PIPA585831

ErbB4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585831-Each-of-1 In Stock ₹ 44,705.10

PIPA585831 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ErbB4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ERBB4

Gene Alias

4ICD, ALS19, avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4, avian erythroblastosis oncogene B 4, c-erbB-4, erb-b2 receptor tyrosine kinase 4, Erbb4, ERBB4 intracellular domain, ERBB4 transcript variant I12DEL, ERBB4 transcript variant I20DEL, Her4, human epidermal growth factor receptor 4, Mer4, OTTHUMP00000209432, p180erbB4, proto-oncogene-like protein c-ErbB-4, receptor tyrosine kinase, receptor tyrosine-protein kinase erbB-4, s80HER4, Tyro-2, Tyrosine kinase-type cell surface receptor HER4, v-erb-a erythroblastic leukemia viral oncogene homolog 4, v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian), v-erb-b2 avian erythroblastic leukemia viral oncogene 4, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13869, 2066

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 1% BSA and 0.09% sodium azide, pH 7.4

Gene Accession No.

Q15303, Q61527

Gene Symbols

ERBB4

Immunogen

Synthetic peptide.

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Keep as concentrated solution
  • Positive Control: Breast carcinoma or skeletal muscle
  • Oncogene ERBB4 (HER4) is a member of the type I receptor protein tyrosine subfamily that includes EGFR, ERBB2, and ERBB3
  • ERBB4 binds and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation
  • ErbB 4 is activated by neuregulins and NTAK (neural and thymus derived activator for ErbB kinases)
  • ErbB 4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself
  • Like other protein kinases, ErbB 4 mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation
  • ErbB 4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum
  • Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDAMB-330 and MDA-MB-361
  • Expression of ErbB 4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3
  • ErbB 4 levels have been found to be elevated in certain human tumor cell lines suggesting that it may play a role in some malignancies.

Compare Similar Items

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Thermo Scientific

PIPA585831

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Antigen:
ErbB4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERBB4

Gene Alias:
4ICD, ALS19, avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4, avian erythroblastosis oncogene B 4, c-erbB-4, erb-b2 receptor tyrosine kinase 4, Erbb4, ERBB4 intracellular domain, ERBB4 transcript variant I12DEL, ERBB4 transcript variant I20DEL, Her4, human epidermal growth factor receptor 4, Mer4, OTTHUMP00000209432, p180erbB4, proto-oncogene-like protein c-ErbB-4, receptor tyrosine kinase, receptor tyrosine-protein kinase erbB-4, s80HER4, Tyro-2, Tyrosine kinase-type cell surface receptor HER4, v-erb-a erythroblastic leukemia viral oncogene homolog 4, v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian), v-erb-b2 avian erythroblastic leukemia viral oncogene 4, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13869, 2066

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 1% BSA and 0.09% sodium azide, pH 7.4

Gene Accession No.:
Q15303, Q61527

Gene Symbols:
ERBB4

Immunogen:
Synthetic peptide.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA585845

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Antigen:
HIF-2 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPAS1

Gene Alias:
basic-helix-loop-helix-PAS protein MOP2; bHLHe73; Class E basic helix-loop-helix protein 73; ECYT4; endothelial PAS domain protein 1; endothelial PAS domain protein 1b; endothelial PAS domain-containing protein 1; endothelial PAS domain-containing protein 1b; EPAS; Epas1; EPAS-1; epas1b; Hif like protein; HIF1 alpha-like factor; HIF-1-alpha-like factor; HIF-1alpha-like factor; HIF1alpha-like factor; HIF2 alpha; HIF-2 alpha; HIF2A; hif-2a; hif-2ab; HIF-2alpha; HIF-2-alpha; HIF2-alpha; HIF-related factor; HLF; HLF (HIF1alpha-like factor); HRF; hypoxia inducible factor 2 alpha; hypoxia inducible factor 2, alpha subunit; hypoxia inducible factor 2a; hypoxia inducible transcription factor 2alpha; hypoxia-inducible factor 2 alpha; hypoxia-inducible factor 2-alpha; Member of PAS protein 2; mHLF; MOP2; PAS domain-containing protein 2; PASD2; wu:fq36f01

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13819, 2034, 29452

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P97481, Q99814, Q9JHS1

Gene Symbols:
EPAS1

Immunogen:
A peptide derived from the mouse/human HIF-2 alpha.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Fish, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA585849

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Antigen:
FEN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FEN1

Gene Alias:
AW538437; DNase IV; fen1; FEN-1; fen1 {ECO:0000255; FEN-1 {ECO:0000255; Flap endonuclease 1; flap endonuclease 1 {ECO:0000255; flap structure specific endonuclease 1; flap structure-specific endonuclease 1; flap structure-specific endonuclease 1 {ECO:0000255; HAMAP-Rule:MF_03140}; hFEN-1; Maturation factor 1; maturation factor-1; MF1; RAD2

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
14156, 2237

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
whole serum diluted in PBS with no preservative; pH 7.4

Gene Accession No.:
P39748, P39749

Gene Symbols:
FEN1

Immunogen:
Recombinant full-length human FEN-1 protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA585852

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Antigen:
53BP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TP53BP1

Gene Alias:
53BP1, FLJ41424, m53BP1, MGC138366, murine p53-binding protein, p202, p53-binding protein 1, p53BP1, TDRD30, TP53, TP53-binding protein 1, Tp53bp1, transformation related protein 53 binding protein 1, transformation related protein 53 binding-protein 1, Trp53bp1, tumor protein 53-binding protein, 1, tumor protein p53 binding protein 1, tumor protein p53-binding protein, 1, tumor suppressor p53-binding protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7158

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
Q12888

Gene Symbols:
TP53BP1

Immunogen:
Synthetic peptide corresponding to the amino-terminus of h53BP1, conjugated to a carrier protein.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG