PIPA585446

EXOSC5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585446-Each-of-1 In Stock ₹ 44,191.74

PIPA585446 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

EXOSC5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EXOSC5

Gene Alias

Chronic myelogenous leukemia tumor antigen 28; CML28; D7Wsu180e; EXOSC5; Exosome complex component RRP46; exosome complex exonuclease RRP46; exosome complex exonuclease RRP46; exosome complex component RRP46; exosome component 5; exosome component Rrp46; hRrp46p; p12B; Ribosomal RNA-processing protein 46; RRP41B; RRP46; Rrp46p; si:ch211-194n6.2; Unknown (protein for MGC:153707); zgc:153707

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56915

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.35 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

Q9NQT4

Gene Symbols

EXOSC5

Immunogen

Full length human EXOSC5 Recombinant protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Keep as concentrated solution
  • Predicted reactivity: Human (99%), Mouse (91%), Rat (91%), Pig (90%)
  • Positive Control: HeLa, HeLa nuclear extract
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events
  • In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm
  • The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates
  • In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs
  • It seems to be involved in degradation of histone mRNA
  • The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes
  • [UniProt]

Compare Similar Items

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Img

Thermo Scientific

PIPA585446

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Antigen:
EXOSC5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EXOSC5

Gene Alias:
Chronic myelogenous leukemia tumor antigen 28; CML28; D7Wsu180e; EXOSC5; Exosome complex component RRP46; exosome complex exonuclease RRP46; exosome complex exonuclease RRP46; exosome complex component RRP46; exosome component 5; exosome component Rrp46; hRrp46p; p12B; Ribosomal RNA-processing protein 46; RRP41B; RRP46; Rrp46p; si:ch211-194n6.2; Unknown (protein for MGC:153707); zgc:153707

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56915

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.35 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q9NQT4

Gene Symbols:
EXOSC5

Immunogen:
Full length human EXOSC5 Recombinant protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585449

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Antigen:
Complement C3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C3

Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; C3d; complement C3; Complement C3 alpha chain; Complement C3 beta chain; complement C3 protein (GPC3) precursor; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3; complement component C3 alpha-chain; complement component C3a; complement component C3b; complement component C3d; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; I79_008227; LOC100060539; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3; Unknown (protein for MGC:134562)

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12266, 718

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P01024, P01027

Gene Symbols:
C3

Immunogen:
__

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585450

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Antigen:
beta Tubulin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tubb3

Gene Alias:
2310057H16Rik, 2810484G07Rik, 3200002H15Rik, AA408537, AI325297, AI596182, B130022C14Rik, bA631M21.2, BB220206, beta 5-tubulin, beta Ib tubulin, beta tubulin, beta tubulin 1, beta-4, beta-4 tubulin, beta-4-tubulin, beta-5, beta-5 tubulin, beta5-tubulin, betaIII-tubulin, beta-tubulin, beta-tubulin class-III, Beta-tubulin class-V, beta-tubulin class-VI, Beta-tubulin isotype I, c(beta)7 tubulin, CDCBM, CDCBM1, CDCBM5, CDCBM6, CFEOM3, CFEOM3A, class I beta tubulin, Class I beta-tubulin, class IIa beta-tubulin, class III beta-tubulin, class IVa beta-tubulin, class V beta tubulin, class V beta-tubulin, CSCSC1, dJ40E16.7, dystonia 4, torsion (autosomal dominant), DYT4, FEOM3, HSA10p15 beta-tubulin 4Q, HsT1601, hypothetical protein LOC540236, hypothetical protein LOC550458, I79_000194, I79_012097, LOC100349792, LOC100761889, LOW QUALITY PROTEIN: tubulin beta-6 chain, M(beta)1, M(beta)2, M(beta)3, M(beta)4, M(beta)5, M(beta)6, M40, M40 antibody, MGC128415 protein, MGC137802 protein, neuron-specific class III beta-tubulin, OK/SW-cl.56, OOMD, OOMD2, RGD1305887, si:ch211-122i22.4, si:ch211-9a18.2, Tubb, tubb beta-5, tubb.L, Tubb1, TUBB2, Tubb2a, tubb2a {ECO:0000250, Tubb3, TUBB4, TUBB4A, tubb5, TUBB-5, TUBB6, TUBB8, Tubulin 5 beta, tubulin beta, tubulin beta 1 class VI, tubulin beta 2A class IIa, tubulin beta 3 class III, tubulin beta 4', tubulin beta 4A class IVa, tubulin beta 6 class V, tubulin beta 8 class VIII, Tubulin beta chain, tubulin beta class I, tubulin beta class I L homeolog, Tubulin beta class IIa, Tubulin beta class V, tubulin beta MGC4083, tubulin beta-1, tubulin beta-1 chain, tubulin beta-1 chain-like, tubulin beta-2A chain, tubulin beta-2B chain, tubulin beta-3 chain, Tubulin beta-4 chain, tubulin beta-4A chain, Tubulin beta-5 chain, tubulin beta-5 chain, tubulin beta-6 chain, tubulin beta-6 chain, Tubulin beta-7 chain, tubulin beta-8 chain, Tubulin beta-III, tubulin, beta 1 class VI, tubulin, beta 2, tubulin, beta 2A, tubulin, beta 2A class IIA, tubulin, beta 3, tubulin, beta 3 class III, tubulin, beta 4, tubulin, beta 4 class IVa, tubulin, beta 4A class IVa, tubulin, beta 5, tubulin, beta 5 class I, tubulin, beta 6 class V, tubulin, beta class I, tubulin, beta family 1, tubulin, beta polypeptide, tubulin, beta polypeptide 2, tubulin, beta, 3, tubulin, beta, 4, tubulin, beta, 5, uncharacterized protein LOC550458, UniProtKB:Q7TMM9}, Unknown (protein for MGC:134115), unnamed protein product, XELAEV_18039222mg, XLOT, zbetaI, zgc:112515

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10381, 10382, 203068, 347688, 7280, 81027, 84617

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.68 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
P04350, P07437, Q13509, Q13885, Q3ZCM7, Q9BUF5, Q9H4B7

Gene Symbols:
TUBB, Tubb1, Tubb2a, Tubb3, Tubb4a, Tubb6, TUBB8

Immunogen:
Recombinant protein encompassing a sequence within the center region of human beta Tubulin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585451

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Antigen:
FBXW8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FBXW8

Gene Alias:
4930438M06Rik; F-box and WD repeat domain containing 8; F-box and WD-40 domain protein 8; F-box and WD-40 domain-containing protein 8; F-box only protein 29; F-box protein FBX29; F-box/WD repeat-containing protein 8; FBW6; FBW8; Fbx29; FBXO29; FBXW6; FBXW8; LOW QUALITY PROTEIN: F-box/WD repeat-containing protein 8; MGC33534

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26259

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q8N3Y1

Gene Symbols:
FBXW8

Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human FBXW8.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG