PIPA586573

PAI1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586573-Each-of-1 In Stock ₹ 44,619.54

PIPA586573 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

PAI1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Serpine1

Gene Alias

Endothelial plasminogen activator inhibitor, nexin, plasminogen activator inhibitor type 1, PAI, PAI1, PAI-1, PAI1 protein, PAI1A, Pai1aa, Planh, Planh1, plas, plasminogen activator inhibitor, plasminogen activator inhibitor 1, plasminogen activator inhibitor I, plasminogen activator inhibitor, type I, plasminogen activator inhibitor-1, Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI), putative plasminogen activator inhibitor-1, RATPAI1A, serine (or cysteine) peptidase inhibitor, clade E, member 1, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, serine (or cysteine) proteinase inhibitor, clade E, member 1, serine (or cysteine) proteinase inhibitor, member 1, serpin E1, serpin family E member 1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, SERPINE1, SERPINE-1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18787, 24617, 5054

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide, pH 7.2

Gene Accession No.

P05121, P20961, P22777

Gene Symbols

Serpine1

Immunogen

Synthetic peptide, corresponding to amino acids 281-330 of Human PAI-1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PAI1 (plasminogen activator inhibitor 1) belongs to serine protease inhibitor superfamily, and is the principal inhibitor of tissue-type and urokinase-type plasminogen activators (tPA and uPA)
  • Platelets are the main source of the circulating PAI11, but it is synthesized and secreted by many tissue and cell types, including fibroblasts, smooth muscle cells, endothelial cells, hepatocytes, and inflammatory cells
  • Expression of PAI11 can be regulated at the transcriptional level by many factors including growth factors, cytokines, hormones, inflammatory factors, glucose or lipid metabolites, vascular tone regulating factors, chemicals, and other environmental or physical factors
  • PAI1 is present at increased levels in various disease states, and has been linked to an increased occurrence of thrombosis in obesity, thrombophilia and the metabolic syndrome
  • Defects in PAI-1 are characterized by abnormal bleeding
  • PAI1 mediates inhibition of fibrinolysis by inhibiting the activity of plasminogen activator, and may promote neuronal survival
  • Other defects in PAI1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency)
  • Alternatively spliced transcript variants encoding different isoforms of PAI1 have been found.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586573

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Antigen:
PAI1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Serpine1

Gene Alias:
Endothelial plasminogen activator inhibitor, nexin, plasminogen activator inhibitor type 1, PAI, PAI1, PAI-1, PAI1 protein, PAI1A, Pai1aa, Planh, Planh1, plas, plasminogen activator inhibitor, plasminogen activator inhibitor 1, plasminogen activator inhibitor I, plasminogen activator inhibitor, type I, plasminogen activator inhibitor-1, Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI), putative plasminogen activator inhibitor-1, RATPAI1A, serine (or cysteine) peptidase inhibitor, clade E, member 1, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, serine (or cysteine) proteinase inhibitor, clade E, member 1, serine (or cysteine) proteinase inhibitor, member 1, serpin E1, serpin family E member 1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, SERPINE1, SERPINE-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18787, 24617, 5054

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide, pH 7.2

Gene Accession No.:
P05121, P20961, P22777

Gene Symbols:
Serpine1

Immunogen:
Synthetic peptide, corresponding to amino acids 281-330 of Human PAI-1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586574

--


Antigen:
Cytokeratin 13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KRT13

Gene Alias:
47 kDa cytokeratin, CK13, CK-13, cytokeratin 13, cytokeratin-13, K13, K-13, Ka13, keratin 13, keratin 13, type I, keratin complex 1, acidic, gene 13, keratin, type I cytoskeletal 13, Keratin-13, Krt-1.13, Krt1-13, KRT13, krt13 {ECO:0000250, MGC161462, MGC3781, Type I keratin Ka13, UniProtKB:P13646}, WSN2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16663, 287699, 3860

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P08730, P13646, Q6IFV4

Gene Symbols:
KRT13

Immunogen:
Synthetic peptide, corresponding to amino acids 250-300 of Human Cytokeratin 13.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586575

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Antigen:
CD51

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITGAV

Gene Alias:
1110004F14Rik, 2610028E01Rik, alpha v integrin, antigen identified by monoclonal antibody L230, Cd51, CD61, D430040G12Rik, Dnmt3l-ps1 pseudogene, GP3A, GPIIIa, integrin alpha V, integrin alpha-V, Integrin alpha-V heavy chain, Integrin alpha-V light chain, integrin alphaVbeta3, integrin subunit alpha V, integrin, alpha V, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), ITGAV, ITGB3, MSK8, Vitronectin receptor, vitronectin receptor alpha polypeptide (VNRA), vitronectin receptor subunit alpha, VNR, VNRA, VTNR

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16410, 296456, 3685

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P06756, P43406

Gene Symbols:
ITGAV

Immunogen:
Synthetic peptide, corresponding to amino acids 771-820 of Human Integrin alphaV.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586579

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Antigen:
IGHA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGHA1

Gene Alias:
IgA1, IGHA1, IGHA2, immunoglobulin heavy constant alpha 1, immunoglobulin heavy constant alpha 2 (A2m marker)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3493

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P01876

Gene Symbols:
IGHA1

Immunogen:
Synthetic peptide, corresponding to amino acids 241-290 of Human IgA.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG