PIPA586455

MLH1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586455-Each-of-1 In Stock ₹ 44,705.10

PIPA586455 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MLH1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mlh1

Gene Alias

1110035C23Rik, AI317206, AI325952, AI561766, COCA2, colon cancer, nonpolyposis type 2, DNA mismatch repair protein Mlh1, DNA mismatch repair protein Mlh1-like protein, FCC2, hMLH1, HNPCC, HNPCC2, I79_014127, MGC5172, mismatch repair protein 1, MLH1, MLH-1, mutL homolog 1, mutL homolog 1 (E. coli), mutL homolog 1, colon cancer, nonpolyposis type 2, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), mutL protein homolog 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4292

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

P40692

Gene Symbols

Mlh1

Immunogen

Synthetic peptide, corresponding to amino acids 450-500 of Human MLH1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • MLH1 is a DNA mismatch repair protein
  • The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time
  • An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI)
  • These defects in DNA repair pathways have been related to human carcinogenesis
  • The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC)
  • MSHS2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process
  • It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.

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Show Difference

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Thermo Scientific

PIPA586455

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Antigen:
MLH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mlh1

Gene Alias:
1110035C23Rik, AI317206, AI325952, AI561766, COCA2, colon cancer, nonpolyposis type 2, DNA mismatch repair protein Mlh1, DNA mismatch repair protein Mlh1-like protein, FCC2, hMLH1, HNPCC, HNPCC2, I79_014127, MGC5172, mismatch repair protein 1, MLH1, MLH-1, mutL homolog 1, mutL homolog 1 (E. coli), mutL homolog 1, colon cancer, nonpolyposis type 2, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), mutL protein homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4292

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P40692

Gene Symbols:
Mlh1

Immunogen:
Synthetic peptide, corresponding to amino acids 450-500 of Human MLH1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586456

--


Antigen:
MSH6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MSH6

Gene Alias:
AU044881, AW550279, cb326, DNA mismatch repair protein Msh6, g/T mismatch-binding protein, GTBP, GTMBP, hMSH6, HNPCC5, HSAP, LOC100360342, mismatch repair protein Msh6, Msh6, mutS (E. coli) homolog 6, MutS alpha 160kDa subunit, mutS homolog 6, mutS homolog 6 (E. coli), MutS protein homolog 6, MutS-alpha 160 kDa subunit, MutS-alpha 160kDa subunit, p160, rCG61559-like, Sperm associated protein, sperm-associated protein, wu:fb36c12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17688, 2956

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P52701, P54276

Gene Symbols:
MSH6

Immunogen:
Synthetic peptide, corresponding to amino acids 350-400 of Human MSH6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA586460

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Antigen:
EphB6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPHB6

Gene Alias:
Cekl, chicken eph/elk receptor-like protein, EPB6, EPH receptor B6, EPHB6, EphB6v, Epherin B6, Epherin receptor B6, ephrin type A receptor, ephrin type-B receptor 6, HEP, human kinase-defective Eph-family receptor protein, MEP, MGC129910, MGC129911, Tyrosine-protein kinase-defective receptor EPH-6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13848, 2051, 312275

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O08644, O15197, P0C0K7

Gene Symbols:
EPHB6

Immunogen:
Synthetic peptide, corresponding to amino acids 851-900 of Human EphB6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA586462

--


Antigen:
UNG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ung

Gene Alias:
DGU, DKFZp781L1143, HIGM4, HIGM5, UDG, UNG, Ung1, UNG15, UNG2, unga, uracil DNA glycosylase, uracil DNA glycosylase a, uracil-DNA glycosylase, uracil-DNA glycosylase 1, uracil-DNA glycosylase 2, uracil-DNA glycosylase isoform UNG1, uracil-DNA glycosylase isoform UNG2, uracil-DNA glycosylase nuclear isoform, zgc:56102

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22256, 304577, 7374

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P13051, P97931

Gene Symbols:
Ung

Immunogen:
Synthetic peptide, corresponding to amino acids 200-240 of Human UDG.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG