PIPA587473

SPHK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587473-Each-of-1 In Stock ₹ 44,619.54

PIPA587473 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

SPHK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPHK1

Gene Alias

1110006G24Rik, Acetyltransferase SPHK1, RP23-193A16.4, SK 1, Sk1, SKase, Sphingosine kinase 1, SPHK, SPHK1, SPK, SPK 1, Spk1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20698, 8877

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

2.37 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

Q8CI15, Q9NYA1

Gene Symbols

SPHK1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 50-384 of human SPHK1 (NP_0011360741)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: TLMLTERRNH ARELVRSEEL GRWDALVVMS GDGLMHEVVN GLMERPDWET AIQKPLCSLP AGSGNALAAS LNHYAGYEQV TNEDLLTNCT LLLCRRLLSP MNLLSLHTAS GLRLFSVLSL AWGFIADVDL ESEKYRRLGE MRFTLGTFLR LAALRTYRGR LAYLPVGRVG SKTPASPVVV QQGPVDAHLV PLEEPVPSHW TVVPDEDFVL VLALLHSHLG SEMFAAPMGR CAAGVMHLFY VRAGVSRAML LRLFLAMEKG RHMEYECPYL VYVPVVAFRL EPKDGKGVFA VDGELMVSEA VQGQVHPNYF WMVSGCVEPP PSWKPQQMPP PEEPL; Positive Samples: HeLa, Mouse kidney; Cellular Location: Cell membrane, Cytoplasm, Nucleus SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P)
  • S1P signals through G-protein coupled receptors and controls diverse cellular processes
  • Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer
  • SPHK1 catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions
  • Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine
  • S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis
  • The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA587473

--


Antigen:
SPHK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPHK1

Gene Alias:
1110006G24Rik, Acetyltransferase SPHK1, RP23-193A16.4, SK 1, Sk1, SKase, Sphingosine kinase 1, SPHK, SPHK1, SPK, SPK 1, Spk1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20698, 8877

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.37 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q8CI15, Q9NYA1

Gene Symbols:
SPHK1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-384 of human SPHK1 (NP_0011360741)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587474

--


Antigen:
S100B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
S100B

Gene Alias:
AI850290, Bpb, hypothetical protein LOC525716, NEF, protein S100-B, S100, S100 calcium binding protein B, S100 calcium binding protein beta (neural), S100 calcium-binding protein B, S100 calcium-binding protein beta (neural), S-100 calcium-binding protein beta subunit, S100 calcium-binding protein, beta (neural), S-100 calcium-binding protein, beta chain, S100 protein beta chain, S-100 protein beta chain, S-100 protein subunit beta, S100 protein, beta polypeptide, S100 protein, beta polypeptide, neural, S100B, S100-B, S100beta, S100P

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20203, 25742, 6285

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P04271, P04631, P50114

Gene Symbols:
S100B

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100B (NP_0062631)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587475

--


Antigen:
ACVR1C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ACVR1C

Gene Alias:
activin A receptor type 1C, activin A receptor type IC, activin A receptor, type IC, activin receptor type IC, Activin receptor type-1C, activin receptor-like kinase 7, ACTRI, ACTR-IC, ACVR1A, acvr1c, acvr1c {ECO:0000312, ACVRLK2, ACVRLK7, ALK2, Alk7, ALK-7, C230097P10, EMBL:AAC52803.1}, FOP, habrec1, SKR1, TGF-beta type 1 receptor, TSRI

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
130399, 245921, 269275

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.76 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P70539, Q8K348, Q8NER5

Gene Symbols:
ACVR1C

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-113 of human ACVR1C (NP_6603022)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587476

--


Antigen:
FAIM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FAIM

Gene Alias:
Faim, FAIM 1, FAIM1, Fas apoptotic inhibitory molecule, fas apoptotic inhibitory molecule 1, rFAIM

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55179

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.77 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q9NVQ4

Gene Symbols:
FAIM

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human FAIM (NP_0606171)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG