PIPA586388
APE1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586388-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586388 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
APE1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
APEX1
Gene Alias
AP endonuclease 1, AP endonuclease class I, AP lyase, Ape, APE1, APEN, Apex, APEX nuclease, APEX nuclease (multifunctional DNA repair enzyme) 1, APEX nuclease 1, Apex1, apurinic/a, Apurinic/apy, apurinic/apyrimidinic (abasic) endonuclease, apurinic/apyrimidinic endodeoxyribonuclease 1, apurinic/apyrimidinic endonuclease, apurinic/apyrimidinic endonuclease 1, Apurinic-apyrimidinic endonuclease 1, APX, BAP 1, BAP1, deoxyribonuclease (apurinic or apyrimidinic), DNA-(apurinic or apyrimidinic site) endonuclease, DNA-(apurinic or apyrimidinic site) lyase, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, HAP1, protein REF-1, redox factor 1, redox factor-1, REF1, REF-1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11792, 328, 79116
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P27695, P28352, P43138
Gene Symbols
APEX1
Immunogen
Synthetic peptide, corresponding to amino acids 190-240 of Human APEX1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Mammalian apurinic/apyrimidinic endonuclease (APE/ref-1) is a multifunctional, bipartite enzyme that plays an important role in numerous, cellular functions
- APE is responsible for repairing abasic sites in DNA and in regulating the redox state of other proteins that play roles in oxidative signaling, transcription factor regulation (Fos, Jun, NF-kB, Myb, HIF-1 alpha, CREB, Pax), cell cycle control (p53), and apoptosis
- The most common form of DNA damage is the creation of abasic sites which are brought about through spontaneous loss or oxidative DNA damage, through chemically initiated hydrolysis (chemotherapy), ionizing radiation, UV irradiation, oxidizing agents, and removal of modified bases by DNA glycosylases
- APE is differentially expressed during development and in different tissues
- This protein has diverse subcellular localization patterns which support the possibility of its interaction with numerous, other cellular proteins in addition to DNA repair within the nucleus
- Regulation of APE by phosphorylation is mediated, at least in part, by casein kinase II
- Increases in APE message and protein levels are observed upon the reintroduction of oxygen to hypoxic cells, and in some malignant tissue relative to normal tissue
- Decreases in APE expression have been associated with the induction of cellular apoptosis.
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Antigen: APE1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APEX1
Gene Alias: AP endonuclease 1, AP endonuclease class I, AP lyase, Ape, APE1, APEN, Apex, APEX nuclease, APEX nuclease (multifunctional DNA repair enzyme) 1, APEX nuclease 1, Apex1, apurinic/a, Apurinic/apy, apurinic/apyrimidinic (abasic) endonuclease, apurinic/apyrimidinic endodeoxyribonuclease 1, apurinic/apyrimidinic endonuclease, apurinic/apyrimidinic endonuclease 1, Apurinic-apyrimidinic endonuclease 1, APX, BAP 1, BAP1, deoxyribonuclease (apurinic or apyrimidinic), DNA-(apurinic or apyrimidinic site) endonuclease, DNA-(apurinic or apyrimidinic site) lyase, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, HAP1, protein REF-1, redox factor 1, redox factor-1, REF1, REF-1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11792, 328, 79116
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P27695, P28352, P43138
Gene Symbols: APEX1
Immunogen: Synthetic peptide, corresponding to amino acids 190-240 of Human APEX1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
APE1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APEX1
Gene Alias:
AP endonuclease 1, AP endonuclease class I, AP lyase, Ape, APE1, APEN, Apex, APEX nuclease, APEX nuclease (multifunctional DNA repair enzyme) 1, APEX nuclease 1, Apex1, apurinic/a, Apurinic/apy, apurinic/apyrimidinic (abasic) endonuclease, apurinic/apyrimidinic endodeoxyribonuclease 1, apurinic/apyrimidinic endonuclease, apurinic/apyrimidinic endonuclease 1, Apurinic-apyrimidinic endonuclease 1, APX, BAP 1, BAP1, deoxyribonuclease (apurinic or apyrimidinic), DNA-(apurinic or apyrimidinic site) endonuclease, DNA-(apurinic or apyrimidinic site) lyase, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, HAP1, protein REF-1, redox factor 1, redox factor-1, REF1, REF-1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11792, 328, 79116
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P27695, P28352, P43138
Gene Symbols:
APEX1
Immunogen:
Synthetic peptide, corresponding to amino acids 190-240 of Human APEX1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Cyclophilin F
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ppif
Gene Alias: AW457192, cyclophilin 3, cyclophilin D, Cyclophilin F, CYP3, CypD, CyP-D, CyP-F, CyP-M, mitochondrial cyclophilin, mitochondrial Cyclophilin D, mitochondrial peptidyl-prolyl cis-trans isomerase, Peptidyl-prolyl cis-trans isomerase F, peptidyl-prolyl cis-trans isomerase F, mitochondrial, peptidyl-prolyl cis-trans isomerase, mitochondrial, peptidylprolyl isomerase F, peptidylprolyl isomerase F (cyclophilin F), PPIase, PPIase F, PPIF, Rotamase F
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10105, 105675, 282819
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P29117, P30405, Q99KR7
Gene Symbols: Ppif
Immunogen: Synthetic peptide, corresponding to amino acids 91-140 of Human Cyclophilin F.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Cyclophilin F
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ppif
Gene Alias:
AW457192, cyclophilin 3, cyclophilin D, Cyclophilin F, CYP3, CypD, CyP-D, CyP-F, CyP-M, mitochondrial cyclophilin, mitochondrial Cyclophilin D, mitochondrial peptidyl-prolyl cis-trans isomerase, Peptidyl-prolyl cis-trans isomerase F, peptidyl-prolyl cis-trans isomerase F, mitochondrial, peptidyl-prolyl cis-trans isomerase, mitochondrial, peptidylprolyl isomerase F, peptidylprolyl isomerase F (cyclophilin F), PPIase, PPIase F, PPIF, Rotamase F
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10105, 105675, 282819
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P29117, P30405, Q99KR7
Gene Symbols:
Ppif
Immunogen:
Synthetic peptide, corresponding to amino acids 91-140 of Human Cyclophilin F.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ACVR1B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ACVR1B
Gene Alias: 6820432J04, activin A receptor type 1B, activin A receptor type IB, activin A receptor, type 1B, activin A receptor, type IB, activin A receptor, type II-like kinase 4, activin receptor type IB, Activin receptor type-1B, activin receptor-like kinase 4, ACTRI, ActRIB, ActR-IB, ACVR1A, Acvr1b, ACVRLK2, ACVRLK4, ALK2, Alk4, ALK-4, FOP, Serine/threonine-protein kinase receptor R2, SKR1, SKR2, TSRI
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11479, 29381, 91
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P36896, P80202, Q61271
Gene Symbols: ACVR1B
Immunogen: Synthetic peptide, corresponding to amino acids 100-150 of Human ACTR-IB.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ACVR1B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ACVR1B
Gene Alias:
6820432J04, activin A receptor type 1B, activin A receptor type IB, activin A receptor, type 1B, activin A receptor, type IB, activin A receptor, type II-like kinase 4, activin receptor type IB, Activin receptor type-1B, activin receptor-like kinase 4, ACTRI, ActRIB, ActR-IB, ACVR1A, Acvr1b, ACVRLK2, ACVRLK4, ALK2, Alk4, ALK-4, FOP, Serine/threonine-protein kinase receptor R2, SKR1, SKR2, TSRI
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11479, 29381, 91
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P36896, P80202, Q61271
Gene Symbols:
ACVR1B
Immunogen:
Synthetic peptide, corresponding to amino acids 100-150 of Human ACTR-IB.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: FEN1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FEN1
Gene Alias: AW538437, DNase IV, fen1, FEN-1, fen1 {ECO:0000255, FEN-1 {ECO:0000255, Flap endonuclease 1, flap endonuclease 1 {ECO:0000255, flap structure specific endonuclease 1, flap structure-specific endonuclease 1, flap structure-specific endonuclease 1 {ECO:0000255, HAMAP-Rule:MF_03140}, hFEN-1, Maturation factor 1, maturation factor-1, MF1, RAD2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14156, 2237, 84490
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P39748, P39749, Q5XIP6
Gene Symbols: FEN1
Immunogen: Synthetic peptide, corresponding to amino acids 100-150 of Human FEN1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
FEN1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FEN1
Gene Alias:
AW538437, DNase IV, fen1, FEN-1, fen1 {ECO:0000255, FEN-1 {ECO:0000255, Flap endonuclease 1, flap endonuclease 1 {ECO:0000255, flap structure specific endonuclease 1, flap structure-specific endonuclease 1, flap structure-specific endonuclease 1 {ECO:0000255, HAMAP-Rule:MF_03140}, hFEN-1, Maturation factor 1, maturation factor-1, MF1, RAD2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14156, 2237, 84490
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P39748, P39749, Q5XIP6
Gene Symbols:
FEN1
Immunogen:
Synthetic peptide, corresponding to amino acids 100-150 of Human FEN1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG