SHANK3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585760-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA585760 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
SHANK3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Shank3
Gene Alias
AI841104; DEL22q13.3; Kiaa1650; proline rich synapse associated protein 2; proline-rich synapse-associated protein 2; PROSAP2; PSAP2; SCZD15; SH3 and multiple ankyrin repeat domains 3; SH3 and multiple ankyrin repeat domains protein 3; SH3 and multiple ankyrin repeat domains protein 3 variant c-3; SH3 and multiple ankyrin repeat domains protein 3 variant c-4; SH3 and multiple ankyrin repeat domains-like protein 3 variant 1; SH3 and multiple ankyrin repeat domains-like protein 3 variant 2; SH3 and multiple ankyrin repeat domains-like protein 3 variant 3; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-3; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-2; SH3/ankyrin domain gene 3; shank postsynaptic density protein; Shank postsynaptic density protein 3a; SHANK3; shank3 splice variant II; shank3 splice variant III; shank3 splice variant IV; Shank3b; SHANK3c-3; SHANK3c-4; shank3e splice variant III; shank3e splice variant IV; SPANK 2; SPANK2; SPANK-2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
58234, 59312
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Concentration
0.39 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
Q4ACU6, Q9JLU4
Gene Symbols
Shank3
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse SHANK3.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Keep as concentrated solution
- Predicted reactivity: Mouse (100%), Rat (100%)
- Positive Control: mouse brain, rat brain
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- SHANK3 is a major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance
- It interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton
- SHANK3 plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters
- By way of this control of actin dynamics, SHANK3 participates in the regulation of developing neurons growth cone motility and the NMDA receptor-signaling
- It also modulates GRIA1 exocytosis and GRM5/MGLUR5 expression and signaling to control the AMPA and metabotropic glutamate receptor-mediated synaptic transmission and plasticity
- SHANK3 may be required at an early stage of synapse formation and be inhibited by IGF1 to promote synapse maturation
- (Uniprot)
Compare Similar Items
Show Difference
Antigen: SHANK3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Shank3
Gene Alias: AI841104; DEL22q13.3; Kiaa1650; proline rich synapse associated protein 2; proline-rich synapse-associated protein 2; PROSAP2; PSAP2; SCZD15; SH3 and multiple ankyrin repeat domains 3; SH3 and multiple ankyrin repeat domains protein 3; SH3 and multiple ankyrin repeat domains protein 3 variant c-3; SH3 and multiple ankyrin repeat domains protein 3 variant c-4; SH3 and multiple ankyrin repeat domains-like protein 3 variant 1; SH3 and multiple ankyrin repeat domains-like protein 3 variant 2; SH3 and multiple ankyrin repeat domains-like protein 3 variant 3; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-3; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-2; SH3/ankyrin domain gene 3; shank postsynaptic density protein; Shank postsynaptic density protein 3a; SHANK3; shank3 splice variant II; shank3 splice variant III; shank3 splice variant IV; Shank3b; SHANK3c-3; SHANK3c-4; shank3e splice variant III; shank3e splice variant IV; SPANK 2; SPANK2; SPANK-2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 58234, 59312
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Concentration: 0.39 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q4ACU6, Q9JLU4
Gene Symbols: Shank3
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse SHANK3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen: SLC6A1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SLC6A1
Gene Alias: A730043E01, GABA T1, GABA T-1, GABA transporter 1, GABA transporter protein, GABAT1, GABATHG, GABATR, Gabt, GABT1, gamma-aminobutyric acid (GABA-A) transporter 1, GAT1, GAT-1, MAE, SLC6A1, Sodium- and chloride-dependent GABA transporter 1, solute carrier family 6 (neurotransmitter transporter), member 1, solute carrier family 6 (neurotransmitter transporter, GABA), member 1, solute carrier family 6 member 1, XT-1, Xtrp1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 232333, 79212
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.53 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: P23978, P31648
Gene Symbols: SLC6A1
Immunogen: Recombinant protein encompassing a sequence within the center region of mouse GABA Transporter 1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen: Nkx2.5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Nkx2-5
Gene Alias: Cardiac-specific homeobox, cardiac-specific homeobox 1, CHNG5, CSX, CSX1, Drosophila NK2 transcription factor related, locus 5, FLJ52202, FLJ97166, FLJ97195, FLJ97197, FLJ99536, HLHS2, Homeobox protein CSX, homeobox protein NK-2 homolog E, homeobox protein NKX 2-5, homeobox protein Nkx-2.5, NK2 homeobox 5, NK2 transcription factor related locus 5, NK2 transcription factor related, locus 5, NKX 2-5, NKX2.5, Nkx-2.5, Nkx-25, NKX2-5, NKX2E, NKX4-1, rNKx-2.5, tinman, tinman paralog, VSD3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114109, 1482, 18091
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.9 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: O35767, P42582, P52952
Gene Symbols: Nkx2-5
Immunogen: Recombinant protein encompassing a sequence within the center region of mouse Nkx2.5.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
