PIPA585147
CD11a Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585147-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA585147 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
CD11a
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ITGAL
Gene Alias
(p180); alpha L integrin; antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; antigen CD11A p180; CD11 antigen-like family member A; CD11a; integrin alpha L; integrin alphaL; integrin alpha-L; integrin alpha-L precursor; integrin gene promoter; integrin subunit alpha L; integrin surface receptor; integrin, alpha L; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte antigen 15; lymphocyte function associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen-1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3683
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P20701
Gene Symbols
ITGAL
Immunogen
Recombinant protein encompassing a sequence within the center region of human CD11a.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Keep as concentrated solution
- Predicted reactivity: Chimpanzee (99%)
- Positive Control: THP-1
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- CD11a (LFA-1 alpha, ITGAL) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin
- CD11a is implicated in activation of LFA-1 complex
- CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling
- CD11a is expressed on the plasma membrane of leukocytes in a low-affinity conformation
- Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of CD11a to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3
- CD11a is thus involved in interaction of various immune cells and in their tissue-specific settlement, but participates also in control of cell differentiation and proliferation and of T-cell effector functions
- Blocking of CD11a function by specific antibodies or small molecules has become an important therapeutic approach in treatment of multiple inflammatory diseases
- For example, humanized anti- CD11a antibody Efalizumab (Raptiva) is being used to interfere with T cell migration to sites of inflammation, binding of cholesterol-lowering drug simvastatin to CD11a allosteric site leads to immunomodulation and increase in lymphocytic cholinergic activity
- Two transcript variants encoding different isoforms of CD11a have been found
- Diseases associated with CD11a dysfunction include benign cephalic histiocytosis and leukocyte adhesion deficiency.
Compare Similar Items
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Antigen: CD11a
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ITGAL
Gene Alias: (p180); alpha L integrin; antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; antigen CD11A p180; CD11 antigen-like family member A; CD11a; integrin alpha L; integrin alphaL; integrin alpha-L; integrin alpha-L precursor; integrin gene promoter; integrin subunit alpha L; integrin surface receptor; integrin, alpha L; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte antigen 15; lymphocyte function associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen-1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3683
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P20701
Gene Symbols: ITGAL
Immunogen: Recombinant protein encompassing a sequence within the center region of human CD11a.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CD11a
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ITGAL
Gene Alias:
(p180); alpha L integrin; antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; antigen CD11A p180; CD11 antigen-like family member A; CD11a; integrin alpha L; integrin alphaL; integrin alpha-L; integrin alpha-L precursor; integrin gene promoter; integrin subunit alpha L; integrin surface receptor; integrin, alpha L; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte antigen 15; lymphocyte function associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen-1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3683
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P20701
Gene Symbols:
ITGAL
Immunogen:
Recombinant protein encompassing a sequence within the center region of human CD11a.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CD81
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CD81
Gene Alias: 26 kDa cell surface protein TAPA-1, CD 81 antigen, Cd81, CD81 antigen, CD81 antigen (target of antiproliferative antibody 1), CD81 molecule, CVID6, S5.7, Tapa1, Tapa-1, Target of the antiproliferative antibody 1, Tetraspanin28, tetraspanin-28, Tspan28, Tspan-28
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 975
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry (Paraffin)
Concentration: 1.01 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: P60033
Gene Symbols: CD81
Immunogen: Recombinant protein encompassing a sequence within the center region of human CD81.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CD81
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CD81
Gene Alias:
26 kDa cell surface protein TAPA-1, CD 81 antigen, Cd81, CD81 antigen, CD81 antigen (target of antiproliferative antibody 1), CD81 molecule, CVID6, S5.7, Tapa1, Tapa-1, Target of the antiproliferative antibody 1, Tetraspanin28, tetraspanin-28, Tspan28, Tspan-28
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
975
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry (Paraffin)
Concentration:
1.01 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
P60033
Gene Symbols:
CD81
Immunogen:
Recombinant protein encompassing a sequence within the center region of human CD81.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: UQCRC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Uqcrc1
Gene Alias: 1110032G10Rik, Complex III subunit 1, core protein I, Cytochrome b-c1 complex subunit 1, mitochondrial, D3S3191, hypothetical protein MGC73404, QCR1, ubiquinol--cytochrome c reductase, ubiquinol-cytochrome c reductase core I protein, ubiquinol-cytochrome c reductase core protein 1, ubiquinol-cytochrome c reductase core protein I, ubiquinol-cytochrome-c reductase complex core protein 1, UQCR1, Uqcrc1, UQCRC1 protein, zgc:73404, zgc:85750
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7384
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.: P31930
Gene Symbols: Uqcrc1
Immunogen: Recombinant protein encompassing a sequence within the center region of human UQCRC1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
UQCRC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Uqcrc1
Gene Alias:
1110032G10Rik, Complex III subunit 1, core protein I, Cytochrome b-c1 complex subunit 1, mitochondrial, D3S3191, hypothetical protein MGC73404, QCR1, ubiquinol--cytochrome c reductase, ubiquinol-cytochrome c reductase core I protein, ubiquinol-cytochrome c reductase core protein 1, ubiquinol-cytochrome c reductase core protein I, ubiquinol-cytochrome-c reductase complex core protein 1, UQCR1, Uqcrc1, UQCRC1 protein, zgc:73404, zgc:85750
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7384
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.:
P31930
Gene Symbols:
Uqcrc1
Immunogen:
Recombinant protein encompassing a sequence within the center region of human UQCRC1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: alpha-Cardiac Actin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ACTC1
Gene Alias: ACTC, Actc1, Actc-1, actin alpha cardiac, actin alpha cardiac 1, actin alpha cardiac muscle 1, actin, alpha cardiac muscle 1, Actin, alpha cardiac muscle 1, intermediate form, actin, alpha, cardiac 1, actin, alpha, cardiac muscle, actin, alpha, cardiac muscle 1, alpha-actin cardiac, alphac-actin, alpha-cardiac actin, ASD5, B-actin, cardiac muscle alpha actin 1, CMD1R, CMH11, LVNC4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11464
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.25 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.: P68033
Gene Symbols: ACTC1
Immunogen: Recombinant protein encompassing a sequence within the center region of mouse alpha Cardiac Muscle Actin.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
alpha-Cardiac Actin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ACTC1
Gene Alias:
ACTC, Actc1, Actc-1, actin alpha cardiac, actin alpha cardiac 1, actin alpha cardiac muscle 1, actin, alpha cardiac muscle 1, Actin, alpha cardiac muscle 1, intermediate form, actin, alpha, cardiac 1, actin, alpha, cardiac muscle, actin, alpha, cardiac muscle 1, alpha-actin cardiac, alphac-actin, alpha-cardiac actin, ASD5, B-actin, cardiac muscle alpha actin 1, CMD1R, CMH11, LVNC4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11464
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.25 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.:
P68033
Gene Symbols:
ACTC1
Immunogen:
Recombinant protein encompassing a sequence within the center region of mouse alpha Cardiac Muscle Actin.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG