PIPA587351
Perforin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587351-Each-of-1 | In Stock | ₹ 44,191.74 |
PIPA587351 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,191.74
GST (18%): ₹ 7,954.513
Total Price: ₹ 52,146.253
Antigen
Perforin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PRF1
Gene Alias
Cyta, Cytolysin, FLH2, HPLH2, lymphocyte pore forming protein, lymphocyte pore-forming protein, OMAK, OTTHUMP00000019759, P1, perforin 1, perforin 1 (pore forming protein), Perforin1, perforin-1, Pfn, PFN1, Pfp, PGFL, PIGF, PIGF-2, PLGF, pore forming protein, pore-forming protein, PRF1, Prf-1, PRF1 (pore forming protein 1), RATCYTA, RP11-710A11.3
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18646, 50669, 5551
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2.66 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P10820, P14222, P35763
Gene Symbols
PRF1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 280-555 of human Perforin (NP_0050322)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: EEKKKKHKMT ASFHQTYRER HSEVVGGHHT SINDLLFGIQ AGPEQYSAWV NSLPGSPGLV DYTLEPLHVL LDSQDPRREA LRRALSQYLT DRARWRDCSR PCPPGRQKSP RDPCQCVCHG SAVTTQDCCP RQRGLAQLEV TFIQAWGLWG DWFTATDAYV KLFFGGQELR TSTVWDNNNP IWSVRLDFGD VLLATGGPLR LQVWDQDSGR DDDLLGTCDQ APKSGSHEVR CNLNHGHLKF RYHARCLPHL GGGTCLDYVP QMLLGEPPGN RSGAVW; Positive Samples: Mouse thymus, Mouse kidney; Cellular Location: Cell membrane, Cytoplasmic granule lumen, Endosome lumen, Multi-pass membrane protein Perforin is one of the major cytolytic proteins of cytolytic granules
- Perforin is a cytolytic mediator and is stored in and released by cytoplasmic granules
- Moreover, perforin is involved in immune defense against tumors and virus infections as mediated by cytotoxic lymphocytes
- Perforin is a 555 amino acid protein with a 21 amino acid signal peptide, and has a molecular weight of 70 to 75 kD
- Perforin is a pore forming protein with a mechanism of transmembrane channel formation similar to C9, and homology between perforin and C9 have been demonstrated
- Studies show that perforin is expressed only in killer cell lines and not in helper T lymphocytes or other tumor cells tested
- Perforin is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis
- Defects in the perforin gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood
- Alternative splicing results in multiple transcript variants of perforin.
Compare Similar Items
Show Difference
Antigen: Perforin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PRF1
Gene Alias: Cyta, Cytolysin, FLH2, HPLH2, lymphocyte pore forming protein, lymphocyte pore-forming protein, OMAK, OTTHUMP00000019759, P1, perforin 1, perforin 1 (pore forming protein), Perforin1, perforin-1, Pfn, PFN1, Pfp, PGFL, PIGF, PIGF-2, PLGF, pore forming protein, pore-forming protein, PRF1, Prf-1, PRF1 (pore forming protein 1), RATCYTA, RP11-710A11.3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18646, 50669, 5551
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.66 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P10820, P14222, P35763
Gene Symbols: PRF1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 280-555 of human Perforin (NP_0050322)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Perforin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PRF1
Gene Alias:
Cyta, Cytolysin, FLH2, HPLH2, lymphocyte pore forming protein, lymphocyte pore-forming protein, OMAK, OTTHUMP00000019759, P1, perforin 1, perforin 1 (pore forming protein), Perforin1, perforin-1, Pfn, PFN1, Pfp, PGFL, PIGF, PIGF-2, PLGF, pore forming protein, pore-forming protein, PRF1, Prf-1, PRF1 (pore forming protein 1), RATCYTA, RP11-710A11.3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18646, 50669, 5551
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.66 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P10820, P14222, P35763
Gene Symbols:
PRF1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 280-555 of human Perforin (NP_0050322)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Calpastatin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cast
Gene Alias: BS-17, Calpain inhibitor, calpastatin, calpastatin isoform III, calpastatin precursor (EC 3.4.22.17), calpastatin type 1, calpastatin type 2, calpastatin type 3, calpastatin type I, calpastatin type II, calpastatin type III, calpastatin type IV, Cast, Erythrocyte calpastatin, heart calpastatin, PLACK, Sperm BS-17 component, type III calpastatin
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12380, 25403, 831
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.97 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P20810, P27321, P51125
Gene Symbols: Cast
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 596-695 of human CAST (NP_0011773711)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Calpastatin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cast
Gene Alias:
BS-17, Calpain inhibitor, calpastatin, calpastatin isoform III, calpastatin precursor (EC 3.4.22.17), calpastatin type 1, calpastatin type 2, calpastatin type 3, calpastatin type I, calpastatin type II, calpastatin type III, calpastatin type IV, Cast, Erythrocyte calpastatin, heart calpastatin, PLACK, Sperm BS-17 component, type III calpastatin
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12380, 25403, 831
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.97 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P20810, P27321, P51125
Gene Symbols:
Cast
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 596-695 of human CAST (NP_0011773711)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: GluR2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Gria2
Gene Alias: AMPA selective glutamate receptor, AMPA-selective glutamate receptor 2, GluA2, Glur2, GluR-2, GLURB, GluR-B, GluR-K2, glutamate ionotropic receptor AMPA type subunit 2, glutamate receptor, glutamate receptor 2, glutamate receptor B, glutamate receptor B flip isoform, glutamate receptor ionotropic, AMPA 2, glutamate receptor, ionotropic, AMPA 2, glutamate receptor, ionotropic, AMPA2 (alpha 2), GRIA2, HBGR2, OTTHUMP00000165324, OTTHUMP00000220942, OTTHUMP00000220943
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14800
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.52 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P23819
Gene Symbols: Gria2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-230 of human GluR2/GluR2/GRIA2 (NP_0010770881)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
GluR2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Gria2
Gene Alias:
AMPA selective glutamate receptor, AMPA-selective glutamate receptor 2, GluA2, Glur2, GluR-2, GLURB, GluR-B, GluR-K2, glutamate ionotropic receptor AMPA type subunit 2, glutamate receptor, glutamate receptor 2, glutamate receptor B, glutamate receptor B flip isoform, glutamate receptor ionotropic, AMPA 2, glutamate receptor, ionotropic, AMPA 2, glutamate receptor, ionotropic, AMPA2 (alpha 2), GRIA2, HBGR2, OTTHUMP00000165324, OTTHUMP00000220942, OTTHUMP00000220943
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14800
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.52 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P23819
Gene Symbols:
Gria2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-230 of human GluR2/GluR2/GRIA2 (NP_0010770881)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: LRP5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LRP5
Gene Alias: BMND1, EVR1, EVR4, HBM, HGNC:6697, LDL receptor related protein 5, low density lipoprotein receptor-related protein 5, low density lipoprotein receptor-related protein 7, low-density lipoprotein receptor-related protein 5, Low-density lipoprotein receptor-related protein 7, LR3, Lrp5, LRP-5, LRP7, LRP-7, mKIAA4142, OPPG, OPS, OPTA1, VBCH2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16973, 293649
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.69 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q91VN0
Gene Symbols: LRP5
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1400-1500 of human LRP5 (NP_0023262)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LRP5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LRP5
Gene Alias:
BMND1, EVR1, EVR4, HBM, HGNC:6697, LDL receptor related protein 5, low density lipoprotein receptor-related protein 5, low density lipoprotein receptor-related protein 7, low-density lipoprotein receptor-related protein 5, Low-density lipoprotein receptor-related protein 7, LR3, Lrp5, LRP-5, LRP7, LRP-7, mKIAA4142, OPPG, OPS, OPTA1, VBCH2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16973, 293649
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.69 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q91VN0
Gene Symbols:
LRP5
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1400-1500 of human LRP5 (NP_0023262)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat, Rat
Product Type:
Antibody
Isotype:
IgG