PIPA584748
ATM Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA584748-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA584748 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
ATM
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ATM
Gene Alias
AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; Ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; Atm; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
472
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q13315
Gene Symbols
ATM
Immunogen
Recombinant protein corresponding to Human ATM
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: LTIVEVLLYD PLFDWTMNPL KALYLQQRPE DETELHPTLN ADDQECKRNL SDIDQSFNKV AERVLMRLQE KLKGVE Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family
- Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer
- The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily
- ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1
- The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens
- The ATM’s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases)
- Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation
- AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction
- Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair
- Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.
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Antigen: ATM
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ATM
Gene Alias: AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; Ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; Atm; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 472
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q13315
Gene Symbols: ATM
Immunogen: Recombinant protein corresponding to Human ATM
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ATM
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ATM
Gene Alias:
AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; Ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; Atm; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
472
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q13315
Gene Symbols:
ATM
Immunogen:
Recombinant protein corresponding to Human ATM
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TDRD3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TDRD3
Gene Alias: 4732418C03Rik, 6720468N18, Tdrd3, tudor domain containing 3, tudor domain-containing protein 3
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 81550
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q9H7E2
Gene Symbols: TDRD3
Immunogen: Recombinant protein corresponding to Human TDRD3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TDRD3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TDRD3
Gene Alias:
4732418C03Rik, 6720468N18, Tdrd3, tudor domain containing 3, tudor domain-containing protein 3
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
81550
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q9H7E2
Gene Symbols:
TDRD3
Immunogen:
Recombinant protein corresponding to Human TDRD3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NOTCH1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Notch1
Gene Alias: 9930111A19Rik, AOS5, AOVD1, Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila), hN1, lin-12, major type A protein, Mis6, Motch, Motch A, mT14, N1, neurogenic locus notch homolog protein 1, NEXT, NICD, NOTCH, notch 1, Notch 1 extracellular truncation, Notch 1 intracellular domain, Notch gene homolog 1, Notch homolog 1, translocation-associated, notch receptor 1, Notch1, p300, RP23-306D20.12, RP23-306D20.12-001, Tan1, Translocation-associated notch protein TAN-1, transmembrane receptor Notch1
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4851
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P46531
Gene Symbols: Notch1
Immunogen: Recombinant protein corresponding to Human NOTCH1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NOTCH1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Notch1
Gene Alias:
9930111A19Rik, AOS5, AOVD1, Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila), hN1, lin-12, major type A protein, Mis6, Motch, Motch A, mT14, N1, neurogenic locus notch homolog protein 1, NEXT, NICD, NOTCH, notch 1, Notch 1 extracellular truncation, Notch 1 intracellular domain, Notch gene homolog 1, Notch homolog 1, translocation-associated, notch receptor 1, Notch1, p300, RP23-306D20.12, RP23-306D20.12-001, Tan1, Translocation-associated notch protein TAN-1, transmembrane receptor Notch1
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4851
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P46531
Gene Symbols:
Notch1
Immunogen:
Recombinant protein corresponding to Human NOTCH1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: KRT82
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KRT82
Gene Alias: hard keratin, type II, 2, HB2, Hb-2, K82, Kb22, keratin 82, keratin 82, type II, keratin complex 2, basic, gene 20, keratin, hair, basic, 2, keratin, type II cuticular Hb2, Keratin-82, Krt2-20, Krt82, Krthb2, Type II hair keratin Hb2, type II keratin Kb22, type-II keratin Kb22
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3888
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.4 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q9NSB4
Gene Symbols: KRT82
Immunogen: Recombinant protein corresponding to Human KRT82
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
KRT82
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KRT82
Gene Alias:
hard keratin, type II, 2, HB2, Hb-2, K82, Kb22, keratin 82, keratin 82, type II, keratin complex 2, basic, gene 20, keratin, hair, basic, 2, keratin, type II cuticular Hb2, Keratin-82, Krt2-20, Krt82, Krthb2, Type II hair keratin Hb2, type II keratin Kb22, type-II keratin Kb22
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3888
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.4 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q9NSB4
Gene Symbols:
KRT82
Immunogen:
Recombinant protein corresponding to Human KRT82
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG