PIPA584187
B7-H4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA584187-Each-of-1 | In Stock | ₹ 47,528.58 |
PIPA584187 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,528.58
GST (18%): ₹ 8,555.144
Total Price: ₹ 56,083.724
Antigen
B7-H4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Vtcn1
Gene Alias
B7 family member, H4, B7 homolog 4, B7 superfamily member 1, B7h.5, B7H4, B7-H4, B7s1, B7x, BC032925, EMBL:AAH95842.1}, FLJ22418, immune costimulatory protein B7-H4, PRO1291, Protein B7S1, RGD1311204, RP11-229A19.4, t cell costimulatory molecule B7x, T-cell costimulatory molecule B7x, UNQ659/PRO1291, VCTN1, V-set domain containing T cell activation inhibitor 1, V-set domain containing T-cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1, Vtcn1, vtcn1 {ECO:0000312
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
79679
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
Q7Z7D3
Gene Symbols
Vtcn1
Immunogen
Recombinant protein corresponding to Human VTCN1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: ISGRHSITVT TVASAGNIGE DGILSCTFEP DIKLSDIVIQ WLKEGVLGLV HEFKEGKDEL SEQDEMFRGR TAVFADQVIV GNASLRL B7-H4 (B7x, VTCN1) a costimulatory protein which is reported to function as a negative regulator of T-cell mediated immunity
- Although B7-H4 binds an unknown receptor, it is thought to deliver an inhibitory signal to T-cells preventing their proliferation, cell cycle progression and interleukin-2 production
- B7-H4 deficient mice are only minimally affected; suggesting B7-H4 is important in the fine tuning of the T-cell mediated immune response
- B7-H4 is expressed on activated T-cells, B-cells, monocytes and dendritic cells
- Aberrant expression has been associated with cancers of the lung, breast and ovary in humans
- B7-H4 is expressed primarily on the membrane of lymphoid cells, and as an immunoinhibitory protein that interacts with receptors on the surface of T lymphocytes, it is involved in mediating cellular and humoral immune responses
- Overexpression of B7-H4 is associated with certain malignancies, including ovarian and breast cancer, which may be a mechanism by which tumor cells suppress T cell immunity and facilitate tumor progression
- Further, VTCN1 may be a useful biomarker for the early detection of ovarian cancer and Renal Cell Carcinoma (RCC).
Compare Similar Items
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Antigen: B7-H4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Vtcn1
Gene Alias: B7 family member, H4, B7 homolog 4, B7 superfamily member 1, B7h.5, B7H4, B7-H4, B7s1, B7x, BC032925, EMBL:AAH95842.1}, FLJ22418, immune costimulatory protein B7-H4, PRO1291, Protein B7S1, RGD1311204, RP11-229A19.4, t cell costimulatory molecule B7x, T-cell costimulatory molecule B7x, UNQ659/PRO1291, VCTN1, V-set domain containing T cell activation inhibitor 1, V-set domain containing T-cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1, Vtcn1, vtcn1 {ECO:0000312
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79679
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q7Z7D3
Gene Symbols: Vtcn1
Immunogen: Recombinant protein corresponding to Human VTCN1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
B7-H4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Vtcn1
Gene Alias:
B7 family member, H4, B7 homolog 4, B7 superfamily member 1, B7h.5, B7H4, B7-H4, B7s1, B7x, BC032925, EMBL:AAH95842.1}, FLJ22418, immune costimulatory protein B7-H4, PRO1291, Protein B7S1, RGD1311204, RP11-229A19.4, t cell costimulatory molecule B7x, T-cell costimulatory molecule B7x, UNQ659/PRO1291, VCTN1, V-set domain containing T cell activation inhibitor 1, V-set domain containing T-cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1, Vtcn1, vtcn1 {ECO:0000312
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79679
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q7Z7D3
Gene Symbols:
Vtcn1
Immunogen:
Recombinant protein corresponding to Human VTCN1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: RNF40
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RNF40
Gene Alias: 95 kDa retinoblastoma protein binding protein; 95 kDa retinoblastoma-associated protein; AI848422; BRE1 E3 ubiquitin ligase homolog B; Bre1b; BRE1-B; DKFZp686K191; E3 ubiquitin-protein ligase BRE1B; KIAA0661; MGC13051; mKIAA0661; protein staring; Rb-associated protein; RBP95; RING finger protein 40; ring finger protein 40, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1B; Rnf40; STARING; staring protein; syntaxin-1-interacting RING finger protein
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9810
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: O75150
Gene Symbols: RNF40
Immunogen: Recombinant protein corresponding to Human RNF40
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RNF40
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RNF40
Gene Alias:
95 kDa retinoblastoma protein binding protein; 95 kDa retinoblastoma-associated protein; AI848422; BRE1 E3 ubiquitin ligase homolog B; Bre1b; BRE1-B; DKFZp686K191; E3 ubiquitin-protein ligase BRE1B; KIAA0661; MGC13051; mKIAA0661; protein staring; Rb-associated protein; RBP95; RING finger protein 40; ring finger protein 40, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1B; Rnf40; STARING; staring protein; syntaxin-1-interacting RING finger protein
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9810
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
O75150
Gene Symbols:
RNF40
Immunogen:
Recombinant protein corresponding to Human RNF40
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: IDUA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IDUA
Gene Alias: 6030426D08, Alpha-L-iduronidase, IDA, IDUA, iduronidase alpha-L-, iduronidase, alpha-L-, MPS1
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3425
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P35475
Gene Symbols: IDUA
Immunogen: Recombinant protein corresponding to Human IDUA
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
IDUA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IDUA
Gene Alias:
6030426D08, Alpha-L-iduronidase, IDA, IDUA, iduronidase alpha-L-, iduronidase, alpha-L-, MPS1
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3425
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P35475
Gene Symbols:
IDUA
Immunogen:
Recombinant protein corresponding to Human IDUA
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TIPRL
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TIPRL
Gene Alias: 1810011K17Rik; CG9578-like; dJ69E11.3; MGC3794; OTTHUMP00000032581; OTTHUMP00000032582; putative MAPK-activating protein PM10; RGD1310442; TIP; TIP41; TIP41, TOR signaling pathway regulator-like; TIP41, TOR signalling pathway regulator-like (S. cerevisiae); TIP41-like protein; Tiprl; TIPRL1; TOR signaling pathway regulator; type 2A-interacting protein
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 261726
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: O75663
Gene Symbols: TIPRL
Immunogen: Recombinant protein corresponding to Human TIPRL
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TIPRL
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TIPRL
Gene Alias:
1810011K17Rik; CG9578-like; dJ69E11.3; MGC3794; OTTHUMP00000032581; OTTHUMP00000032582; putative MAPK-activating protein PM10; RGD1310442; TIP; TIP41; TIP41, TOR signaling pathway regulator-like; TIP41, TOR signalling pathway regulator-like (S. cerevisiae); TIP41-like protein; Tiprl; TIPRL1; TOR signaling pathway regulator; type 2A-interacting protein
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
261726
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
O75663
Gene Symbols:
TIPRL
Immunogen:
Recombinant protein corresponding to Human TIPRL
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG