PIPA587456
eIF3a Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587456-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA587456 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
eIF3a
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EIF3A
Gene Alias
150/170, A830012B05Rik, Centrosomin, centrosomin homolog, Csma, cytoplasmic protein p167, Eif3, eIF3 p167, eIF3 p180, eIF3 p185, EIF3, p180 subunit, eIF3a, eIF3a {ECO:0000255, eIF3-p170, EIF3S10, eIF-3-theta, eIF3-theta, eIF-3-theta {ECO:0000255, eukaryotic translation initiation factor 3 subunit 10, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN), eukaryotic translation initiation factor 3 subunit 10 {ECO:0000255, eukaryotic translation initiation factor 3 subunit A, eukaryotic translation initiation factor 3 subunit A {ECO:0000255, eukaryotic translation initiation factor 3, subunit 10 (theta), eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD), eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD), eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa, eukaryotic translation initiation factor 3, subunit 10, 170kD, eukaryotic translation initi
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13669, 8661
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot, Western Blot
Concentration
0.68 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P23116, Q14152
Gene Symbols
EIF3A
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EIF3A (NP_0037411)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MPAYFQRPEN ALKRANEFLE VGKKQPALDV LYDVMKSKKH RTWQKIHEPI MLKYLELCVD LRKSHLAKEG LYQYKNICQQ VNIKSLEDVV RAYLKMAEEK TEAAKEESQQ MVLDIEDLDN IQTPESVLLS AVSGEDTQDR TDRLLLTPWV KFLWESYRQC LDLLRNNSRV ERLYHDIAQQ AFKFCLQYTR KAEFRKLCDN LRMHLSQIQR HHNQSTAINL NNPESQSMHL ETRLVQLDSA ISMELWQEAF; Positive Samples: HepG2, Jurkat, Mouse heart, Mouse ovary; Cellular Location: Cytoplasm RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773)
- The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC)
- The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition
- The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632, PubMed:11169732)
- The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773, PubMed:27462815)
- [UniProt]
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Antigen: eIF3a
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EIF3A
Gene Alias: 150/170, A830012B05Rik, Centrosomin, centrosomin homolog, Csma, cytoplasmic protein p167, Eif3, eIF3 p167, eIF3 p180, eIF3 p185, EIF3, p180 subunit, eIF3a, eIF3a {ECO:0000255, eIF3-p170, EIF3S10, eIF-3-theta, eIF3-theta, eIF-3-theta {ECO:0000255, eukaryotic translation initiation factor 3 subunit 10, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN), eukaryotic translation initiation factor 3 subunit 10 {ECO:0000255, eukaryotic translation initiation factor 3 subunit A, eukaryotic translation initiation factor 3 subunit A {ECO:0000255, eukaryotic translation initiation factor 3, subunit 10 (theta), eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD), eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD), eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa, eukaryotic translation initiation factor 3, subunit 10, 170kD, eukaryotic translation initi
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13669, 8661
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot, Western Blot
Concentration: 0.68 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P23116, Q14152
Gene Symbols: EIF3A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EIF3A (NP_0037411)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
eIF3a
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EIF3A
Gene Alias:
150/170, A830012B05Rik, Centrosomin, centrosomin homolog, Csma, cytoplasmic protein p167, Eif3, eIF3 p167, eIF3 p180, eIF3 p185, EIF3, p180 subunit, eIF3a, eIF3a {ECO:0000255, eIF3-p170, EIF3S10, eIF-3-theta, eIF3-theta, eIF-3-theta {ECO:0000255, eukaryotic translation initiation factor 3 subunit 10, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN), eukaryotic translation initiation factor 3 subunit 10 {ECO:0000255, eukaryotic translation initiation factor 3 subunit A, eukaryotic translation initiation factor 3 subunit A {ECO:0000255, eukaryotic translation initiation factor 3, subunit 10 (theta), eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD), eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD), eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa, eukaryotic translation initiation factor 3, subunit 10, 170kD, eukaryotic translation initi
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13669, 8661
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot, Western Blot
Concentration:
0.68 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P23116, Q14152
Gene Symbols:
EIF3A
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EIF3A (NP_0037411)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SMAD6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMAD6
Gene Alias: AOVD2, b2b390Clo, HsT17432, MAD homolog 6, mad homolog 7, Madh6, Madh7, Mothers against decapentaplegic homolog 6, mothers against decapentaplegic, drosophila, homolog of, 6, mothers against DPP homolog 6, Msmad6, SMAD, SMAD 6, SMAD family member 6, SMAD SMAD, SMAD, mothers against DPP homolog 6, SMAD6
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17130, 367100, 4091
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.33 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O35182, O43541
Gene Symbols: SMAD6
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 257-496 of human Smad6 (NP_0055763)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SMAD6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMAD6
Gene Alias:
AOVD2, b2b390Clo, HsT17432, MAD homolog 6, mad homolog 7, Madh6, Madh7, Mothers against decapentaplegic homolog 6, mothers against decapentaplegic, drosophila, homolog of, 6, mothers against DPP homolog 6, Msmad6, SMAD, SMAD 6, SMAD family member 6, SMAD SMAD, SMAD, mothers against DPP homolog 6, SMAD6
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17130, 367100, 4091
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.33 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O35182, O43541
Gene Symbols:
SMAD6
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 257-496 of human Smad6 (NP_0055763)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MAX
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAX
Gene Alias: AA960152, AI875693, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8, Class D basic helix-loop-helix protein 4, Delta-Max, Max, Max protein, MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, MYC associated factor X, myc-associated factor X, Myc-binding novel HLH/LZ protein, Myn, orf1, Protein max, protein myn
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4149
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.54 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P61244
Gene Symbols: MAX
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human MAX (NP_0023733)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MAX
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAX
Gene Alias:
AA960152, AI875693, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8, Class D basic helix-loop-helix protein 4, Delta-Max, Max, Max protein, MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, MYC associated factor X, myc-associated factor X, Myc-binding novel HLH/LZ protein, Myn, orf1, Protein max, protein myn
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4149
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.54 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P61244
Gene Symbols:
MAX
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human MAX (NP_0023733)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: EEA1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EEA1
Gene Alias: A430109M19Rik, B230358H09Rik, Early endosome antigen 1, early endosome antigen 1, 162kD, early endosome-associated protein, EEA1, Endosome-associated protein p162, MST105, MSTP105, ZFYVE2, Zinc finger FYVE domain-containing protein 2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 216238, 314764, 8411
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.13 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q15075, Q8BL66
Gene Symbols: EEA1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1182-1411 of human EEA1 (NP_0035572)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
EEA1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EEA1
Gene Alias:
A430109M19Rik, B230358H09Rik, Early endosome antigen 1, early endosome antigen 1, 162kD, early endosome-associated protein, EEA1, Endosome-associated protein p162, MST105, MSTP105, ZFYVE2, Zinc finger FYVE domain-containing protein 2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
216238, 314764, 8411
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.13 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q15075, Q8BL66
Gene Symbols:
EEA1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1182-1411 of human EEA1 (NP_0035572)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG