PIPA585986

IGF1R (CD221) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585986-Each-of-1 In Stock ₹ 43,592.82

PIPA585986 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

IGF1R (CD221)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IGF1R

Gene Alias

A330103N21Rik; CD221; CD221 antigen; D930020L01; hyft; IGF 1 receptor; IGF 1R; IGF1R; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3480

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P08069

Gene Symbols

IGF1R

Immunogen

Recombinant protein with Human IGF1R aa 627-952

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Rabbit Polyclonal Antibody IGF1R, also known as Insulin-like Growth Factor 1 (IGF-1) Receptor, is a receptor tyrosine kinase activated by IGF-1 and IGF-2
  • IGFR has been implicated in a variety of cancers
  • The protein is a tetramer consisting of two alpha, and two beta subunits
  • The alpha-subunits binds to insulin growth factor 1 with higher affinity than to insulin growth factor 2
  • Binding results in a conformational change, followed by autophosphorylation of IGF-1R at positions 1134, 1135, 1136
  • The activated IGF-1R in turn, causes phosphorylation of substrate proteins, followed by sequential activation of RAS, RAF, and mitogen-activated protein kinase isoforms ERK, p38, and JNK, leading to the transcription of genes that drive proliferation.

Compare Similar Items

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Img

Thermo Scientific

PIPA585986

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Antigen:
IGF1R (CD221)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGF1R

Gene Alias:
A330103N21Rik; CD221; CD221 antigen; D930020L01; hyft; IGF 1 receptor; IGF 1R; IGF1R; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3480

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P08069

Gene Symbols:
IGF1R

Immunogen:
Recombinant protein with Human IGF1R aa 627-952

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585987

--


Antigen:
GMNN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GMNN

Gene Alias:
AW546347; Gem; geminin; Geminin GMNN; geminin, DNA replication inhibitor; GMNN; MGORS6; OTTHUMP00000039393; RP3 369A17.3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
57441

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O88513

Gene Symbols:
GMNN

Immunogen:
Recombinant protein with Mouse Geminin aa 70-206

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585988

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Antigen:
GSK3 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gsk3a

Gene Alias:
2700086H06Rik; DKFZp686D0638; FA; factor A; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 alpha b; glycogen synthase kinase 3 alpha b; glycogen synthase kinase-3 alpha; glycogen synthase kinase-3 alpha; GSK3; GSK-3 alpha; GSK-3[a]; GSK-3[b]; gsk3a; gsk3ab; gsk-3-alpha; OTTHUMP00000198368; Serine/threonine-protein kinase GSK3A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2931

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P49840

Gene Symbols:
Gsk3a

Immunogen:
Synthetic peptide within Human GSK3 alpha aa 434-483

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585989

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Antigen:
MKRN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MKRN2

Gene Alias:
2610002L04Rik; C81377; HSPC070; makorin ring finger protein 2; Makorin RING zinc-finger protein 2; makorin, ring finger protein, 2; Mkrn2; Probable E3 ubiquitin-protein ligase makorin-2; RING finger protein 62; RING-type E3 ubiquitin transferase makorin-2; RNF62

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23609, 67027

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9ERV1, Q9H000

Gene Symbols:
MKRN2

Immunogen:
Synthetic peptide corresponding to Human MRKN2 aa 281-330

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG