PIPA585169
GRP78 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585169-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA585169 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
GRP78
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Hspa5
Gene Alias
78 kDa glucose-regulated protein, 78 kDa glucose-regulated protein homolog, 78-kD glucose-regulated protein precursor, AL022860, AU019543, baffled, Binding-immunoglobulin protein, bip, BiP protein, BiP/Grp78, cb865, D2Wsu141e, D2Wsu17e, Endoplasmic reticulum chaperone BiP, endoplasmic reticulum chaperone BiP, 78 kDa glucose-regulated protein, endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, epididymis secretory sperm binding protein Li 89n, fb60h09, fi36d04, FLJ26106, glucose regulated protein, 78 kDa, glucose-regulated protein, glucose-regulated protein, 78kDa, GRP 78, grp78, GRP-78, heat shock 70 kDa protein 5, heat shock 70 kDa protein 5a, heat shock 70kD protein 5, heat shock 70kD protein 5 (glucose-regulated protein, 78kD), heat shock 70kDa protein 5, heat shock 70kDa protein 5 (glucose-regulated protein), heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa), heat shock protein 5, heat shock protein 70 family protein 5, heat shock protein family A (Hsp70) member 5, heat shock protein family A (Hsp70) member 5 L homeolog, heat shock protein family A member 5, heavy-chain binding protein BiP, HEL-S-89n, Hsce70, hsp70, Hsp70 family ATPase KAR2, HSP70 family protein 5, HSPA 5, HSPA5, hspa5.L, hspa5a, I79_019946, immunoglobulin binding protein, immunoglobulin heavy chain-binding protein, Immunoglobulin heavy chain-binding protein homolog, J1248, KAR2, mBiP, MIF2, Sez7, SEZ-7, SSD1, Steroidogenesis-activator polypeptide, wu:fb60h09, wu:fi36d04, XAP-1, XAP-1 antigen, XELAEV_180384511mg, YJL034W, zgc:55994, zgc:77606
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14828, 25617, 3309
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Western Blot
Concentration
1.28 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.
P06761, P11021, P20029
Gene Symbols
Hspa5
Immunogen
Recombinant protein encompassing a sequence within the center region of human Grp78.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Keep as concentrated solution
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (98%), Japanese Medaka (97%), Xenopus laevis (97%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)
- Positive Control: 293T, A431, HeLa, HepG2, Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat2
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- GRP78 is a 78 kDa glucose regulated protein that belongs to the family of heat shock proteins that include HSP70
- GRP78 is a resident protein of the endoplasmic reticulum (ER) and associates transiently with a variety of newly synthesized secretory and membrane proteins
- GRP78 may also interact with mutant and misfolded proteins, marking them for degradation
- The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C-terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 (GRP94) and protein disulfide isomerase (PDI)
- The KDEL signal is recognized by the KDEL receptor and this interaction ensures recycling of escaped ER proteins back to the ER
- GRP78’s involvement in correct folding of proteins and degradation of misfolded proteins is via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate
- GRP78 is critical for maintenance of cell homeostasis and the prevention of apoptosis
- GRP78 protein levels have been shown to be a reliable biomarker of hypoglycemia and serves a neuroprotective function in neurons exposed to glutamate and oxidative stress
- GRP78 levels are reduced in the brains of Alzheimer's Disease patients, and decreased expression of GRP78 is found associated with missense mutations in the human presenilin-1 (PS1) gene
- Further, the induction of the GRP78 protein has been associated with the development of drug-resistance to antitumor drugs.
Compare Similar Items
Show Difference
Antigen: GRP78
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Hspa5
Gene Alias: 78 kDa glucose-regulated protein, 78 kDa glucose-regulated protein homolog, 78-kD glucose-regulated protein precursor, AL022860, AU019543, baffled, Binding-immunoglobulin protein, bip, BiP protein, BiP/Grp78, cb865, D2Wsu141e, D2Wsu17e, Endoplasmic reticulum chaperone BiP, endoplasmic reticulum chaperone BiP, 78 kDa glucose-regulated protein, endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, epididymis secretory sperm binding protein Li 89n, fb60h09, fi36d04, FLJ26106, glucose regulated protein, 78 kDa, glucose-regulated protein, glucose-regulated protein, 78kDa, GRP 78, grp78, GRP-78, heat shock 70 kDa protein 5, heat shock 70 kDa protein 5a, heat shock 70kD protein 5, heat shock 70kD protein 5 (glucose-regulated protein, 78kD), heat shock 70kDa protein 5, heat shock 70kDa protein 5 (glucose-regulated protein), heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa), heat shock protein 5, heat shock protein 70 family protein 5, heat shock protein family A (Hsp70) member 5, heat shock protein family A (Hsp70) member 5 L homeolog, heat shock protein family A member 5, heavy-chain binding protein BiP, HEL-S-89n, Hsce70, hsp70, Hsp70 family ATPase KAR2, HSP70 family protein 5, HSPA 5, HSPA5, hspa5.L, hspa5a, I79_019946, immunoglobulin binding protein, immunoglobulin heavy chain-binding protein, Immunoglobulin heavy chain-binding protein homolog, J1248, KAR2, mBiP, MIF2, Sez7, SEZ-7, SSD1, Steroidogenesis-activator polypeptide, wu:fb60h09, wu:fi36d04, XAP-1, XAP-1 antigen, XELAEV_180384511mg, YJL034W, zgc:55994, zgc:77606
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14828, 25617, 3309
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Western Blot
Concentration: 1.28 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: P06761, P11021, P20029
Gene Symbols: Hspa5
Immunogen: Recombinant protein encompassing a sequence within the center region of human Grp78.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
GRP78
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Hspa5
Gene Alias:
78 kDa glucose-regulated protein, 78 kDa glucose-regulated protein homolog, 78-kD glucose-regulated protein precursor, AL022860, AU019543, baffled, Binding-immunoglobulin protein, bip, BiP protein, BiP/Grp78, cb865, D2Wsu141e, D2Wsu17e, Endoplasmic reticulum chaperone BiP, endoplasmic reticulum chaperone BiP, 78 kDa glucose-regulated protein, endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, epididymis secretory sperm binding protein Li 89n, fb60h09, fi36d04, FLJ26106, glucose regulated protein, 78 kDa, glucose-regulated protein, glucose-regulated protein, 78kDa, GRP 78, grp78, GRP-78, heat shock 70 kDa protein 5, heat shock 70 kDa protein 5a, heat shock 70kD protein 5, heat shock 70kD protein 5 (glucose-regulated protein, 78kD), heat shock 70kDa protein 5, heat shock 70kDa protein 5 (glucose-regulated protein), heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa), heat shock protein 5, heat shock protein 70 family protein 5, heat shock protein family A (Hsp70) member 5, heat shock protein family A (Hsp70) member 5 L homeolog, heat shock protein family A member 5, heavy-chain binding protein BiP, HEL-S-89n, Hsce70, hsp70, Hsp70 family ATPase KAR2, HSP70 family protein 5, HSPA 5, HSPA5, hspa5.L, hspa5a, I79_019946, immunoglobulin binding protein, immunoglobulin heavy chain-binding protein, Immunoglobulin heavy chain-binding protein homolog, J1248, KAR2, mBiP, MIF2, Sez7, SEZ-7, SSD1, Steroidogenesis-activator polypeptide, wu:fb60h09, wu:fi36d04, XAP-1, XAP-1 antigen, XELAEV_180384511mg, YJL034W, zgc:55994, zgc:77606
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14828, 25617, 3309
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Western Blot
Concentration:
1.28 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
P06761, P11021, P20029
Gene Symbols:
Hspa5
Immunogen:
Recombinant protein encompassing a sequence within the center region of human Grp78.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: VEGF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: VEGFA
Gene Alias: angiogenic factor, etID309976.16, eVEGF120, eVEGF164, human VEGF121 homolog, MGC70609, MVCD1, ovine vascular endothelial growth factor, RP1-261G23.1, unnamed protein product, VAS, vascular endothelial growth factor, vascular endothelial growth factor (VEGF) precursor, vascular endothelial growth factor 121 isoform, vascular endothelial growth factor 164, vascular endothelial growth factor 165b, vascular endothelial growth factor 182, vascular endothelial growth factor 182 isoform, vascular endothelial growth factor 188, vascular endothelial growth factor 188 isoform, vascular endothelial growth factor 189, vascular endothelial growth factor A, vascular endothelial growth factor A121, vascular endothelial growth factor A165, vascular endothelial growth factor Aa, Vascular endothelial growth factor A-A, vascular endothelial growth factor isoform 165, vascular permeability factor, Vasculotropin, VEGF, VEGF1, VEGF164, VEGF182, VEGF188, vegfa, VEGF-A, VEGFA165b, vegfaa, VEGF-A-A, VEGFMGC70609, VPF, VPF ant, wu:fj82c06
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22339, 7422, 83785
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.17 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: P15692, P16612, Q00731
Gene Symbols: VEGFA
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human VEGF.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
VEGF
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
VEGFA
Gene Alias:
angiogenic factor, etID309976.16, eVEGF120, eVEGF164, human VEGF121 homolog, MGC70609, MVCD1, ovine vascular endothelial growth factor, RP1-261G23.1, unnamed protein product, VAS, vascular endothelial growth factor, vascular endothelial growth factor (VEGF) precursor, vascular endothelial growth factor 121 isoform, vascular endothelial growth factor 164, vascular endothelial growth factor 165b, vascular endothelial growth factor 182, vascular endothelial growth factor 182 isoform, vascular endothelial growth factor 188, vascular endothelial growth factor 188 isoform, vascular endothelial growth factor 189, vascular endothelial growth factor A, vascular endothelial growth factor A121, vascular endothelial growth factor A165, vascular endothelial growth factor Aa, Vascular endothelial growth factor A-A, vascular endothelial growth factor isoform 165, vascular permeability factor, Vasculotropin, VEGF, VEGF1, VEGF164, VEGF182, VEGF188, vegfa, VEGF-A, VEGFA165b, vegfaa, VEGF-A-A, VEGFMGC70609, VPF, VPF ant, wu:fj82c06
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22339, 7422, 83785
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.17 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
P15692, P16612, Q00731
Gene Symbols:
VEGFA
Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human VEGF.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TLR5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TLR5
Gene Alias: FLJ10052; MELIOS; MGC126430; MGC126431; RP11-239E10.1; SLE1; SLEB1; systemic lupus erythematosus susceptibility 1; TIL3; Tlr5; toll like receptor 5; Toll/interleukin-1 receptor-like protein 3; toll-like receptor 5
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7100
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: O60602
Gene Symbols: TLR5
Immunogen: Recombinant protein encompassing a sequence within the center region of human TLR5.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TLR5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TLR5
Gene Alias:
FLJ10052; MELIOS; MGC126430; MGC126431; RP11-239E10.1; SLE1; SLEB1; systemic lupus erythematosus susceptibility 1; TIL3; Tlr5; toll like receptor 5; Toll/interleukin-1 receptor-like protein 3; toll-like receptor 5
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7100
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
O60602
Gene Symbols:
TLR5
Immunogen:
Recombinant protein encompassing a sequence within the center region of human TLR5.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TNFR1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tnfrsf1a
Gene Alias: CD120a; CD120a antigen; FPF; hypothetical protein; metalloproteinase inhibitor 4; MGC19588; MS5; n-smase activation assoc. factor; p55; p55 TNF receptor; p55-R; p60; p62; p63; sCD120a; soluble CD120a; soluble TNFR1; sTNF RI; sTNFR I; sTNFR1; sTNFRI; TBP1; TBPI; TIMP metallopeptidase inhibitor 4; Timp4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4; TNF receptor alpha chain; TNF receptor superfamily member 1A; TNF-alphaR1; TNF-alpha-R1; TNFalpha-R1; TNFAR; TNFR; TNF-R; TNFR I; TNFR1; TNF-R1; Tnfr-1; TNFR1-d2; Tnfr-2; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRp55; Tnfrsf1a; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A, membrane form; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor rec
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7132
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P19438
Gene Symbols: Tnfrsf1a
Immunogen: Recombinant protein encompassing a sequence within the center region of human TNF Receptor I.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TNFR1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Tnfrsf1a
Gene Alias:
CD120a; CD120a antigen; FPF; hypothetical protein; metalloproteinase inhibitor 4; MGC19588; MS5; n-smase activation assoc. factor; p55; p55 TNF receptor; p55-R; p60; p62; p63; sCD120a; soluble CD120a; soluble TNFR1; sTNF RI; sTNFR I; sTNFR1; sTNFRI; TBP1; TBPI; TIMP metallopeptidase inhibitor 4; Timp4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4; TNF receptor alpha chain; TNF receptor superfamily member 1A; TNF-alphaR1; TNF-alpha-R1; TNFalpha-R1; TNFAR; TNFR; TNF-R; TNFR I; TNFR1; TNF-R1; Tnfr-1; TNFR1-d2; Tnfr-2; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRp55; Tnfrsf1a; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A, membrane form; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor rec
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7132
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P19438
Gene Symbols:
Tnfrsf1a
Immunogen:
Recombinant protein encompassing a sequence within the center region of human TNF Receptor I.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG