PIPA586952

XBP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586952-Each-of-1 In Stock ₹ 50,822.64

PIPA586952 - Each of 1

₹ 50,822.64

In Stock

Quantity

1

Base Price: ₹ 50,822.64

GST (18%): ₹ 9,148.075

Total Price: ₹ 59,970.715

Antigen

XBP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Xbp1

Gene Alias

D11Ertd39e, Hepatocarcinogenesis-related transcription factor, HTF, OTTHUMP00000028682, Tax-responsive element-binding protein 5, tax-responsive element-binding protein 5 homolog, TREB5, TREB-5, X-box binding protein 1, X-box-binding protein 1, X-box-binding protein 1, cytoplasmic form, X-box-binding protein 1, luminal form, XBP1, XBP-1, XBP2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22433, 289754, 7494

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

O35426, P17861, Q9R1S4

Gene Symbols

Xbp1

Immunogen

Recombinant protein of human XBP1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • XBP1 encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box
  • This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter
  • It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator
  • It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1)
  • The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor
  • The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress
  • A pseudogene of XBP1 has been identified and localized to chromosome 5.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586952

--


Antigen:
XBP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Xbp1

Gene Alias:
D11Ertd39e, Hepatocarcinogenesis-related transcription factor, HTF, OTTHUMP00000028682, Tax-responsive element-binding protein 5, tax-responsive element-binding protein 5 homolog, TREB5, TREB-5, X-box binding protein 1, X-box-binding protein 1, X-box-binding protein 1, cytoplasmic form, X-box-binding protein 1, luminal form, XBP1, XBP-1, XBP2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22433, 289754, 7494

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O35426, P17861, Q9R1S4

Gene Symbols:
Xbp1

Immunogen:
Recombinant protein of human XBP1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586953

--


Antigen:
IGFBP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGFBP2

Gene Alias:
AI255832, BP2, BRL-BP, IBP2, IBP-2, IGF binding protein 2, IGF-binding protein 2, IGFBP, IGFBP2, IGFBP-2, IGF-BP53, ILGFBPA, Insulin like growth factor binding protein, insulin like growth factor binding protein 2, insulin-like growth factor binding protein 2, insulin-like growth factor binding protein 2, 36kDa, insulin-like growth factor-binding protein 2, mIGFBP-2, OTTHUMP00000207753

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16008, 25662, 3485

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P12843, P18065, P47877

Gene Symbols:
IGFBP2

Immunogen:
A synthetic peptide of human IGFBP2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586954

--


Antigen:
CD53

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cd53

Gene Alias:
AI323659, antigen MOX44 identified by monoclonal antibody MRC-OX44, Cd53, CD53 antigen, CD53 glycoprotein, CD53 molecule, CD53 tetraspan antigen, cell surface antigen, cell surface glycoprotein CD53, Leukocyte antigen MRC OX-44, leukocyte surface antigen CD53, MOX44, OX44, Ox-44, tetraspanin-25, transmembrane glycoprotein, TSPAN25, tspan-25

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12508, 963

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P19397, Q61451

Gene Symbols:
Cd53

Immunogen:
Recombinant protein of human CD53.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586959

--


Antigen:
NOTCH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOTCH2

Gene Alias:
AGS2, AI853703, HJCYS, hN2, Motch B, N2, N2ECD, N2ICD, Neurogenic locus notch homolog protein 2, notch 2, Notch 2 extracellular truncation, Notch 2 intracellular domain, notch gene homolog 2, Notch homolog 2, notch receptor 2, Notch2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18129, 4853

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O35516, Q04721

Gene Symbols:
NOTCH2

Immunogen:
Recombinant protein of human NOTCH2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG