PIPA586367

BCKDK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586367-Each-of-1 In Stock ₹ 45,218.46

PIPA586367 - Each of 1

₹ 45,218.46

In Stock

Quantity

1

Base Price: ₹ 45,218.46

GST (18%): ₹ 8,139.323

Total Price: ₹ 53,357.783

Antigen

BCKDK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BCKDK

Gene Alias

[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial, AI327402, BCKDHKIN, BCKDK, BCKDKD, BCKD-kinase, BDK, branched chain alpha-ketoacid dehydrogenase kinase, branched chain ketoacid dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase, EC 2.7.11.4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10295, 12041, 29603

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

O14874, O55028, Q00972

Gene Symbols

BCKDK

Immunogen

Synthetic peptide, corresponding to amino acids 21-70 of Human BCKDK.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The second major step in the catabolism of the branched-chain amino acids, isoleucine, leucine, and valine, is irreversibly catalyzed by the branched-chain alpha-keto acid dehydrogenase complex (BCKD), an inner-mitochondrial enzyme complex composed of 3 catalytic components: a branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3)
  • The complex also contains 2 enzymes that regulated the state of activity of the BCKD complex: a kinase (BCKDK), and a phosphorylase
  • The ubiquitously expressed kinase contains 1 histidine kinase domain
  • Maple syrup urine disease (MSUD) is a pathology secondary to an enzyme defect in the catabolic pathway of leucine, isoleucine, and valine
  • Accumulation of these amino acids and their corresponding keto acids results in encephalopathy and progressive neurodegeneration in infants not treated for MSUD.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586367

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Antigen:
BCKDK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCKDK

Gene Alias:
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial, AI327402, BCKDHKIN, BCKDK, BCKDKD, BCKD-kinase, BDK, branched chain alpha-ketoacid dehydrogenase kinase, branched chain ketoacid dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase, EC 2.7.11.4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10295, 12041, 29603

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O14874, O55028, Q00972

Gene Symbols:
BCKDK

Immunogen:
Synthetic peptide, corresponding to amino acids 21-70 of Human BCKDK.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586368

--


Antigen:
AIRE

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Aire

Gene Alias:
Aire, AIRE protein, AIRE1, APECED, APECED protein, APECED protein homolog, APS1, APSI, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog, Autoimmune regulator, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy), autoimmune regulator AIRE1a, LOW QUALITY PROTEIN: autoimmune regulator, OTTHUMP00000109529, PGA1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11634, 294328, 326

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O43918, Q9Z0E3

Gene Symbols:
Aire

Immunogen:
Synthetic peptide, corresponding to amino acids 101-150 of Human AIRE.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586369

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Antigen:
Ephrin A2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EFNA2

Gene Alias:
CEK7L, CEK7-L, CEK7-ligand, EFNA2, Elf1, ELF-1, EPH related receptor tyrosine kinase ligand 6, eph-related receptor tyrosine kinase ligand 6, ephrin A2, ephrin A-2, ephrin A6, EphrinA2, ephrin-A2, Epl6, EPLG6, HEK7 ligand, HEK7-L, Lerk6, LERK-6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13637, 1943, 84358

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O43921, P52801

Gene Symbols:
EFNA2

Immunogen:
Synthetic peptide, corresponding to amino acids 11-60 of Human Ephrin-A2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586370

--


Antigen:
APRIL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFSF13

Gene Alias:
2310026N09Rik, A proliferation-inducing ligand, APRIL, CD256, TALL2, TALL-2, TNF- and APOL-related leukocyte expressed ligand 2, TNF-related death ligand 1, Tnfsf13, TNLG7B, Trdl1, TRDL-1, tumor necrosis factor (ligand) superfamily, member 13, tumor necrosis factor ligand 7B, tumor necrosis factor ligand superfamily member 13, tumor necrosis factor superfamily member 13, tumor necrosis factor-like protein ZTNF2, tumor necrosis factor-related death ligand-1, UNQ383/PRO715, ZTNF2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
287437, 69583, 8741

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O75888, Q9D777

Gene Symbols:
TNFSF13

Immunogen:
Synthetic peptide, corresponding to amino acids 151-200 of Human APRIL.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG