PIPA583930

MDMX Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA583930-Each-of-1 In Stock ₹ 47,015.22

PIPA583930 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

MDMX

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MDM4

Gene Alias

4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4194

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.6 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O15151

Gene Symbols

MDM4

Immunogen

Recombinant protein corresponding to Human MDM4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA583621

--

Img

Thermo Scientific

PIPA583170

--

Img

Thermo Scientific

PIPA583350

--

Img

Thermo Scientific

PIPA584188

--

Img

Thermo Scientific

PIPA582788

--

Img

Thermo Scientific

PIPA582998

--

Img

Thermo Scientific

PIPA583874

--

Img

Thermo Scientific

PIPA582978

--

Description

  • Immunogen sequence: LSDDTDVEVT SEDEWQCTEC KKFNSPSKRY CFRCWALRKD WYSDCSKLTH SLSTSDITAI PEKENEGNDV PDCRRTISAP VVRPKDAYIK KENS The MDM2 protein is the primary regulator of p53 protein stability
  • MDMX is an MDM2-related protein that inhibits MDM2-mediated degradation of p53 via distinct associations with MDM2
  • The gene that encodes MDMX (also designated MDM4) is a target for amplification in malignant gliomas
  • ARF interacts with MDMX to sequester MDMX within the nucleolus
  • This sequestration of MDMX by ARF results in an increase in p53 transactivation
  • In addition, expression of MDMX can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation
  • Like MDM2, MDMX also binds p73 and stabilizes the level of p73
  • Therefore, in striking contrast to p53, the half-life of p73 is increased by binding to MDM2.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA583930

--


Antigen:
MDMX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MDM4

Gene Alias:
4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4194

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.6 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O15151

Gene Symbols:
MDM4

Immunogen:
Recombinant protein corresponding to Human MDM4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA583931

--


Antigen:
Calmyrin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cib1

Gene Alias:
calcium and integrin binding 1; calcium and integrin binding 1 (calmyrin); calcium and integrin binding protein 1; calcium and integrin binding, protein kinase interacting protein; Calcium- and integrin-binding protein; calcium and integrin-binding protein 1; calmyrin; CIB; CIB1; Cibkip; CIBP; DNA-dependent protein kinase interacting protein; DNA-PK interaction protein; DNA-PKcs-interacting protein; Kinase-interacting protein; KIP; KIP1; LOW QUALITY PROTEIN: calcium and integrin-binding protein 1; PRKDCIP; protein kinase, DNA activated, catalytic polypeptide interacting protein; Sip2-28; SNK-interacting protein 2-28; testicular secretory protein Li 9

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10519

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q99828

Gene Symbols:
Cib1

Immunogen:
Recombinant protein corresponding to Human CIB1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA583932

--


Antigen:
EPHX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPHX1

Gene Alias:
AI195553, Eph1, Eph-1, EPHX, Ephx1, EPOX, Epoxide hydratase, epoxide hydrolase 1, epoxide hydrolase 1 (microsomal xenobiotic hydrolase), epoxide hydrolase 1 microsomal, epoxide hydrolase 1, microsomal, epoxide hydrolase 1, microsomal (xenobiotic), Epxh1, HYL1, liver microsomal xenobiotic epoxide hydrolase, mEH, MEH8, microsomal epoxide hydrolase, microsomal epoxide hydrolase (EC 3.3.2.3)

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2052

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P07099

Gene Symbols:
EPHX1

Immunogen:
Recombinant protein corresponding to Human EPHX1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA583933

--


Antigen:
CaV1.1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CACNA1S

Gene Alias:
AW493108, CACH1, Cacn1, Cacna1s, Cacnl1a3, calcium channel, L type, alpha 1 polypeptide, isoform 3 (skeletal muscle, hypokalemic periodic paralysis), calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle, calcium channel, voltage-dependent, L type, alpha 1S subunit, calcium voltage-gated channel subunit alpha1 S, Cav1.1, Cav1.1 alpha-1, CCHL1A3, DHP, DHPR, DHPR alpha1s, dihydropyridine calcium channel receptor protein, dihydropyridine receptor, dihydropyridine receptor alpha 1 subunit, dihydropyridine receptor alpha 1S, dihydropyridine receptor alpha-1S subunit, dihydropyridine-sensitive L-type calcium channel alpha-1 subunit, fmd, HOKPP, HOKPP1, hypoPP, mdg, MHS5, muscle dysgenesis, ROB1, sj, TTPP1, unnamed protein product, voltage-dependent L-type calcium channel subunit alpha-1S, Voltage-gated calcium channel subunit alpha Cav1.1

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
779

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q13698

Gene Symbols:
CACNA1S

Immunogen:
Recombinant protein corresponding to Human CACNA1S

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG