PIPA587961
SIGLEC8 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587961-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA587961 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
SIGLEC8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SIGLEC8
Gene Alias
CDw329, MGC59785, SAF2, SAF-2, sialic acid binding Ig like lectin 8, sialic acid binding Ig-like lectin 8, sialic acid-binding Ig-like lectin 8, Sialoadhesin family member 2, Siglec, SIGLEC8, Siglec-8, SIGLEC8L
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
27181, 292846
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
2.23 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q9NYZ4
Gene Symbols
SIGLEC8
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 17-363 of human Siglec-8 (NP_0552572)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MEGDRQYGDG YLLQVQELVT VQEGLCVHVP CSFSYPQDGW TDSDPVHGYW FRAGDRPYQD APVATNNPDR EVQAETQGRF QLLGDIWSND CSLSIRDARK RDKGSYFFRL ERGSMKWSYK SQLNYKTKQL SVFVTALTHR PDILILGTLE SGHSRNLTCS VPWACKQGTP PMISWIGASV SSPGPTTARS SVLTLTPKPQ DHGTSLTCQV TLPGTGVTTT STVRLDVSYP PWNLTMTVFQ GDATASTALG NGSSLSVLEG QSLRLVCAVN SNPPARLSWT RGSLTLCPSR SSNPGLLELP RVHVRDEGEF TCRAQNAQGS QHISLSLSLQ NEGTGTSRPV SQVTLAA; Positive Samples: HL-60, 293T, Mouse liver, Rat blood; Cellular Location: Membrane, Single-pass type I membrane protein SIGLEC8 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells
- It preferentially binds to alpha2,3-linked sialic acid
- and also binds to alpha2,6-linked sialic acid
- The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface
- SIGLEC8 is expressed specifically on eosinophils
- The protein contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM)
- This motif is involved in downmodulation of cellular responses
- The phosphorylated ITIM motif binds to the SH2 domain of PTPN6/SHP-1
- The SIGLEC8 gene belongs to the immunoglobulin superfamily.
Compare Similar Items
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Antigen: SIGLEC8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SIGLEC8
Gene Alias: CDw329, MGC59785, SAF2, SAF-2, sialic acid binding Ig like lectin 8, sialic acid binding Ig-like lectin 8, sialic acid-binding Ig-like lectin 8, Sialoadhesin family member 2, Siglec, SIGLEC8, Siglec-8, SIGLEC8L
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27181, 292846
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.23 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q9NYZ4
Gene Symbols: SIGLEC8
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-363 of human Siglec-8 (NP_0552572)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SIGLEC8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SIGLEC8
Gene Alias:
CDw329, MGC59785, SAF2, SAF-2, sialic acid binding Ig like lectin 8, sialic acid binding Ig-like lectin 8, sialic acid-binding Ig-like lectin 8, Sialoadhesin family member 2, Siglec, SIGLEC8, Siglec-8, SIGLEC8L
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27181, 292846
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.23 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q9NYZ4
Gene Symbols:
SIGLEC8
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 17-363 of human Siglec-8 (NP_0552572)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: LRP8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LRP8
Gene Alias: 4932703M08Rik, AA921429, AI848122, ApoE receptor 2, APOER2, Apolipoprotein E receptor 2, HSZ75190, LDL receptor related protein 8, low density lipoprotein receptor relative, 8 ligand binding repeats, brain, low density lipoprotein receptor-related protein 8, apolipoprotein e receptor, low-density lipoprotein receptor-related protein 8, Lr8b, Lrp8, LRP-8, MCI1, Protein LR8B
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 362558, 7804
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.58 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q14114
Gene Symbols: LRP8
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 900 to the C-terminus of human ApoER2/ApoER2/LRP8 (NP_0046222)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LRP8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LRP8
Gene Alias:
4932703M08Rik, AA921429, AI848122, ApoE receptor 2, APOER2, Apolipoprotein E receptor 2, HSZ75190, LDL receptor related protein 8, low density lipoprotein receptor relative, 8 ligand binding repeats, brain, low density lipoprotein receptor-related protein 8, apolipoprotein e receptor, low-density lipoprotein receptor-related protein 8, Lr8b, Lrp8, LRP-8, MCI1, Protein LR8B
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
362558, 7804
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.58 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q14114
Gene Symbols:
LRP8
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 900 to the C-terminus of human ApoER2/ApoER2/LRP8 (NP_0046222)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: BCKDHB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Bckdhb
Gene Alias: 2-oxoisovalerate dehydrogenase beta subunit, 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial, BCKD BCKDH E1-beta, BCKDE1B, BCKDH E1-beta, BCKDHB, branched chain alpha-ketoacid dehydrogenase E1-beta subunit, branched chain keto acid dehydrogenase E1 beta, branched chain keto acid dehydrogenase E1 subunit beta, branched chain keto acid dehydrogenase E1, beta polypeptide, branched chain ketoacid dehydrogenase E1, beta polypeptide, branched-chain alpha-keto acid dehydrogenase E1 component beta chain, dJ279A18.1, E1B, E1b-beta subunit of the branched-chain complex, testis secretory sperm-binding protein Li 240mP
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12040, 29711
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.7 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P35738, Q6P3A8
Gene Symbols: Bckdhb
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 183-392 of human BCKDHB (NP_8988711)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
BCKDHB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Bckdhb
Gene Alias:
2-oxoisovalerate dehydrogenase beta subunit, 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial, BCKD BCKDH E1-beta, BCKDE1B, BCKDH E1-beta, BCKDHB, branched chain alpha-ketoacid dehydrogenase E1-beta subunit, branched chain keto acid dehydrogenase E1 beta, branched chain keto acid dehydrogenase E1 subunit beta, branched chain keto acid dehydrogenase E1, beta polypeptide, branched chain ketoacid dehydrogenase E1, beta polypeptide, branched-chain alpha-keto acid dehydrogenase E1 component beta chain, dJ279A18.1, E1B, E1b-beta subunit of the branched-chain complex, testis secretory sperm-binding protein Li 240mP
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12040, 29711
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.7 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P35738, Q6P3A8
Gene Symbols:
Bckdhb
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 183-392 of human BCKDHB (NP_8988711)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: P4HA1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: P4HA1
Gene Alias: 4-PH alpha-1, AL022634, collagen prolyl 4-hydroxylase alpha(I), C-P4Halpha(I), P4ha, P4ha1, PHalphaI, procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide, procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I, procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1, prolyl 4-hydroxylase alpha subunit, prolyl 4-hydroxylase subunit alpha 1, prolyl 4-hydroxylase subunit alpha-1, prolyl 4-hydroxylase, alpha polypeptide I
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18451, 5033, 64475
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.02 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P13674, P54001, Q60715
Gene Symbols: P4HA1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 235-534 of human P4HA1 (NP_0010179621)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
P4HA1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
P4HA1
Gene Alias:
4-PH alpha-1, AL022634, collagen prolyl 4-hydroxylase alpha(I), C-P4Halpha(I), P4ha, P4ha1, PHalphaI, procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide, procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I, procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1, prolyl 4-hydroxylase alpha subunit, prolyl 4-hydroxylase subunit alpha 1, prolyl 4-hydroxylase subunit alpha-1, prolyl 4-hydroxylase, alpha polypeptide I
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18451, 5033, 64475
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.02 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P13674, P54001, Q60715
Gene Symbols:
P4HA1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 235-534 of human P4HA1 (NP_0010179621)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG