PIPA586515

PUMA alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586515-Each-of-1 In Stock ₹ 44,705.10

PIPA586515 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PUMA alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BBC3

Gene Alias

BBC3, BCL2 binding component 3, Bcl-2 binding component 3, bcl-2-binding component 3, Bcl-2-binding component 3, isoforms 1/2, Bcl-2-binding component 3, isoforms 3/4, BH3-only, FLJ42994, JFY1, JFY-1, p53 up-regulated modulator of apoptosis, PUMA, PUMA/JFY1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

170770, 27113, 317673

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

Q80ZG6, Q96PG8, Q99ML1, Q9BXH1

Gene Symbols

BBC3

Immunogen

Synthetic peptide, corresponding to amino acids 132-183 of Human PUMA.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA586741

--

Img

Thermo Scientific

PIPA586758

--

Img

Thermo Scientific

PIPA586784

--

Img

Thermo Scientific

PIPA586160

--

Img

Thermo Scientific

PIPA586759

--

Img

Thermo Scientific

PIPA586718

--

Img

Thermo Scientific

PIPA586711

--

Img

Thermo Scientific

PIPA586690

--

Description

  • PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53
  • The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b
  • PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53
  • PUMA may be a direct mediator of p53-induced apoptosis
  • Antisense inhibition of PUMA expression reduced the apoptotic response to p53, and PUMA is likely to play a role in mediating p53-induced cell death through the cytochrome c/Apaf-1-dependent pathway.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586515

--


Antigen:
PUMA alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BBC3

Gene Alias:
BBC3, BCL2 binding component 3, Bcl-2 binding component 3, bcl-2-binding component 3, Bcl-2-binding component 3, isoforms 1/2, Bcl-2-binding component 3, isoforms 3/4, BH3-only, FLJ42994, JFY1, JFY-1, p53 up-regulated modulator of apoptosis, PUMA, PUMA/JFY1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170770, 27113, 317673

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q80ZG6, Q96PG8, Q99ML1, Q9BXH1

Gene Symbols:
BBC3

Immunogen:
Synthetic peptide, corresponding to amino acids 132-183 of Human PUMA.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586518

--


Antigen:
Cdc34

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDC34

Gene Alias:
(E3-independent) E2 ubiquitin-conjugating enzyme R1, AI327276, CDC34, cell division cycle 34, cell division cycle 34 homolog, E2 ubiquitin-conjugating enzyme R1, E2-CDC34, serine protease, UBC3, UBCH3, UBE2R1, ubiquitin carrier protein, ubiquitin conjugating enzyme E2 R1, ubiquitin-conjugating enzyme Cdc34, ubiquitin-conjugating enzyme E2 R1, Ubiquitin-conjugating enzyme E2-32 kDa complementing, ubiquitin-conjugating enzyme E2-CDC34, Ubiquitin-protein ligase R1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
216150, 299602, 997

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P49427, Q8CFI2

Gene Symbols:
CDC34

Immunogen:
Synthetic peptide, corresponding to amino acids 150-200 of Human Cdc34.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586519

--


Antigen:
Carbonic Anhydrase IX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CA9

Gene Alias:
Ca9, CA-9, CAIX, CA-IX, Car9, Carbonate dehydratase IX, carbonic anhydrase 9, Carbonic anhydrase IX, carbonic dehydratase, G250, Membrane antigen MN, membrane antigen MN homolog, MN, MN/CA9, P54 / 58N, P54/58N, pMW1, RCC-associated antigen G250, RCC-associated protein G250, renal cell carcinoma-associated antigen G250

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
230099, 313495, 768

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q16790, Q8VHB5

Gene Symbols:
CA9, Car9

Immunogen:
Synthetic peptide, corresponding to amino acids 50-104 of Human CA IX.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586523

--


Antigen:
AKT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKT1

Gene Alias:
Akt, Akt kinase, AKT serine/threonine kinase 1, Akt/PKB, akt1, AKT1 kinase, AKT1m, Akt1m protein, Akt1-PA, Akt1-PB, Akt1-PC, Akt1-PD, Akt1-PE, CAKT, C-AKT, CG4006, CG4006-PA, CG4006-PB, CG4006-PC, CG4006-PD, CG4006-PE, CWS6, dAkt, D-Akt, dAkt kinase, dAKT/dPKB, dAkt/PKB, DAKT1, DAKT1/PKB, Dmel\CG4006, Dmel_CG4006, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, l(3)04226, l(3)89Bq, murine thymoma viral (v-akt) oncogene homolog 1, pAkt, P-AKT, PKB, PKB alpha, PKB beta, PKB gamma, PKB/AKT, PKB/dAKT, PKBalpha, PKB-ALPHA, PKBG, PRKBA, protein kinase B, Protein kinase B alpha, protein kinase B-alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC protein kinase alpha RAC-PK alpha, RAC serine/threonine protein kinase, RAC serine/threonine-protein kinase, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RacPK, RAC-PK-alpha, RAC-PK-beta, RAC-PK-gamma, related to A and C kinases, related to PKA to PKC protein kinases, related to the A and C kinases, SD10374p, serine/threonine protein kinase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11651, 207, 24185

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P31749, P31750, P47196

Gene Symbols:
AKT1

Immunogen:
Synthetic peptide, corresponding to amino acids 100-150 of Human AKT1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG