PIPA585246
IKK beta Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585246-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA585246 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
IKK beta
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ikbkb
Gene Alias
AI132552, AIM-1, FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, Ikbkb, IKK[b], IKK2, IKK-2, IKKB, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, nuclear factor NF-kappa-B inhibitor kinase beta
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3551
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Western Blot
Concentration
0.96 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.
O14920
Gene Symbols
Ikbkb
Immunogen
Recombinant protein encompassing a sequence within the center region of human IKK beta.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Keep as concentrated solution
- Predicted reactivity: Mouse (80%)
- Positive Control: Jurkat, Raji, K562, THP-1, NCI-H929, DDDDK-tagged IKBKB-transfected 293T
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex
- Inhibitor of nuclear factor kappa-B kinase subunit beta (IKK beta) is a serine kinase that plays an essential role in the NF-kaapa-B signaling pathway which is activated by mulitple stimuli such as inflammatory cytokines, bacterial, or viral products, DNA damages, or other cellular stresses
- IKK beta acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues
- These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome
- In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis
- Mutations affecting the IKK beta gene can result in Immunodeficiency 15 (IMD15).
Compare Similar Items
Show Difference
Antigen: IKK beta
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ikbkb
Gene Alias: AI132552, AIM-1, FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, Ikbkb, IKK[b], IKK2, IKK-2, IKKB, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, nuclear factor NF-kappa-B inhibitor kinase beta
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3551
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Western Blot
Concentration: 0.96 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.: O14920
Gene Symbols: Ikbkb
Immunogen: Recombinant protein encompassing a sequence within the center region of human IKK beta.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
IKK beta
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ikbkb
Gene Alias:
AI132552, AIM-1, FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, Ikbkb, IKK[b], IKK2, IKK-2, IKKB, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, nuclear factor NF-kappa-B inhibitor kinase beta
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3551
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Western Blot
Concentration:
0.96 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.:
O14920
Gene Symbols:
Ikbkb
Immunogen:
Recombinant protein encompassing a sequence within the center region of human IKK beta.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TRIM2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Trim2
Gene Alias: CMT2R, E3 ubiquitin-protein ligase TRIM2, KIAA0517, mKIAA0517, narf, Neural activity-related RING finger protein, RING finger protein 86, RING-type E3 ubiquitin transferase TRIM2, RNF86, TRIM2, tripartite motif containing 2, tripartite motif protein 2, tripartite motif protein TRIM2, tripartite motif-containing 2, tripartite motif-containing protein 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23321
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.28 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.: Q9C040
Gene Symbols: Trim2
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TRIM2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TRIM2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Trim2
Gene Alias:
CMT2R, E3 ubiquitin-protein ligase TRIM2, KIAA0517, mKIAA0517, narf, Neural activity-related RING finger protein, RING finger protein 86, RING-type E3 ubiquitin transferase TRIM2, RNF86, TRIM2, tripartite motif containing 2, tripartite motif protein 2, tripartite motif protein TRIM2, tripartite motif-containing 2, tripartite motif-containing protein 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23321
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.28 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.:
Q9C040
Gene Symbols:
Trim2
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TRIM2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: GALR1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GALR1
Gene Alias: Gal receptor 1, Gal-1 receptor, GAL1-R, Galanin r1 receptor, galanin receptor 1, galanin receptor type 1, Galanin-1 receptor, Galn1r, GALNR, Galnr1, Galr1, Gal-r1, GALR-1, Hugal 1-r
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2587
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Concentration: 0.3 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.: P47211
Gene Symbols: GALR1
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GALR1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GALR1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GALR1
Gene Alias:
Gal receptor 1, Gal-1 receptor, GAL1-R, Galanin r1 receptor, galanin receptor 1, galanin receptor type 1, Galanin-1 receptor, Galn1r, GALNR, Galnr1, Galr1, Gal-r1, GALR-1, Hugal 1-r
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2587
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Concentration:
0.3 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.:
P47211
Gene Symbols:
GALR1
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GALR1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ZO-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TJP1
Gene Alias: DKFZp686M05161, I79_005485, MGC133289, OTTHUMP00000174520, Tight junction protein 1, tight junction protein 1 (zona occludens 1), tight junction protein ZO-1, Tjp1, zo1, ZO-1, ZO-1 MDCK, zona occludens 1, zona occludens protein 1, zonula occludens 1, zonula occludens 1 protein, zonula occludens protein 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21872, 7082
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot, Immunoprecipitation, Western Blot
Concentration: 0.22 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: P39447, Q07157
Gene Symbols: TJP1
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human ZO-1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ZO-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TJP1
Gene Alias:
DKFZp686M05161, I79_005485, MGC133289, OTTHUMP00000174520, Tight junction protein 1, tight junction protein 1 (zona occludens 1), tight junction protein ZO-1, Tjp1, zo1, ZO-1, ZO-1 MDCK, zona occludens 1, zona occludens protein 1, zonula occludens 1, zonula occludens 1 protein, zonula occludens protein 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21872, 7082
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot, Immunoprecipitation, Western Blot
Concentration:
0.22 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
P39447, Q07157
Gene Symbols:
TJP1
Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human ZO-1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG