CD178 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA584227-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA584227 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
CD178
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Faslg
Gene Alias
ADAM10-processed FasL form, ALPS1B, APL, Apoptosis (APO 1) antigen ligand 1, apoptosis (APO-1) antigen ligand 1, Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand), apoptosis antigen ligand, APT1LG1, APTL, CD178, CD178 antigen, CD95 ligand, CD95 ligand protein;Generalized lymphoproliferative disease (Gld), Cd95l, CD95-L, CD95L protein, fas antigen ligand, Fas ligand, Fas ligand (TNF superfamily, member 6), Fasl, Fas-L, FasL ICD, FasL intracellular domain, Faslg, Fas-LG, generalized lymphoproliferative disease, gld, mutant tumor necrosis factor family member 6, Receptor-binding FasL ectodomain, sFasL, Soluble Fas ligand, soluble form, SPA, SPPL2A-processed FasL form, TNFL, Tnfsf6, TNLG1A, Tumor necrosis factor (ligand) superfamily member 6, Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand), Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand), Tumor necrosis factor ligand, tumor necrosis factor ligand 1A, tumor necrosis factor ligand superfamily member 6, Tumor necrosis factor ligand superfamily member 6 (TNFL6 / TNFSF6), Tumor necrosis factor ligand superfamily member 6, membrane form, Tumor necrosis factor ligand superfamily member 6, soluble form
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
356
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P48023
Gene Symbols
Faslg
Immunogen
Recombinant protein corresponding to Human FASLG
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: HTASSLEKQI GHPSPPPEKK ELRKVAHLTG KSNSRSMPLE WEDTYGIVLL SGVKYKKGGL VINETGLYFV CD178 (Fas ligand, FasL) is a type-II-membrane protein, whose N-terminus is in the cytoplasm and its C-terminal region extends into the extracellular space
- Its receptor, FasR, is a cell-surface-type-I-membrane protein and a member of the tumor necrosis factor (TNF) and nerve growth factor (NGF) receptor family
- As a member of the TNF-cytokine family CD178 induces apoptosis when interacting with FasR
- CD178 may exist as either membrane bound (45 kD) or soluble forms (26 kD)
- The soluble protein can be released from cells upon cleavage by metalloproteinases
- Binding of CD178 to Fas leads to oligomerization of the receptor and triggers apoptotic cell death through the interaction of other proteins
- CD178 is predominantly expressed in activated T-lymphocytes and natural killer (NK) cells also it is expressed in the tissues of immune-privilege sites such as testis and eye
- CD178 expression is also reported in various tissues as thymus, liver, ovary, lung, heart and kidney
- It is assumed that induction of apoptosis through CD178 is predominantly involved in anti-viral immune responses
- CD178 is a cell surface molecule belonging to the tumor necrosis factor family, binds to its receptor Fas, thus inducing apoptosis
- Various cells express FAS, where CD178 is expressed predominantly on activated T cells
- FAS and CD178 are involved in the down-regulation of immune reactions as well as T cell-mediated cytotoxicity
- CD178 concentration has also been shown to be associated with atherosclerosis and inflammatory disease, in patients with hypertension
- The Fas/ CD178 system has been shown to play a role in a number of human diseases, for example AIDS, hepatitis or cancer.
Compare Similar Items
Show Difference
Antigen: CD178
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Faslg
Gene Alias: ADAM10-processed FasL form, ALPS1B, APL, Apoptosis (APO 1) antigen ligand 1, apoptosis (APO-1) antigen ligand 1, Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand), apoptosis antigen ligand, APT1LG1, APTL, CD178, CD178 antigen, CD95 ligand, CD95 ligand protein;Generalized lymphoproliferative disease (Gld), Cd95l, CD95-L, CD95L protein, fas antigen ligand, Fas ligand, Fas ligand (TNF superfamily, member 6), Fasl, Fas-L, FasL ICD, FasL intracellular domain, Faslg, Fas-LG, generalized lymphoproliferative disease, gld, mutant tumor necrosis factor family member 6, Receptor-binding FasL ectodomain, sFasL, Soluble Fas ligand, soluble form, SPA, SPPL2A-processed FasL form, TNFL, Tnfsf6, TNLG1A, Tumor necrosis factor (ligand) superfamily member 6, Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand), Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand), Tumor necrosis factor ligand, tumor necrosis factor ligand 1A, tumor necrosis factor ligand superfamily member 6, Tumor necrosis factor ligand superfamily member 6 (TNFL6 / TNFSF6), Tumor necrosis factor ligand superfamily member 6, membrane form, Tumor necrosis factor ligand superfamily member 6, soluble form
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 356
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P48023
Gene Symbols: Faslg
Immunogen: Recombinant protein corresponding to Human FASLG
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen: RBL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RBL1
Gene Alias: 107 kDa retinoblastoma-associated protein, AW547426, CP107, DNA-binding protein RFX5, MGC40006, p107, pRb1, RB transcriptional corepressor like 1, Rbl1, Regulatory factor X 5, regulatory factor X, 5 (influences HLA class II expression), regulatory factor X5, retinoblastoma-like 1, retinoblastoma-like 1 (p107), retinoblastoma-like protein 1, RFX5
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5933
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P28749
Gene Symbols: RBL1
Immunogen: Recombinant protein corresponding to Human RBL1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen: CENPQ
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CENPQ
Gene Alias: C6orf139; CENPQ; CENP-Q; Centromere protein Q
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55166
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q7L2Z9
Gene Symbols: CENPQ
Immunogen: Recombinant protein corresponding to Human CENPQ
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
