PIPA586615

Cortactin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586615-Each-of-1 In Stock ₹ 44,705.10

PIPA586615 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Cortactin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cttn

Gene Alias

1110020L01Rik, amplaxin, cortactin, Cttn, Cttnb, EMS1, ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate), FLJ34459, mammary tumor and squamous cell carcinoma associated (p80/85 src substrate), oncogene EMS1, Oncogene SRC8, Src substrate cortactin, src8, Unknown (protein for MGC:137923)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13043, 2017, 60465

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

Q14247, Q60598, Q66HL2

Gene Symbols

Cttn

Immunogen

Synthetic peptide, corresponding to amino acids 427-481 of Human Cortactin.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Cortactin (Cttn) is a ubiquitous actin-binding protein that was originally identified as a substrate for Src
  • It contributes to the organization of the actin cytoskeleton and cell shape
  • Cortactin also plays a role in the formation of lamellipodia and cell migration
  • It is accumulated in peripheral, actin-enriched structures of cells suggesting that cortactin facilitates actin network formation
  • Cortactin has four major domains of interest the N-terminal acidic (NTA) and tandem repeats domains and the C-terminal proline-rich and SH3 Domains
  • NTA associates with the Arp2/3 and WASP complex at F-actin branches
  • Cortactin is involved in promoting cell motility and invasion, including a critical role in invadopodia, actin rich-subcellular protrusions associated with degradation of the ECM by cancer cells
  • Cortactin is phosphorylated by src family kinases at Y421, Y466, and Y482 and S405 and S418 that are phosphorylated by Erk family kinases.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586615

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Antigen:
Cortactin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cttn

Gene Alias:
1110020L01Rik, amplaxin, cortactin, Cttn, Cttnb, EMS1, ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate), FLJ34459, mammary tumor and squamous cell carcinoma associated (p80/85 src substrate), oncogene EMS1, Oncogene SRC8, Src substrate cortactin, src8, Unknown (protein for MGC:137923)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13043, 2017, 60465

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q14247, Q60598, Q66HL2

Gene Symbols:
Cttn

Immunogen:
Synthetic peptide, corresponding to amino acids 427-481 of Human Cortactin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA586616

--


Antigen:
DAB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DAB1

Gene Alias:
AI956902, C630028C02Rik, Dab reelin signal transducer 1, Dab, reelin signal transducer, homolog 1, Dab, reelin signal transducer, homolog 1 (Drosophila), Dab1, DAB1, reelin adaptor protein, disabled 1, disabled homolog 1, RP23-356E21.1, scm, scr, scrambler, yot, yotari

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13131, 1600, 266729

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O75553, P97318, Q8CJH2

Gene Symbols:
DAB1

Immunogen:
Synthetic peptide, corresponding to amino acids 191-240 of Human Dab1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA586618

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Antigen:
GAP43

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GAP43

Gene Alias:
Axonal membrane protein GAP-43, B-50, Basp2, brain abundant, membrane attached signal protein 2, calmodulin-binding protein P-57, Gap43, GAP-43, growth accentuating protein 43, growth associated protein 43, growth-associated protein 43, MGC156666, nerve growth-related peptide GAP43, neural phosphoprotein B-50, Neuromodulin, neuron growth-associated protein 43, neuron protein F1, PP46, Protein F1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14432, 2596, 29423

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P06837, P07936, P17677

Gene Symbols:
GAP43

Immunogen:
Synthetic peptide, corresponding to the N-terminus of Human GAP43.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA586620

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Antigen:
CD61

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITGB3

Gene Alias:
antigen CD61, BDPLT16, BDPLT2, beta3 integrin, CD61, EGK_08849, glycoprotein GPIIIa, glycoprotein IIIa, GP3A, GPIIIa, GT, INGRB3, integrin beta 3, integrin beta 3 (Cd61), integrin beta-3, integrin beta-3 subunit, integrin subunit beta 3, integrin, beta 3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), ITGB3, platelet glycoprotein IIIa, platelet glycoprotein IIIa integrin subunit beta 3, platelet gpIIIa, platelet membrane glycoprotein IIIa

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16416, 29302, 3690

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O54890, P05106

Gene Symbols:
ITGB3

Immunogen:
Synthetic peptide, corresponding to amino acids 751-800 of Human Integrin beta3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG