PIPA585481
DISC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585481-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA585481 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
DISC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DISC1
Gene Alias
C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
27185
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9NRI5
Gene Symbols
DISC1
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human DISC1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Keep as concentrated solution
- Predicted reactivity: Rhesus Monkey (95%)
- Positive Control: NT2D1, IMR32
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- DISC1 (Disrupted in Schizophrenia 1) is a multifunctional protein that interacts with multiple proteins of the centrosome and cytoskeletal system, and is involved in neuronal functions that are dependent upon proper cytoskeletal regulation, including neuronal migration, neurite architecture and intracellular transport
- Regions of the brain which express DISC1 include the hippocampus, lateral septum, amygdala, cerebral cortex, cerebellum and paraventricular hypothalamus, and loss of DISC1 function results in differences in structural organization.The DISC1 gene locus is associated with patients afflicted with schizophrenia as a result of chromosomal translocations
- DISC-1 encodes a large protein predicted to contain a globular N-terminal domain and a helical C-terminal domain, both of which have the potential to form interactions with other proteins
- DISC-1 interacts with proteins involved in the centrosome and cytoskeletal system, including MIPT3, MAP1A and NUDEL; proteins which localize receptors to membranes, including alpha-actinin 2, beta 4-spectrin; and proteins which transduce signals from membrane receptors, including ATF-4 and ATF-5
- Therefore, DISC-1 is thought to be involved in intracellular transport, neurite architecture and/or neuronal migration, all of which are thought to be pathogenic in the schizophrenic brain
- Decreased expression of DISC1 in neurons caused an accelerated rate of neuronal integration, resulting in aberrant morphological development, suggesting that DISC1 plays a role in dendritic development and synapse formation
- DISC-1 is thought to be involved in intracellular transport, neurite architecture and/or neuronal migration, all of which are thought to be pathogenic in the schizophrenic brain.
Compare Similar Items
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Antigen: DISC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DISC1
Gene Alias: C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27185
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9NRI5
Gene Symbols: DISC1
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human DISC1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DISC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DISC1
Gene Alias:
C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27185
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9NRI5
Gene Symbols:
DISC1
Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human DISC1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CPEB1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CPEB1
Gene Alias: AU024112; CEBP; Cpeb; CPEB1; CPEB-1; CPE-binding protein 1; CPE-BP1; cytoplasmic polyadenylation element binding protein 1; cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; h-CPEB; hCPEB-1; mCPEB; mCPEB-1; MGC34136; MGC60106
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 64506
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9BZB8
Gene Symbols: CPEB1
Immunogen: Recombinant protein encompassing a sequence within the center region of human CPEB1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CPEB1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CPEB1
Gene Alias:
AU024112; CEBP; Cpeb; CPEB1; CPEB-1; CPE-binding protein 1; CPE-BP1; cytoplasmic polyadenylation element binding protein 1; cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; h-CPEB; hCPEB-1; mCPEB; mCPEB-1; MGC34136; MGC60106
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
64506
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9BZB8
Gene Symbols:
CPEB1
Immunogen:
Recombinant protein encompassing a sequence within the center region of human CPEB1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TMEM108
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMEM108
Gene Alias: AI462967, B130017P16Rik, cancer/testis antigen 124, CT124, KIAA1690, R74726, retrolinkin, RGD1311530, RTLN, TMEM108, Transmembrane protein 108, UNQ1875/PRO4318
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 66000
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.8 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.: Q6UXF1
Gene Symbols: TMEM108
Immunogen: Recombinant protein encompassing a sequence within the center region of human TMEM108.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TMEM108
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMEM108
Gene Alias:
AI462967, B130017P16Rik, cancer/testis antigen 124, CT124, KIAA1690, R74726, retrolinkin, RGD1311530, RTLN, TMEM108, Transmembrane protein 108, UNQ1875/PRO4318
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
66000
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.8 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.:
Q6UXF1
Gene Symbols:
TMEM108
Immunogen:
Recombinant protein encompassing a sequence within the center region of human TMEM108.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: LRRC59
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Lrrc59
Gene Alias: AA959742, C78668, hypothetical protein PRO1855, leucine rich repeat containing 59, leucine-rich repeat-containing protein 59, Leucine-rich repeat-containing protein 59, N-terminally processed, leucine-rich repeat-containing protein 59, LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 59, LRRC59, p34, PRO1855, Protein p34, Rbp34, Ribosome-binding protein p34
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55379, 98238
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.: Q922Q8, Q96AG4
Gene Symbols: Lrrc59
Immunogen: Recombinant protein encompassing a sequence within the center region of human LRRC59.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
LRRC59
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Lrrc59
Gene Alias:
AA959742, C78668, hypothetical protein PRO1855, leucine rich repeat containing 59, leucine-rich repeat-containing protein 59, Leucine-rich repeat-containing protein 59, N-terminally processed, leucine-rich repeat-containing protein 59, LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 59, LRRC59, p34, PRO1855, Protein p34, Rbp34, Ribosome-binding protein p34
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
55379, 98238
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.:
Q922Q8, Q96AG4
Gene Symbols:
Lrrc59
Immunogen:
Recombinant protein encompassing a sequence within the center region of human LRRC59.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG