PIPA586272
beta Arrestin 1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586272-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586272 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
beta Arrestin 1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ARRB1
Gene Alias
1200006I17Rik, ARB1, ARR1, ARRB1, ARRB1 protein, arrdc1, arrestin, arrestin 2, arrestin beta 1, arrestin beta-1, arrestin, beta 1, arrestin-2, AW208571, BARRES, beta-arrestin, beta-arrestin1, beta-arrestin-1, G430100A01Rik, Non-visual arrestin-2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
109689, 25387, 408
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P29066, P49407, Q8BWG8
Gene Symbols
ARRB1
Immunogen
Synthetic peptide, corresponding to amino acids 390-440 of Human Arrestin-beta-1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Beta Arrestin 1 is a member of a family of proteins widely expressed but especially abundant in the central nervous system
- Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling and mediates agonist-dependent desensitization and internalization of Gprotein-coupled receptors (GPCRs, e.g., beta 2-adrenergic receptor)
- After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G-protein receptor kinases (GRKs) on serine residues
- Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane
- Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1 and 2 signaling pathway.
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Antigen: beta Arrestin 1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ARRB1
Gene Alias: 1200006I17Rik, ARB1, ARR1, ARRB1, ARRB1 protein, arrdc1, arrestin, arrestin 2, arrestin beta 1, arrestin beta-1, arrestin, beta 1, arrestin-2, AW208571, BARRES, beta-arrestin, beta-arrestin1, beta-arrestin-1, G430100A01Rik, Non-visual arrestin-2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 109689, 25387, 408
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P29066, P49407, Q8BWG8
Gene Symbols: ARRB1
Immunogen: Synthetic peptide, corresponding to amino acids 390-440 of Human Arrestin-beta-1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
beta Arrestin 1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ARRB1
Gene Alias:
1200006I17Rik, ARB1, ARR1, ARRB1, ARRB1 protein, arrdc1, arrestin, arrestin 2, arrestin beta 1, arrestin beta-1, arrestin, beta 1, arrestin-2, AW208571, BARRES, beta-arrestin, beta-arrestin1, beta-arrestin-1, G430100A01Rik, Non-visual arrestin-2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
109689, 25387, 408
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P29066, P49407, Q8BWG8
Gene Symbols:
ARRB1
Immunogen:
Synthetic peptide, corresponding to amino acids 390-440 of Human Arrestin-beta-1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: BCR
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Bcr
Gene Alias: 5133400C09Rik, ABL, AI561783, AI853148, ALL, BCR, BCR activator of RhoGEF and GTPase, BCR protein, BCR, RhoGEF and GTPase activating protein, bcr/abl, BCR/FGFR1 chimera protein, BCR1, breakpoint cluster region, breakpoint cluster region homolog, breakpoint cluster region protein, c-ABL, c-abl oncogene 1, CML, D22S11, D22S662, EC 2.7.11.1, FGFR1/BCR chimera protein, JTK7, Kiaa3017, mKIAA3017, p150, PHL, renal carcinoma antigen NY-REN-26, RP11-83J21.1, v-abl
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 110279, 309696, 613
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P11274, Q6PAJ1
Gene Symbols: Bcr
Immunogen: Synthetic peptide, corresponding to amino acids 321-370 of Human Bcr.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
BCR
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Bcr
Gene Alias:
5133400C09Rik, ABL, AI561783, AI853148, ALL, BCR, BCR activator of RhoGEF and GTPase, BCR protein, BCR, RhoGEF and GTPase activating protein, bcr/abl, BCR/FGFR1 chimera protein, BCR1, breakpoint cluster region, breakpoint cluster region homolog, breakpoint cluster region protein, c-ABL, c-abl oncogene 1, CML, D22S11, D22S662, EC 2.7.11.1, FGFR1/BCR chimera protein, JTK7, Kiaa3017, mKIAA3017, p150, PHL, renal carcinoma antigen NY-REN-26, RP11-83J21.1, v-abl
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
110279, 309696, 613
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P11274, Q6PAJ1
Gene Symbols:
Bcr
Immunogen:
Synthetic peptide, corresponding to amino acids 321-370 of Human Bcr.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: GP130
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL6ST
Gene Alias: 5133400A03Rik, AA389424, Ac1055, BB405851, CD130, CD130 antigen, CDW130, D13Ertd699e, EGK_16499, Gp130, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, gp130, oncostatin M receptor, GP130-RAPS, IL-6, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6RB, IL-6R-beta, IL6R-beta, IL6ST, interleukin 6 signal transducer, interleukin 6 signal transducer (gp130, oncostatin M receptor), interleukin 6 signal transducer receptor, interleukin receptor beta chain, interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, interleukin-6 signal transducer receptor, membrane glycoprotein, membrane glycoprotein 130, membrane glycoprotein gp130, oncostatin-M receptor subunit alpha
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16195, 3572
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide, pH 7.2
Gene Accession No.: P40189, Q00560
Gene Symbols: IL6ST
Immunogen: Synthetic peptide, corresponding to amino acids 750-800 of Human gp130.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
GP130
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL6ST
Gene Alias:
5133400A03Rik, AA389424, Ac1055, BB405851, CD130, CD130 antigen, CDW130, D13Ertd699e, EGK_16499, Gp130, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, gp130, oncostatin M receptor, GP130-RAPS, IL-6, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6RB, IL-6R-beta, IL6R-beta, IL6ST, interleukin 6 signal transducer, interleukin 6 signal transducer (gp130, oncostatin M receptor), interleukin 6 signal transducer receptor, interleukin receptor beta chain, interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, interleukin-6 signal transducer receptor, membrane glycoprotein, membrane glycoprotein 130, membrane glycoprotein gp130, oncostatin-M receptor subunit alpha
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16195, 3572
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide, pH 7.2
Gene Accession No.:
P40189, Q00560
Gene Symbols:
IL6ST
Immunogen:
Synthetic peptide, corresponding to amino acids 750-800 of Human gp130.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Cdc25B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDC25B
Gene Alias: AI604853, CDC25B, CDC25HU2, Cdc25m2, cell division cycle 25B, dual specificity phosphatase Cdc25B, EC 3.1.3.48, M-phase inducer phosphatase 2, MPIP2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 994
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P30305
Gene Symbols: CDC25B
Immunogen: Synthetic peptide, corresponding to amino acids 320-370 of Human Cdc25B.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Cdc25B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDC25B
Gene Alias:
AI604853, CDC25B, CDC25HU2, Cdc25m2, cell division cycle 25B, dual specificity phosphatase Cdc25B, EC 3.1.3.48, M-phase inducer phosphatase 2, MPIP2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
994
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P30305
Gene Symbols:
CDC25B
Immunogen:
Synthetic peptide, corresponding to amino acids 320-370 of Human Cdc25B.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG