-terminal region, Dlp1, dnm1l, Dnm1p/Vps1p-like protein, Dnml1, Dnmlp1, Drp1, DVLP, DYMPLE, dynamin 1 like, dynamin 1-like, dynamin family member proline-rich carboxyl-terminal domain less, Dynamin-1-like protein, Dynamin-1-like protein-like protein, Dynamin-like protein, dynamin-like protein 1, dynamin-like protein 4, Dynamin-like protein IV, dynamin-related protein 1, DYNIV 11, DYNIV-11, EC 3.6.5.5, EGK_03514, EMPF, FLJ41912, HDYNIV, N-terminal region, python, similar to dynamin 1-like, VPS1, zgc:66163
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10059
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: O00429
Gene Symbols: DNM1L
Immunogen: Recombinant protein corresponding to Human DNM1L
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DNM1L
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DNM1L
Gene Alias:
6330417M19Rik, AI450666, C-terminal region, Dlp1, dnm1l, Dnm1p/Vps1p-like protein, Dnml1, Dnmlp1, Drp1, DVLP, DYMPLE, dynamin 1 like, dynamin 1-like, dynamin family member proline-rich carboxyl-terminal domain less, Dynamin-1-like protein, Dynamin-1-like protein-like protein, Dynamin-like protein, dynamin-like protein 1, dynamin-like protein 4, Dynamin-like protein IV, dynamin-related protein 1, DYNIV 11, DYNIV-11, EC 3.6.5.5, EGK_03514, EMPF, FLJ41912, HDYNIV, N-terminal region, python, similar to dynamin 1-like, VPS1, zgc:66163
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10059
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
O00429
Gene Symbols:
DNM1L
Immunogen:
Recombinant protein corresponding to Human DNM1L
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: DNAJC3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DNAJC3
Gene Alias: AA408985, ACPHD, AU067833, DnaJ (Hsp40) homolog, subfamily C, member 3, DnaJ (Hsp40) homolog, subfamily C, member 3A, DnaJ (Hsp40) homolog, subfamily C, member 3B, DnaJ heat shock protein family (Hsp40) member C3, dnaJ homolog subfamily C member 3, DNAJC3, Dnajc3a, Dnajc3b, Endoplasmic reticulum DNA J domain-containing protein 6, ERdj6, ER-resident protein ERdj6, FLJ21288, HP58, Interferon-induced, double-stranded RNA-activated protein kinase inhibitor, mp58, p58, p58IPK, PRKRI, Protein kinase inhibitor of 58 kDa, protein kinase inhibitor p58, protein kinase, interferon inducible double stranded RNA dependent inhibitor, protein-kinase, interferon-inducible double stranded RNA dependent inhibitor
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5611
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q13217
Gene Symbols: DNAJC3
Immunogen: Recombinant protein corresponding to Human DNAJC3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DNAJC3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DNAJC3
Gene Alias:
AA408985, ACPHD, AU067833, DnaJ (Hsp40) homolog, subfamily C, member 3, DnaJ (Hsp40) homolog, subfamily C, member 3A, DnaJ (Hsp40) homolog, subfamily C, member 3B, DnaJ heat shock protein family (Hsp40) member C3, dnaJ homolog subfamily C member 3, DNAJC3, Dnajc3a, Dnajc3b, Endoplasmic reticulum DNA J domain-containing protein 6, ERdj6, ER-resident protein ERdj6, FLJ21288, HP58, Interferon-induced, double-stranded RNA-activated protein kinase inhibitor, mp58, p58, p58IPK, PRKRI, Protein kinase inhibitor of 58 kDa, protein kinase inhibitor p58, protein kinase, interferon inducible double stranded RNA dependent inhibitor, protein-kinase, interferon-inducible double stranded RNA dependent inhibitor
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5611
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q13217
Gene Symbols:
DNAJC3
Immunogen:
Recombinant protein corresponding to Human DNAJC3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG