PIPA587759

USP13 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587759-Each-of-1 In Stock ₹ 44,705.10

PIPA587759 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

USP13

Classification

Polyclonal

Conjugate

Unconjugated

Gene

USP13

Gene Alias

2700071E21Rik, AI848077, Deubiquitinating enzyme 13, Isopeptidase T-3, ISOT3, IsoT-3, Ubiquitin carboxyl-terminal hydrolase 13, ubiquitin specific peptidase 13, ubiquitin specific peptidase 13 (isopeptidase T-3), ubiquitin specific protease 13 (isopeptidase T-3), Ubiquitin thioesterase 13, ubiquitin thiolesterase 13, ubiquitin-specific-processing protease 13, usp13, wu:fc61g08

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

310306, 72607

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.44 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

Q5BKP2

Gene Symbols

USP13

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 90-200 of human USP13 (NP_0039312)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MHLKRHVREK VRGASGGALP KRRNSKIFLD LDTDDDLNSD DYEYEDEAKL VIFPDHYEIA LPNIEELPAL VTIACDAVLS SKSPYRKQDP DTWENELPVS KYANNLTQLD N; Positive Samples: Mouse heart, Mouse brain, Rat heart, Rat brain Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum-associated degradation (ERAD)
  • Component of a regulatory loop that controls autophagy and p53/TP53 levels: mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes
  • Also deubiquitinates USP10, an essential regulator of p53/TP53 stability
  • In turn, PIK3C3/VPS34-containing complexes regulate USP13 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13
  • Recruited by nuclear UFD1 and mediates deubiquitination of SKP2, thereby regulating endoplasmic reticulum-associated degradation (ERAD)
  • Also regulates ERAD through the deubiquitination of UBL4A a component of the BAG6/BAT3 complex
  • Mediates stabilization of SIAH2 independently of deubiquitinase activity: binds ubiquitinated SIAH2 and acts by impairing SIAH2 autoubiquitination
  • Has a weak deubiquitinase activity in vitro and preferentially cleaves 'Lys-63'-linked polyubiquitin chains
  • In contrast to USP5, it is not able to mediate unanchored polyubiquitin disassembly
  • Able to cleave ISG15 in vitro; however, additional experiments are required to confirm such data
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA587759

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Antigen:
USP13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
USP13

Gene Alias:
2700071E21Rik, AI848077, Deubiquitinating enzyme 13, Isopeptidase T-3, ISOT3, IsoT-3, Ubiquitin carboxyl-terminal hydrolase 13, ubiquitin specific peptidase 13, ubiquitin specific peptidase 13 (isopeptidase T-3), ubiquitin specific protease 13 (isopeptidase T-3), Ubiquitin thioesterase 13, ubiquitin thiolesterase 13, ubiquitin-specific-processing protease 13, usp13, wu:fc61g08

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
310306, 72607

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.44 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q5BKP2

Gene Symbols:
USP13

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 90-200 of human USP13 (NP_0039312)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA587760

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Antigen:
NMI

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NMI

Gene Alias:
N-mcy (and STAT) interactor, Nmi, N-myc (and STAT) interactor, N-myc and STAT interactor, N-myc interactor, N-myc-interactor

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9111

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.44 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q13287

Gene Symbols:
NMI

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-307 of human NMI (NP_0046792)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA587765

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Antigen:
FADS2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fads2

Gene Alias:
2900042M13Rik, Acyl-CoA 6-desaturase, D6D, delta(6) desaturase, delta(6) fatty acid desaturase, delta-6 desaturase, delta-6 fatty acid desaturase, delta-6-desaturase, DES6, FADS2, Fadsd2, FADSD6, Fatty acid desaturase 2, linoleoyl-CoA desaturase (delta-6-desaturase)-like 2, LLCDL2, SLL0262, TU13

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56473, 83512, 9415

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.85 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
O95864, Q9Z0R9, Q9Z122

Gene Symbols:
Fads2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-131 of human FADS2 (NP_004256.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA587766

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Antigen:
ADAMTS2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Adamts2

Gene Alias:
a disintegrin and metalloproteinase, A disintegrin and metalloproteinase with thrombospondin motifs 2, a disintegrin and metalloproteinase with thrombospondin repeats, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2, ADAM, ADAM metallopeptidase with thrombospondin type 1 motif 2, ADAM metallopeptidase with thrombospondin type 1 motif, 2, ADAMs, ADAM-TS 2, ADAMTS2, ADAM-TS2, ADAMTS-2, ADAMTS-3, hPCPNI, metalloendopeptidases, mKIAA4060, NPI, PC I-NP, PCINP, PCI-NP, PCPNI, PNPI, Procollagen I N-proteinase, procollagen I/II amino propeptide-processing enzyme, Procollagen N-endopeptidase, procollagen N-proteinase, RGD1565950

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
287899, 9509

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.88 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O95450

Gene Symbols:
Adamts2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1029-1213 of human ADAMTS2 (O95450)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat, Rat

Product Type:
Antibody

Isotype:
IgG