PIPA583817

CD163 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA583817-Each-of-1 In Stock ₹ 50,565.96

PIPA583817 - Each of 1

₹ 50,565.96

In Stock

Quantity

1

Base Price: ₹ 50,565.96

GST (18%): ₹ 9,101.873

Total Price: ₹ 59,667.833

Antigen

CD163

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CD163

Gene Alias

CD163, CD163 antigen, CD163 molecule, CD163v2, CD163v3, Hemoglobin scavenger receptor, M130, macrophage-associated antigen, MM130, putative CD163 antigen, SCARI1, Scavenger receptor cysteine-rich type 1 protein M130, sCD163, Soluble CD163, Soluble sCD163

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9332

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration

0.4 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

Q86VB7

Gene Symbols

CD163

Immunogen

Recombinant protein corresponding to Human CD163

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: SRGENLVHQI QYREMNSCLN ADDLDLMNSS ENSHESADFS AAELISVSKF LPISGMEKEA ILSHTEKENG N CD163 (M130 antigen, Ber-Mac3, Ki-M8, SM4) is a 130 kDa membrane glycoprotein, a member of the scavenger receptor cysteine-rich superfamily, and a receptor for the hemoglobin-haptoglobin complex
  • CD163 protects tissues from free hemoglobin-mediated oxidative damage, and may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme
  • CD163 is expressed exclusively on the cell surface of human monocytes and macrophages that evolve predominantly in the late phase of inflammation
  • Specifically, CD163 is present on all circulating monocytes and most tissue macrophages except those found in the mantle zone and germinal centers of lymphoid follicles, interdigitating reticulum cells and Langerhan's cells
  • CD163 is present on all CD14 positive monocytes, most CD64 positive monocytes, and shows higher expression on CD16 positive monocytes
  • CD163 is upregulated on mononuclear phagocytes by IL-10, IL-6 and dexamethasone
  • Lipopolysaccharide (LPS) and phorbol myristate acetate (PMA) both induce shedding of CD163 from the cell surface into plasma or cell supernatant
  • CD163 binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner, and exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP1S phenotype
  • Further, CD163 also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.

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PIPA583817

--


Antigen:
CD163

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD163

Gene Alias:
CD163, CD163 antigen, CD163 molecule, CD163v2, CD163v3, Hemoglobin scavenger receptor, M130, macrophage-associated antigen, MM130, putative CD163 antigen, SCARI1, Scavenger receptor cysteine-rich type 1 protein M130, sCD163, Soluble CD163, Soluble sCD163

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9332

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
0.4 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q86VB7

Gene Symbols:
CD163

Immunogen:
Recombinant protein corresponding to Human CD163

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA583818

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Antigen:
HIP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
St13

Gene Alias:
1110007I03Rik, 3110002K08Rik, AAG2, aging-associated protein 2, AW555194, FAM10A1, FAM10A4, heat shock 70kD protein binding protein, hedgehog interacting protein, hedgehog-interacting protein, HHIP, HIP, HOP, Hsc70-interacting protein, Hsp70 interacting protein, Hsp70-interacting protein, HSPABP, HSPABP1, hypothetical protein, p48, PRO0786, Progesterone receptor-associated p48 protein, Protein FAM10A1, Protein ST13 homolog, putative tumor suppressor ST13, RCJMB04_6h13, Renal carcinoma antigen NY-REN-33, SNC6, ST13, ST13 Hsp70 interacting protein, ST13, Hsp70 interacting protein, ST13P5, suppression of tumorigenicity 13, suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein), suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 5, suppression of tumorigenicity 13 (colon carcinoma) Hsp70-interacting protein, suppression of tumorigenicity 13 protein, testis secretory sperm-binding protein Li 233m, UNQ5825/PRO19644

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6767

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P50502

Gene Symbols:
St13

Immunogen:
Recombinant protein corresponding to Human ST13

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA583819

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Antigen:
SPANXC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPANXC

Gene Alias:
C; cancer/testis antigen 11.3; cancer/testis antigen family 11, member 3; cancer/testis-associated protein CTp11; cancer/testis-associated protein of 11 kD; cancer-testis-associated protein CTp11; CT11.3; CTp11; nuclear-associated protein SPAN-Xc; SPANX family member C; SPANX family, member C; SPANXC; SPANX-C; SPAN-Xc protein; Sperm protein associated with the nucleus on the X chromosome C; sperm protein associated with the nucleus, X chromosome, family member C

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64663

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NY87

Gene Symbols:
SPANXC

Immunogen:
Recombinant protein corresponding to Human SPANXC

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA583820

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Antigen:
Cardiac Troponin I

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNNI3

Gene Alias:
alternatively spliced; cardiac ankyrin repeat kinase; Cardiac muscle troponin T; cardiac troponin I; cardiac troponin I isoform; cardiac troponin I-interacting kinase; cardiac troponin T; cardiac troponin T isoform 1; cardiac troponin T isoform 2; cardiac troponin T2; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, dilated 2A (autosomal recessive); cardiomyopathy, hypertrophic 2; CARK; CCDD; CMD1D; CMD1FF; CMD2A; CMH2; CMH7; CMPD2; cTnI; cTnT; Ctt; CTTG; D830019J24Rik; LVNC6; MGC116817; RATCTTG; RCM1; RCM3; Serine/threonine-protein kinase TNNI3K; Tn1; TnI; TNNC1; Tnni3; TNNI3 interacting kinase; TNNI3-interacting kinase; TNNI3K; tnni3k {ECO:0000250; TNNT2; Tnnt3; TnTc; Tpn1; troponin 1, type 3; troponin I type 3 (cardiac); troponin I, cardiac 3; troponin I, cardiac muscle; troponin I, cardiac muscle-like; troponin I3, cardiac type; Troponin T cardiac; troponin T cardiac isoform; troponin T isoform 1; troponin T isoform 2; troponin T splicing mutant isoform 1; troponin T splicing mutant isoform 2; troponin T type 2 (cardiac); troponin T, cardiac muscle; troponin T2, cardiac; troponin T2, cardiac type; truncated cardiac troponin T; UniProtKB:Q59H18}

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7137

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P19429

Gene Symbols:
TNNI3

Immunogen:
Recombinant protein corresponding to Human TNNI3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG