PIPA583750

UBC13 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA583750-Each-of-1 In Stock ₹ 50,309.28

PIPA583750 - Each of 1

₹ 50,309.28

In Stock

Quantity

1

Base Price: ₹ 50,309.28

GST (18%): ₹ 9,055.67

Total Price: ₹ 59,364.95

Antigen

UBC13

Classification

Polyclonal

Conjugate

Unconjugated

Gene

UBE2N

Gene Alias

1500026J17Rik, AL022654, BB101821, bendless protein, bendless-like ubiquitin conjugating enzyme, bendless-like ubiquitin-conjugating enzyme, Blu, E2 ubiquitin-conjugating enzyme N, epididymis secretory protein Li 71, HEL-S-71, MGC131857, MGC8489, UBC13, UbcH13, UbcH-ben, UBCHBEN, UBC13, UBE2N, Ubiquitin carrier protein N, ubiquitin conjugating enzyme E2 N, ubiquitin conjugating enzyme E2N, ubiquitin-conjugating enzyme E2 N, ubiquitin-conjugating enzyme E2N, ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13), ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast), ubiquitin-protein ligase N, yeast UBC13 homolog

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7334

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

P61088

Gene Symbols

UBE2N

Immunogen

Recombinant protein corresponding to Human UBE2N

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA584081

--

Img

Thermo Scientific

PIPA583038

--

Img

Thermo Scientific

PIPA583234

--

Img

Thermo Scientific

PIPA583370

--

Img

Thermo Scientific

PIPA583556

--

Img

Thermo Scientific

PIPA583250

--

Img

Thermo Scientific

PIPA583751

--

Img

Thermo Scientific

PIPA582870

--

Description

  • Immunogen sequence: IIKETQRLLA EPVPGIKAEP DESNARYFHV VIA The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains
  • This type of polyubiquitination does not lead to protein degradation by the proteasome
  • Mediates transcriptional activation of target genes
  • Plays a role in the control of progress through the cell cycle and differentiation
  • Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage
  • Acts together with the E3 ligases, HLTF and SHPRH, in the 'Lys-63'-linked poly-ubiquitination of PCNA upon genotoxic stress, which is required for DNA repair
  • Appears to act together with E3 ligase RNF5 in the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD
  • Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2N heterodimer acts in concert with TRIM5 to generate 'Lys-63'-linked polyubiquitin chains which activate the MAP3K7/TAK1 complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes
  • Together with RNF135 and UB2V1, catalyzes the viral RNA-dependent 'Lys-63'-linked polyubiquitination of RIG-I/DDX58 to activate the downstream signaling pathway that leads to interferon beta production
  • UBE2V1-UBE2N together with TRAF3IP2 E3 ubiquitin ligase mediate 'Lys-63'-linked polyubiquitination of TRAF6, a component of IL17A-mediated signaling pathway
  • (Uniprot)

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA583750

--


Antigen:
UBC13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UBE2N

Gene Alias:
1500026J17Rik, AL022654, BB101821, bendless protein, bendless-like ubiquitin conjugating enzyme, bendless-like ubiquitin-conjugating enzyme, Blu, E2 ubiquitin-conjugating enzyme N, epididymis secretory protein Li 71, HEL-S-71, MGC131857, MGC8489, UBC13, UbcH13, UbcH-ben, UBCHBEN, UBC13, UBE2N, Ubiquitin carrier protein N, ubiquitin conjugating enzyme E2 N, ubiquitin conjugating enzyme E2N, ubiquitin-conjugating enzyme E2 N, ubiquitin-conjugating enzyme E2N, ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13), ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast), ubiquitin-protein ligase N, yeast UBC13 homolog

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7334

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P61088

Gene Symbols:
UBE2N

Immunogen:
Recombinant protein corresponding to Human UBE2N

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA583751

--


Antigen:
USP22

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
USP22

Gene Alias:
AI427806, Deubiquitinating enzyme 22, KIAA1063, Ubiquitin carboxyl-terminal hydrolase 22, ubiquitin specific peptidase 22, ubiquitin specific protease 22, ubiquitin thioesterase 22, ubiquitin thiolesterase 22, ubiquitin-specific processing protease 22, ubiquitin-specific-processing protease 22, Usp22, USP3L

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23326

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q9UPT9

Gene Symbols:
USP22

Immunogen:
Recombinant protein corresponding to Human USP22

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA583752

--


Antigen:
PRNT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRNT

Gene Alias:
M8; prion protein (testis specific); PRNT

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
149830

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q86SH4

Gene Symbols:
PRNT

Immunogen:
Recombinant protein corresponding to Human PRNT

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA583753

--


Antigen:
RSK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPS6KA2

Gene Alias:
90 kDa ribosomal protein S6 kinase 2; 90kDa; D17Wsu134e; HU-2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1C; MAPKAPK1C; MAPKAPK-1c; mitogen-activated protein kinase-activated protein kinase 1C; p90rsk; p90-RSK 2; p90RSK2; p90-RSK3; pp90rsk; pp90RSK3; Protein-tyrosine kinase Mpk-9; ribosomal protein S6 kinase A2; ribosomal protein S6 kinase alpha 2; ribosomal protein S6 kinase alpha-2; ribosomal protein S6 kinase polypeptide 2; ribosomal protein S6 kinase, 90kD, polypeptide 2; ribosomal protein S6 kinase, 90kDa, polypeptide 2; ribosomal protein S6 kinase, polypeptide 2; ribosomal S6 kinase 3; Rps6ka2; Rps6ka-rs1; RSK; Rsk3; RSK-3; S6K-alpha; S6K-alpha 2; S6K-alpha2; S6K-alpha-2

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6196

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q15349

Gene Symbols:
RPS6KA2

Immunogen:
Recombinant protein corresponding to Human RPS6KA2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG