PIPA585935

ATF6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585935-Each-of-1 In Stock ₹ 44,705.10

PIPA585935 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ATF6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATF6

Gene Alias

9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; Atf6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; Atf6b; ATF6beta; ATF6-beta; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; Crebl1; Creb-related protein; CREB-RP; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1388, 22926, 304962, 406169

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

G3V909, P18850, Q99941

Gene Symbols

ATF6, ATF6B

Immunogen

Recombinant protein within Human ATF6 aa 168-392

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA586112

--

Img

Thermo Scientific

PIPA586111

--

Img

Thermo Scientific

PIPA586110

--

Img

Thermo Scientific

PIPA586463

--

Img

Thermo Scientific

PIPA586313

--

Img

Thermo Scientific

PIPA586342

--

Img

Thermo Scientific

PIPA586208

--

Img

Thermo Scientific

PIPA587020

--

Description

  • Rabbit Polyclonal Antibody ATF6 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes
  • It binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3')
  • Binding to ERSE requires binding of NF-Y to ERSE
  • ATF6 could also be involved in activation of transcription by the serum response factor
  • ATF6 exists as a homodimer and heterodimer with ATF6 beta
  • The dimer interacts with the nuclear transcription factor Y (NF-Y) trimer through direct binding to NF-Y subunit C (NF-YC)
  • It Interacts also with the transcription factors GTF2I, YY1 and SRF
  • Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus
  • The basic domain of ATF6 functions as a nuclear localization signal and the basic leucine-zipper domain is sufficient for association with the NF-Y trimer and binding to ERSE
  • During the unfolded protein response an approximately 50 kDa fragment containing the cytoplasmic transcription factor domain is released by proteolysis
  • The cleavage seems to be performed sequentially by site-1 and site-2 proteases
  • ATF6 is N-glycosylated, phosphorylated in vitro by MAPK14/P38MAPK and belongs to the bZIP family.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA585935

--


Antigen:
ATF6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATF6

Gene Alias:
9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; Atf6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; Atf6b; ATF6beta; ATF6-beta; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; Crebl1; Creb-related protein; CREB-RP; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1388, 22926, 304962, 406169

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
G3V909, P18850, Q99941

Gene Symbols:
ATF6, ATF6B

Immunogen:
Recombinant protein within Human ATF6 aa 168-392

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585936

--


Antigen:
CD71 (Transferrin Receptor)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TFRC

Gene Alias:
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
22042, 7037

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P02786, Q62351

Gene Symbols:
TFRC

Immunogen:
Recombinant protein within Human CD71 aa 463-750

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585937

--


Antigen:
KV1.4 (KCNA4)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCNA4

Gene Alias:
cardiac potassium channel; fetal skeletal muscle potassium channel; HBK4; HK1; HPCN2; HUKII; KCHAN; Kcna4; KCNA4L; KCNA8; Kv1.4; Kv4; PCN2; potassium channel 2; potassium channel, voltage gated shaker related subfamily A, member 4; potassium voltage gated channel, shaker related subfamily, member 4; potassium voltage-gated channel subfamily A member 4; potassium voltage-gated channel, shaker-related subfamily, member 4; rapidly inactivating potassium channel; RCK4; RHK1; RK3; shaker-related potassium channel Kv1.4; type A potassium channel; voltage-gated K(+) channel HuKII; Voltage-gated potassium channel HBK4; voltage-gated potassium channel HK1; Voltage-gated potassium channel subunit Kv1.4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16492, 25469, 3739

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P15385, P22459, Q61423

Gene Symbols:
KCNA4

Immunogen:
Synthetic peptide within mouse Kv14 aa 201-250

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585938

--


Antigen:
PPM1A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPM1A

Gene Alias:
2310003C21Rik; 2900017D14Rik; AI427932; AU017636; IA; MMPa-2; Mpp alpha; MPPa-1; Pp2c1; PP2CA; PP2Calpha; PP2C-alpha; PPM1A; PPPM1A; Protein phosphatase 1A; protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform; protein phosphatase 1A, magnesium dependent, alpha isoform; protein phosphatase 2C isoform alpha; Protein phosphatase IA; Protein phosphatase type 1A (formely 2C) Mg-dependent alpha isoform; Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform; protein phosphatase, Mg2+/Mn2+ dependent 1A; protein phosphatase, Mg2+/Mn2+ dependent, 1A

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
19042, 24666, 5494

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P20650, P35813, P49443

Gene Symbols:
PPM1A

Immunogen:
Recombinant protein within human PP2C alpha aa 42-330

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG