PIPA585081

LC3B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA585081-Each-of-1 In Stock ₹ 44,705.10

PIPA585081 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

LC3B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP1LC3B2

Gene Alias

1010001C15Rik, Atg8, ATG8E, ATG8F, ATG8G, Autophagy-related protein LC3 B, autophagy-related ubiquitin-like modifier LC3 B, LC3, LC3 beta, LC3A, LC3B, light chain 3, MAP1 light chain 3-like protein 2, MAP1A/1B light chain 3 B, MAP1A/1BLC3, MAP1A/MAP1B LC3 A, MAP1A/MAP1B LC3 B, MAP1A/MAP1B light chain 3 B, Map1alc3, MAP1BLC3, MAP1LC3, MAP1LC3A, MAP1LC3B, MAP1LC3B2, MAP1LC3B-a, microtubule associated protein 1 light chain 3 beta, microtubule associated protein 1 light chain 3 beta 2, microtubule-associated protein 1 light chain 3, microtubule-associated protein 1 light chain 3 beta, microtubule-associated protein 1 light chain 3 beta 2, microtubule-associated proteins 1A/1B light chain 3, microtubule-associated proteins 1A/1B light chain 3 beta 2, Microtubule-associated proteins 1A/1B light chain 3B, Microtubule-associated proteins 1A/1B light chain 3B-like, Microtubule-associated proteins 1A/1B light chain 3B-like protein, Mpl3, RP11-346K17.1, wu:fb60g11, zbs559, zgc:56434

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100359928, 643246, 64862, 67443, 81631

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.

A6NCE7, Q62625, Q9CQV6, Q9GZQ8

Gene Symbols

MAP1LC3B, MAP1LC3B2

Immunogen

Full length rat LC3B Recombinant protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Keep as concentrated solution
  • Predicted reactivity: Human (96%), Mouse (99%), Rat (100%), Zebrafish (95%), Japanese Medaka (88%), Xenopus laevis (94%), Pig (95%), Chicken (92%), Rhesus Monkey (96%), Chimpanzee (96%), Bovine (95%)
  • Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS, PC-3, U87-MG, SK-N-SH, Rat brain, mouse brain
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • LC3B (Autophagy Marker Light Chain 3B, MAP1A/MAP1B LC3 B) in humans, is encoded by the gene MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B)
  • LC3B is associated with microtubule assembly and important is in neurogenesis
  • Recent studies indicate that LC3B plays a vital role in autophagy, a process that involves the bulk degradation of cytoplasmic component
  • Three human LC3 isoforms undergo post-translational modifications during autophagy
  • Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation
  • Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole)
  • LC3B is a microtubule-associated protein that mediate the physical interactions between microtubules and components of the cytoskeleton
  • LC3B may play a role in processes involving cancer, aging, metabolic and neurodegenerative disorders and cardiovascular/pulmonary diseases.

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Img

Thermo Scientific

PIPA585081

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Antigen:
LC3B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP1LC3B2

Gene Alias:
1010001C15Rik, Atg8, ATG8E, ATG8F, ATG8G, Autophagy-related protein LC3 B, autophagy-related ubiquitin-like modifier LC3 B, LC3, LC3 beta, LC3A, LC3B, light chain 3, MAP1 light chain 3-like protein 2, MAP1A/1B light chain 3 B, MAP1A/1BLC3, MAP1A/MAP1B LC3 A, MAP1A/MAP1B LC3 B, MAP1A/MAP1B light chain 3 B, Map1alc3, MAP1BLC3, MAP1LC3, MAP1LC3A, MAP1LC3B, MAP1LC3B2, MAP1LC3B-a, microtubule associated protein 1 light chain 3 beta, microtubule associated protein 1 light chain 3 beta 2, microtubule-associated protein 1 light chain 3, microtubule-associated protein 1 light chain 3 beta, microtubule-associated protein 1 light chain 3 beta 2, microtubule-associated proteins 1A/1B light chain 3, microtubule-associated proteins 1A/1B light chain 3 beta 2, Microtubule-associated proteins 1A/1B light chain 3B, Microtubule-associated proteins 1A/1B light chain 3B-like, Microtubule-associated proteins 1A/1B light chain 3B-like protein, Mpl3, RP11-346K17.1, wu:fb60g11, zbs559, zgc:56434

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100359928, 643246, 64862, 67443, 81631

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
A6NCE7, Q62625, Q9CQV6, Q9GZQ8

Gene Symbols:
MAP1LC3B, MAP1LC3B2

Immunogen:
Full length rat LC3B Recombinant protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585083

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Antigen:
ERp57

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDIA3

Gene Alias:
58 kDa glucose-regulated protein; 58 kDa microsomal protein; 58kDa; Disulfide isomerase ER-60; endoplasmic reticulum P58; endoplasmic reticulum protein; endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER p57; ER protein 57; ER protein 60; ER60; ER-60 protease; Erp; ERp 57; ERp57; ERP57 protein; ERP60; ERp61; glucose regulated protein 58; glucose regulated protein 58kD; glucose regulated protein, 58 kDa; glucose regulated protein, 58kDa; GRP 57; GRP 58; GRP57; Grp58; grp-58; HEL-S-269; HEL-S-93n; HIP-70; HsT17083; I79_003765; oxidoreductase ERp57; p58; PDI; PDIA 3; PDIA3; PDI-Q2; phospholipase C, alpha; phospholipase C-alpha; PI PLC; PI-PLC; PLC alpha; PLC[a]; Plca; protein disulfide isomerase associated 3; protein disulfide isomerase family A member 3; protein disulfide isomerase family A, member 3; protein disulfide isomerase-associated 3; protein disulfide-isomerase A3; Q-2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14827, 2923, 29468

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P11598, P27773, P30101

Gene Symbols:
PDIA3

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ERp57.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585085

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Antigen:
RAD23A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAD23A

Gene Alias:
2310040P19Rik; AL024030; HHR23A; HR23A; MGC111083; Mhr23a; rad23; RAD23 homolog A (S. cerevisiae); RAD23 homolog A, nucleotide excision repair protein; RAD23, yeast homolog, A; RAD23A; RAD23a homolog (S. cerevisiae); UV excision repair protein RAD23 homolog A

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
19358, 5886

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen)

Concentration:
6.1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P54725, P54726

Gene Symbols:
RAD23A

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human RAD23A.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585087

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Antigen:
Survivin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Birc5

Gene Alias:
AAC-11; AP14; Api4; apoptosis inhibitor 4; Apoptosis inhibitor survivin; baculoviral IAP repeat containing 5; baculoviral IAP repeat-containing 5; baculoviral IAP repeat-containing 5 (survivin); baculoviral IAP repeat-containing protein 5; BIRC 5; BIRC5; EPR 1; EPR-1; Iap4; inhibitor of apoptosis; survivin; survivin variant 3 alpha; survivin40; SVV; TIAP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11799, 332

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O15392, O70201

Gene Symbols:
Birc5

Immunogen:
Recombinant protein encompassing a sequence within the center region of human Survivin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG