PIPA584386
STAT3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA584386-Each-of-1 | In Stock | ₹ 50,052.60 |
PIPA584386 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,052.60
GST (18%): ₹ 9,009.468
Total Price: ₹ 59,062.068
Antigen
STAT3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STAT3
Gene Alias
1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6774
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
0.10 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P40763
Gene Symbols
STAT3
Immunogen
Recombinant protein corresponding to Human STAT3
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: EKPMEIARIV ARCLWEESRL LQTAATAAQQ GGQANHPTAA VVTEKQQMLE QHLQDVRKRV QDLEQKMKVV ENLQDDFDFN YKTLKSQGDM QDLNGNNQSV TRQKMQQLEQ MLTALDQMRR SIVSELAGLL SAMEYVQK STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
- Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
- STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
- Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
- In humans, the STAT3 gene is located on the q arm of chromosome 17
- STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
- The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
- STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
- The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
- Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
- Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.
Compare Similar Items
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Antigen: STAT3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT3
Gene Alias: 1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6774
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.10 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P40763
Gene Symbols: STAT3
Immunogen: Recombinant protein corresponding to Human STAT3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
STAT3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT3
Gene Alias:
1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6774
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.10 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P40763
Gene Symbols:
STAT3
Immunogen:
Recombinant protein corresponding to Human STAT3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CMPK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cmpk1
Gene Alias: 0610011D08Rik; CK; CK {ECO:0000255; CMK; Cmpk; CMPK1; cytidine monophosphate (UMP-CMP) kinase 1; cytidine monophosphate (UMP-CMP) kinase 1, cytosolic; cytidine monophosphate kinase; cytidine/uridine monophosphate kinase 1; cytidylate kinase; cytidylate kinase 1; dCMP kinase; dCMP kinase {ECO:0000255; deoxycytidylate kinase; deoxycytidylate kinase {ECO:0000255; EC 2.7.4.14; HAMAP-Rule:MF_03172}; KCY; likely ortholog of H. sapiens UMP-CMP kinase (UMP-CMPK); nucleoside-diphosphate kinase; nucleoside-diphosphate kinase {ECO:0000255; RGD1310116; RP11-511I2.1; Uck; Umk; UMP/CMP kinase; UMP/CMP kinase {ECO:0000255; UMP/CMPK; UMP/CMPK {ECO:0000255; ump-cmp; UMP-CMP kinase; UMP-CMP kinase {ECO:0000255; UMP-CMP kinase 1; UMP-CMPk; UMPK; uridine monophosphate kinase; uridine monophosphate/cytidine monophosphate kinase; uridine monophosphate/cytidine monophosphate kinase {ECO:0000255
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51727
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: Lot-Specific
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P30085
Gene Symbols: Cmpk1
Immunogen: Recombinant protein corresponding to Human CMPK1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CMPK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cmpk1
Gene Alias:
0610011D08Rik; CK; CK {ECO:0000255; CMK; Cmpk; CMPK1; cytidine monophosphate (UMP-CMP) kinase 1; cytidine monophosphate (UMP-CMP) kinase 1, cytosolic; cytidine monophosphate kinase; cytidine/uridine monophosphate kinase 1; cytidylate kinase; cytidylate kinase 1; dCMP kinase; dCMP kinase {ECO:0000255; deoxycytidylate kinase; deoxycytidylate kinase {ECO:0000255; EC 2.7.4.14; HAMAP-Rule:MF_03172}; KCY; likely ortholog of H. sapiens UMP-CMP kinase (UMP-CMPK); nucleoside-diphosphate kinase; nucleoside-diphosphate kinase {ECO:0000255; RGD1310116; RP11-511I2.1; Uck; Umk; UMP/CMP kinase; UMP/CMP kinase {ECO:0000255; UMP/CMPK; UMP/CMPK {ECO:0000255; ump-cmp; UMP-CMP kinase; UMP-CMP kinase {ECO:0000255; UMP-CMP kinase 1; UMP-CMPk; UMPK; uridine monophosphate kinase; uridine monophosphate/cytidine monophosphate kinase; uridine monophosphate/cytidine monophosphate kinase {ECO:0000255
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51727
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P30085
Gene Symbols:
Cmpk1
Immunogen:
Recombinant protein corresponding to Human CMPK1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: BMP-2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BMP2
Gene Alias: 2610024H22Rik, AI467020, AL117858, AW546137, BB189135, BDA2, BMP, BMP2, BMP-2, BMP2A, BMP-2A, BMPRII, BMPR-II, Bone morphogenetic protein, Bone morphogenetic protein 2, bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A), bone morphogenetic protein 2A, H-BMP-2, morphogen
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 650
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot, Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P12643
Gene Symbols: BMP2
Immunogen: Recombinant protein corresponding to Human BMP2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
BMP-2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BMP2
Gene Alias:
2610024H22Rik, AI467020, AL117858, AW546137, BB189135, BDA2, BMP, BMP2, BMP-2, BMP2A, BMP-2A, BMPRII, BMPR-II, Bone morphogenetic protein, Bone morphogenetic protein 2, bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A), bone morphogenetic protein 2A, H-BMP-2, morphogen
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
650
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P12643
Gene Symbols:
BMP2
Immunogen:
Recombinant protein corresponding to Human BMP2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: GTPBP8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GTPBP8
Gene Alias: GTP binding protein 8 (putative), GTP-binding protein 8, GTP-binding protein 8 (putative), GTPBP8, HSPC135
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29083
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q8N3Z3
Gene Symbols: GTPBP8
Immunogen: Recombinant protein corresponding to Human GTPBP8
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GTPBP8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GTPBP8
Gene Alias:
GTP binding protein 8 (putative), GTP-binding protein 8, GTP-binding protein 8 (putative), GTPBP8, HSPC135
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29083
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q8N3Z3
Gene Symbols:
GTPBP8
Immunogen:
Recombinant protein corresponding to Human GTPBP8
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG