PIPA583615

SETD2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA583615-Each-of-1 In Stock ₹ 47,271.90

PIPA583615 - Each of 1

₹ 47,271.90

In Stock

Quantity

1

Base Price: ₹ 47,271.90

GST (18%): ₹ 8,508.942

Total Price: ₹ 55,780.842

Antigen

SETD2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Setd2

Gene Alias

4921524K10Rik, BC031601, FLJ16420, FLJ22472, FLJ23184, FLJ45883, HBP231, HIF1, HIF-1, HIP-1, histone-lysine N-methyltransferase SETD2, hSET2, HSPC069, huntingtin interacting protein 1, huntingtin yeast partner B, Huntingtin-interacting protein 1, Huntingtin-interacting protein B, HYPB, Kiaa1732, Kif9, kinesin family member 9, KMT3A, LLS, lysine N-methyltransferase 3A, p231HBP, Protein-lysine N-methyltransferase SETD2, SET domain containing 2, SET domain containing 2, histone lysine methyltransferase, SET domain-containing protein 2, SET2, Setd2

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29072

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin)

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

Q9BYW2

Gene Symbols

Setd2

Immunogen

Recombinant protein corresponding to Human SETD2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: NLGMTSPLPY DSLGYNAPHH PFAGYPPGYP MQAYVDPSNP NAGKVLLPTP SMDPVCSPAP YDHAQPLVGH STEPLSAPPP VPVVPHVAAP VEVSSSQYVA Histone methyltransferase that specifically trimethylates 'Lys-36' of histone H3 (H3K36me3) using dimethylated 'Lys-36' (H3K36me2) as substrate
  • Represents the main enzyme generating H3K36me3, a specific tag for epigenetic transcriptional activation
  • Plays a role in chromatin structure modulation during elongation by coordinating recruitment of the FACT complex and by interacting with hyperphosphorylated POLR2A
  • Acts as a key regulator of DNA mismatch repair in G1 and early S phase by generating H3K36me3, a mark required to recruit MSH6 subunit of the MutS alpha complex: early recruitment of the MutS alpha complex to chromatin to be replicated allows a quick identification of mismatch DNA to initiate the mismatch repair reaction
  • H3K36me3 also plays an essential role in the maintenance of a heterochromatic state, by recruiting DNA methyltransferase DNMT3A
  • H3K36me3 is also enhanced in intron-containing genes, suggesting that SETD2 recruitment is enhanced by splicing and that splicing is coupled to recruitment of elongating RNA polymerase
  • Required during angiogenesis
  • Recruited to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA583615

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Antigen:
SETD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Setd2

Gene Alias:
4921524K10Rik, BC031601, FLJ16420, FLJ22472, FLJ23184, FLJ45883, HBP231, HIF1, HIF-1, HIP-1, histone-lysine N-methyltransferase SETD2, hSET2, HSPC069, huntingtin interacting protein 1, huntingtin yeast partner B, Huntingtin-interacting protein 1, Huntingtin-interacting protein B, HYPB, Kiaa1732, Kif9, kinesin family member 9, KMT3A, LLS, lysine N-methyltransferase 3A, p231HBP, Protein-lysine N-methyltransferase SETD2, SET domain containing 2, SET domain containing 2, histone lysine methyltransferase, SET domain-containing protein 2, SET2, Setd2

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29072

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin)

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q9BYW2

Gene Symbols:
Setd2

Immunogen:
Recombinant protein corresponding to Human SETD2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA583616

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Antigen:
CD35

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CR1

Gene Alias:
C3 binding protein; C3b/C4b receptor; C3-binding protein; C3BR; C4BR; CD35; CD35 antigen; complement component (3b/4b) receptor 1 (Knops blood group); Complement Component (3b/4b) receptor 1 including Knops blood group system; complement component 3b/4b receptor 1 (Knops blood group); complement receptor type 1; CR1; KN; Knops blood group antigen

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1378

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P17927

Gene Symbols:
CR1

Immunogen:
Recombinant protein corresponding to Human CR1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA583618

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Antigen:
MEIOB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MEIOB

Gene Alias:
4930528F23Rik, C16orf73, C6H16orf73, gs129, Meiob, meiosis specific with OB domains, meiosis specific with OB-fold, meiosis-specific with OB domain-containing protein, MLZ-675, Protein expressed in male leptotene and zygotene spermatocytes 675

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
254528

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q8N635

Gene Symbols:
MEIOB

Immunogen:
Recombinant protein corresponding to Human MEIOB

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA583619

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Antigen:
Septin-9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SEPTIN9

Gene Alias:
AF17q25; eighth septin; Eseptin; E-septin; KIAA0991; MLL septin-like fusion; MLL septin-like fusion protein; MLL septin-like fusion protein MSF-A; MSF; MSF1; NAPB; Ov/Br septin; ovarian/breast septin; PNUTL4; SEPT9; SeptD1; septin 9; septin D1; SEPTIN9; Septin-9; septin-like protein; Sint1; SL3-3 integration site 1 protein; SLP; Slpa

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10801

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9UHD8

Gene Symbols:
SEPTIN9

Immunogen:
Recombinant protein corresponding to Human SEPT9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG