PIPA587024

SHH Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587024-Each-of-1 In Stock ₹ 47,614.14

PIPA587024 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

SHH

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Shh

Gene Alias

9530036O11Rik, Dsh, fc83d08, hedgehog, hemimelic extra toes, Hhg1, HHG-1, HLP3, HPE3, Hx, Hxl3, M100081, MCOPCB5, morphogen, shh, Shh N-terminal processed signaling domains, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, shh.L, shha, ShhN, ShhNC, ShhNp, short digits, SMMCI, sonic hedgehog, sonic hedgehog a, sonic hedgehog homolog, sonic hedgehog L homeolog, sonic hedgehog protein, Sonic hedgehog protein 19 kDa product, Sonic hedgehog protein A, Sonic hedgehog protein A N-product, Sonic hedgehog protein N-product, sonic hedgehog signaling molecule, sonic hedgehog signaling molecule a, sonic-you, syu, TPT, TPTPS, vhh1, vhh-1, wu:fc83d08, XELAEV_18030676mg, Xhh, xshh, X-SHH

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29499, 6469

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

Q15465, Q63673

Gene Symbols

Shh

Immunogen

A synthetic peptide of human SHH.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Sonic Hedgehog (SHH), which is expressed only during embryogenesis, is instrumental in patterning the early embryo
  • It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites
  • Of three human proteins showing sequence and functional similarity to the Sonic Hedgehog protein of Drosophila, this protein is the most similar
  • The protein is made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing
  • More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo
  • Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres
  • HPE is manifested by facial deformities
  • In addition, it is thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA587024

--


Antigen:
SHH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Shh

Gene Alias:
9530036O11Rik, Dsh, fc83d08, hedgehog, hemimelic extra toes, Hhg1, HHG-1, HLP3, HPE3, Hx, Hxl3, M100081, MCOPCB5, morphogen, shh, Shh N-terminal processed signaling domains, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, shh.L, shha, ShhN, ShhNC, ShhNp, short digits, SMMCI, sonic hedgehog, sonic hedgehog a, sonic hedgehog homolog, sonic hedgehog L homeolog, sonic hedgehog protein, Sonic hedgehog protein 19 kDa product, Sonic hedgehog protein A, Sonic hedgehog protein A N-product, Sonic hedgehog protein N-product, sonic hedgehog signaling molecule, sonic hedgehog signaling molecule a, sonic-you, syu, TPT, TPTPS, vhh1, vhh-1, wu:fc83d08, XELAEV_18030676mg, Xhh, xshh, X-SHH

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29499, 6469

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q15465, Q63673

Gene Symbols:
Shh

Immunogen:
A synthetic peptide of human SHH.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587026

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Antigen:
Synaptotagmin 4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Syt4

Gene Alias:
HsT1192, KIAA1342, synaptotagmin 4, synaptotagmin IV, Synaptotagmin4, Synaptotagmin-4, Syt3, Syt4, SytIV

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20983, 64440, 6860

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P40749, P50232, Q9H2B2

Gene Symbols:
Syt4

Immunogen:
Recombinant protein of human SYT4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA587028

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Antigen:
TOP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Top1

Gene Alias:
Ab2-086, AI467334, D130064I21Rik, DNA topoisomerase 1, DNA topoisomerase I, RP3-511B24.2, TOP1, Top-1, TOPI, topoisomerase (DNA) I, type I DNA topoisomerase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21969, 7150

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P11387, Q04750

Gene Symbols:
Top1

Immunogen:
A synthetic peptide of human TOP1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA587029

--


Antigen:
IL17RB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL17RB

Gene Alias:
CRL4, cytokine receptor CRL4, cytokine receptor-like 4, ecotropic viral integration site 27, EVI27, IL-17 receptor B, IL-17 receptor homolog 1, IL-17B, IL-17B receptor, IL17BR, IL-17ER, Il17rb, IL-17RB, IL17RH1, IL-17Rh1, IL-20, interleukin 17 receptor B, interleukin 17 receptor homolog 1, interleukin 17B receptor, interleukin-17 receptor B, Interleukin-17B receptor, MGC138900, MGC138901, MGC5245, UNQ2501/PRO19612, ZCYTO7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
306247, 50905, 55540

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q9JIP3, Q9NRM6

Gene Symbols:
IL17RB

Immunogen:
Recombinant protein of human IL17RB.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG