PIPA586455

MLH1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586455-Each-of-1 In Stock ₹ 46,502.50

PIPA586455 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

MLH1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mlh1

Gene Alias

1110035C23Rik, AI317206, AI325952, AI561766, COCA2, colon cancer, nonpolyposis type 2, DNA mismatch repair protein Mlh1, DNA mismatch repair protein Mlh1-like protein, FCC2, hMLH1, HNPCC, HNPCC2, I79_014127, MGC5172, mismatch repair protein 1, MLH1, MLH-1, mutL homolog 1, mutL homolog 1 (E. coli), mutL homolog 1, colon cancer, nonpolyposis type 2, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), mutL protein homolog 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4292

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

P40692

Gene Symbols

Mlh1

Immunogen

Synthetic peptide, corresponding to amino acids 450-500 of Human MLH1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA586456

--

Img

Thermo Scientific

PIPA586017

--

Img

Thermo Scientific

PIPA586155

--

Img

Thermo Scientific

PIPA586600

--

Img

Thermo Scientific

PIPA586596

--

Img

Thermo Scientific

PIPA586616

--

Img

Thermo Scientific

PIPA586439

--

Img

Thermo Scientific

PIPA585941

--

Description

  • MLH1 is a DNA mismatch repair protein
  • The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time
  • An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI)
  • These defects in DNA repair pathways have been related to human carcinogenesis
  • The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC)
  • MSHS2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process
  • It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586455

--


Antigen:
MLH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mlh1

Gene Alias:
1110035C23Rik, AI317206, AI325952, AI561766, COCA2, colon cancer, nonpolyposis type 2, DNA mismatch repair protein Mlh1, DNA mismatch repair protein Mlh1-like protein, FCC2, hMLH1, HNPCC, HNPCC2, I79_014127, MGC5172, mismatch repair protein 1, MLH1, MLH-1, mutL homolog 1, mutL homolog 1 (E. coli), mutL homolog 1, colon cancer, nonpolyposis type 2, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), mutL protein homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4292

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P40692

Gene Symbols:
Mlh1

Immunogen:
Synthetic peptide, corresponding to amino acids 450-500 of Human MLH1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586456

--


Antigen:
MSH6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MSH6

Gene Alias:
AU044881, AW550279, cb326, DNA mismatch repair protein Msh6, g/T mismatch-binding protein, GTBP, GTMBP, hMSH6, HNPCC5, HSAP, LOC100360342, mismatch repair protein Msh6, Msh6, mutS (E. coli) homolog 6, MutS alpha 160kDa subunit, mutS homolog 6, mutS homolog 6 (E. coli), MutS protein homolog 6, MutS-alpha 160 kDa subunit, MutS-alpha 160kDa subunit, p160, rCG61559-like, Sperm associated protein, sperm-associated protein, wu:fb36c12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17688, 2956

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P52701, P54276

Gene Symbols:
MSH6

Immunogen:
Synthetic peptide, corresponding to amino acids 350-400 of Human MSH6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586460

--


Antigen:
EphB6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPHB6

Gene Alias:
Cekl, chicken eph/elk receptor-like protein, EPB6, EPH receptor B6, EPHB6, EphB6v, Epherin B6, Epherin receptor B6, ephrin type A receptor, ephrin type-B receptor 6, HEP, human kinase-defective Eph-family receptor protein, MEP, MGC129910, MGC129911, Tyrosine-protein kinase-defective receptor EPH-6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13848, 2051, 312275

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O08644, O15197, P0C0K7

Gene Symbols:
EPHB6

Immunogen:
Synthetic peptide, corresponding to amino acids 851-900 of Human EphB6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586462

--


Antigen:
UNG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ung

Gene Alias:
DGU, DKFZp781L1143, HIGM4, HIGM5, UDG, UNG, Ung1, UNG15, UNG2, unga, uracil DNA glycosylase, uracil DNA glycosylase a, uracil-DNA glycosylase, uracil-DNA glycosylase 1, uracil-DNA glycosylase 2, uracil-DNA glycosylase isoform UNG1, uracil-DNA glycosylase isoform UNG2, uracil-DNA glycosylase nuclear isoform, zgc:56102

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22256, 304577, 7374

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P13051, P97931

Gene Symbols:
Ung

Immunogen:
Synthetic peptide, corresponding to amino acids 200-240 of Human UDG.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG