PIPA584298
NLK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA584298-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA584298 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
NLK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NLK
Gene Alias
AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
51701
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9UBE8
Gene Symbols
NLK
Immunogen
Recombinant protein corresponding to Human NLK
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: AAATVKAHHH QHSHHPQQQL DIEPDRPIGY GAFGVVWSVT DPRDGKRVAL KKMPNVFQNL VSCK NLK is a serine/threonine kinase involved in signal transduction and cellular communication
- Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2
- Activation of this pathway causes binding to and phosphorylation of the histone methyltransferase SETDB1
- The NLK-SETDB1 complex subsequently interacts with PPARG, leading to methylation of PPARG target promoters at histone H3K9 and transcriptional silencing
- The resulting loss of PPARG target gene transcription inhibits adipogenesis and promotes osteoblastogenesis in mesenchymal stem cells (MSCs)
- Negative regulator of the canonical Wnt/beta-catenin signaling pathway
- Binds to and phosphorylates TCF7L2/TCF4 and LEF1, promoting the dissociation of the TCF7L2/LEF1/beta-catenin complex from DNA, as well as the ubiquitination and subsequent proteolysis of LEF1
- Together these effects inhibit the transcriptional activation of canonical Wnt/beta-catenin target genes
- Negative regulator of the Notch signaling pathway
- Binds to and phosphorylates NOTCH1, thereby preventing the formation of a transcriptionally active ternary complex of NOTCH1, RBPJ/RBPSUH and MAML1
- Negative regulator of the MYB family of transcription factors.
Compare Similar Items
Show Difference
Antigen: NLK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NLK
Gene Alias: AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51701
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9UBE8
Gene Symbols: NLK
Immunogen: Recombinant protein corresponding to Human NLK
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NLK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NLK
Gene Alias:
AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51701
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9UBE8
Gene Symbols:
NLK
Immunogen:
Recombinant protein corresponding to Human NLK
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SRSF5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SRSF5
Gene Alias: Cl-4; Delayed-early protein HRS; Hrs; Insulin-induced growth response protein CL-4; pre-mRNA-splicing factor SRP40; serine and arginine rich splicing factor 5; serine/arginine-rich splicing factor 5; SFRS5; splicing factor arginine/serine-rich 5 (SRp40 HRS); splicing factor, arginine/serine-rich 5; splicing factor, arginine/serine-rich 5 (SRp40, HRS); SR splicing factor 5; SRp40; Srsf5
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6430
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q13243
Gene Symbols: SRSF5
Immunogen: Recombinant protein corresponding to Human SRSF5
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SRSF5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SRSF5
Gene Alias:
Cl-4; Delayed-early protein HRS; Hrs; Insulin-induced growth response protein CL-4; pre-mRNA-splicing factor SRP40; serine and arginine rich splicing factor 5; serine/arginine-rich splicing factor 5; SFRS5; splicing factor arginine/serine-rich 5 (SRp40 HRS); splicing factor, arginine/serine-rich 5; splicing factor, arginine/serine-rich 5 (SRp40, HRS); SR splicing factor 5; SRp40; Srsf5
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6430
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q13243
Gene Symbols:
SRSF5
Immunogen:
Recombinant protein corresponding to Human SRSF5
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: RBL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RBL1
Gene Alias: 107 kDa retinoblastoma-associated protein, AW547426, CP107, DNA-binding protein RFX5, MGC40006, p107, pRb1, RB transcriptional corepressor like 1, Rbl1, Regulatory factor X 5, regulatory factor X, 5 (influences HLA class II expression), regulatory factor X5, retinoblastoma-like 1, retinoblastoma-like 1 (p107), retinoblastoma-like protein 1, RFX5
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5933
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P28749
Gene Symbols: RBL1
Immunogen: Recombinant protein corresponding to Human RBL1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RBL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RBL1
Gene Alias:
107 kDa retinoblastoma-associated protein, AW547426, CP107, DNA-binding protein RFX5, MGC40006, p107, pRb1, RB transcriptional corepressor like 1, Rbl1, Regulatory factor X 5, regulatory factor X, 5 (influences HLA class II expression), regulatory factor X5, retinoblastoma-like 1, retinoblastoma-like 1 (p107), retinoblastoma-like protein 1, RFX5
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5933
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P28749
Gene Symbols:
RBL1
Immunogen:
Recombinant protein corresponding to Human RBL1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ZMAT4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZMAT4
Gene Alias: 9630048M01Rik, SDP1, zinc finger matrin-type 4, zinc finger matrin-type protein 4, zinc finger, matrin type 4, zinc finger, matrin-type 4, Zmat4
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79698
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q9H898
Gene Symbols: ZMAT4
Immunogen: Recombinant protein corresponding to Human ZMAT4
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ZMAT4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZMAT4
Gene Alias:
9630048M01Rik, SDP1, zinc finger matrin-type 4, zinc finger matrin-type protein 4, zinc finger, matrin type 4, zinc finger, matrin-type 4, Zmat4
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79698
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q9H898
Gene Symbols:
ZMAT4
Immunogen:
Recombinant protein corresponding to Human ZMAT4
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG