PIPA586405
SMAD4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586405-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586405 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
SMAD4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SMAD4
Gene Alias
AW743858, D18Wsu70e, Deleted in Pancreatic Carcinoma 4 (DPC4), deleted in pancreatic carcinoma locus 4, deletion target in pancreatic carcinoma 4, Deletion target in pancreatic carcinoma 4 homolog, DPC4, hSMAD4, JIP, MAD (mothers against decapentaplegic Drosophila) homolog 4, MAD homolog 4, MAD homolog 4 (MADH4), Madh4, mothers against decapentaplegic homolog 4, Mothers against decapentaplegic homolog 4 (MADH4), mothers against decapentaplegic, Drosophila, homolog of, 4, mothers against DPP homolog 4, MYHRS, SMAD, SMAD 4, SMAD family member 4, SMAD, mothers against DPP homolog 4, SMAD4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17128, 4089, 50554
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
O70437, P97471, Q13485
Gene Symbols
SMAD4
Immunogen
Synthetic peptide, corresponding to amino acids12-64 of Human Smad4.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Smad4 is encoded by the Smad4 gene that is located on chromosome 18 in humans
- Smad4 is also known as Smad family member 4, Sma- and Mad-related protein 4 or Mothers against decapentaplegic (MAD) homolog 4
- Smad4 contains N-terminal MH1 (MAD homology 1) and C-terminal MH2 (MAD homology 2) globular domains that are involved in DNA binding and protein interactions respectively
- Binding of the TGF-beta superfamily of ligands that includes Transforming Growth Factor -beta (TGF-beta) and bone morphogenetic protein (BMP) to its cognate receptor allows phosphorylation of Smad 1, 2, 3, 5 and 8 (R-Smad, Receptor Smad)
- This signals for heterotrimerization with Smad4 (co-Smad, co-mediator Smad) and translocation of the complex to the nucleus
- Inhibitory or antagonistic Smad (I-Smad) that includes Smad 6 and 7, interact with activated R-Smads and attenuate the signaling pathway
- Smad4 acts as a tumor suppressor protein by transcriptionally regulating its target genes such as Cyclin D1 (downregulation) and collagen (upregulation) that inhibit cell proliferation
- Dephosphorylation regulates nuclear export and nucleocytoplasmic dynamics of Smads.
Compare Similar Items
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Antigen: SMAD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMAD4
Gene Alias: AW743858, D18Wsu70e, Deleted in Pancreatic Carcinoma 4 (DPC4), deleted in pancreatic carcinoma locus 4, deletion target in pancreatic carcinoma 4, Deletion target in pancreatic carcinoma 4 homolog, DPC4, hSMAD4, JIP, MAD (mothers against decapentaplegic Drosophila) homolog 4, MAD homolog 4, MAD homolog 4 (MADH4), Madh4, mothers against decapentaplegic homolog 4, Mothers against decapentaplegic homolog 4 (MADH4), mothers against decapentaplegic, Drosophila, homolog of, 4, mothers against DPP homolog 4, MYHRS, SMAD, SMAD 4, SMAD family member 4, SMAD, mothers against DPP homolog 4, SMAD4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17128, 4089, 50554
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: O70437, P97471, Q13485
Gene Symbols: SMAD4
Immunogen: Synthetic peptide, corresponding to amino acids12-64 of Human Smad4.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SMAD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMAD4
Gene Alias:
AW743858, D18Wsu70e, Deleted in Pancreatic Carcinoma 4 (DPC4), deleted in pancreatic carcinoma locus 4, deletion target in pancreatic carcinoma 4, Deletion target in pancreatic carcinoma 4 homolog, DPC4, hSMAD4, JIP, MAD (mothers against decapentaplegic Drosophila) homolog 4, MAD homolog 4, MAD homolog 4 (MADH4), Madh4, mothers against decapentaplegic homolog 4, Mothers against decapentaplegic homolog 4 (MADH4), mothers against decapentaplegic, Drosophila, homolog of, 4, mothers against DPP homolog 4, MYHRS, SMAD, SMAD 4, SMAD family member 4, SMAD, mothers against DPP homolog 4, SMAD4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17128, 4089, 50554
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
O70437, P97471, Q13485
Gene Symbols:
SMAD4
Immunogen:
Synthetic peptide, corresponding to amino acids12-64 of Human Smad4.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TDG
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TDG
Gene Alias: C-JUN leucine zipper interactive protein JZA-3, E130317C12Rik, G/T mismatch-specific thymine DNA glycosylase, hTDG, Jza1, JZA-3, Tdg, thymine DNA glycosylase, thymine-DNA glycosylase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114521, 21665, 6996
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P56581, Q13569
Gene Symbols: TDG
Immunogen: Synthetic peptide, corresponding to amino acids 28-109 of Human TDG.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TDG
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TDG
Gene Alias:
C-JUN leucine zipper interactive protein JZA-3, E130317C12Rik, G/T mismatch-specific thymine DNA glycosylase, hTDG, Jza1, JZA-3, Tdg, thymine DNA glycosylase, thymine-DNA glycosylase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114521, 21665, 6996
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P56581, Q13569
Gene Symbols:
TDG
Immunogen:
Synthetic peptide, corresponding to amino acids 28-109 of Human TDG.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: BRD3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BRD3
Gene Alias: 2410084F24Rik, AW060456, BRD3, bromodomain containing 3, bromodomain containing 3, bromodomain-containing protein 3, bromodomain containing protein 3, bromodomain-containing 3, bromodomain-containing FSH-like protein FSRG2, Bromodomain-containing protein 3, bromodomain-containing protein 3 short isoform, Fsrg2, KIAA0043, ORFX, RING3L, RING3-like protein, RINGL3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8019
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q15059
Gene Symbols: BRD3
Immunogen: Synthetic peptide, corresponding to amino acids 614-667 of Human BRD3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
BRD3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BRD3
Gene Alias:
2410084F24Rik, AW060456, BRD3, bromodomain containing 3, bromodomain containing 3, bromodomain-containing protein 3, bromodomain containing protein 3, bromodomain-containing 3, bromodomain-containing FSH-like protein FSRG2, Bromodomain-containing protein 3, bromodomain-containing protein 3 short isoform, Fsrg2, KIAA0043, ORFX, RING3L, RING3-like protein, RINGL3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8019
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q15059
Gene Symbols:
BRD3
Immunogen:
Synthetic peptide, corresponding to amino acids 614-667 of Human BRD3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PIG3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TP53I3
Gene Alias: p53-induced gene 3 protein, PIG3, quinone oxidoreductase homolog, quinone oxidoreductase PIG3, Quinone oxidoreductase-like protein 2, RGD1304982, TP53I3, tumor protein p53 inducible protein 3, Tumor protein p53-inducible protein 3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 289138, 9540
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: B0BNC9, Q53FA7
Gene Symbols: TP53I3
Immunogen: Synthetic peptide, corresponding to amino acids 230-286 of Human PIG3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PIG3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TP53I3
Gene Alias:
p53-induced gene 3 protein, PIG3, quinone oxidoreductase homolog, quinone oxidoreductase PIG3, Quinone oxidoreductase-like protein 2, RGD1304982, TP53I3, tumor protein p53 inducible protein 3, Tumor protein p53-inducible protein 3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
289138, 9540
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
B0BNC9, Q53FA7
Gene Symbols:
TP53I3
Immunogen:
Synthetic peptide, corresponding to amino acids 230-286 of Human PIG3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG