PIPA587974

LGR5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587974-Each-of-1 In Stock ₹ 46,844.10

PIPA587974 - Each of 1

₹ 46,844.10

In Stock

Quantity

1

Base Price: ₹ 46,844.10

GST (18%): ₹ 8,431.938

Total Price: ₹ 55,276.038

Antigen

LGR5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Lgr5

Gene Alias

Fex, follicle expressed hormone, G protein-coupled receptor 49, GPR49, GPR67, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, GRP49, HG38, leucine rich repeat containing G protein coupled receptor 5, leucine rich repeat containing G protein-coupled receptor 5, leucine-rich repeat containing G protein-coupled receptor 5, leucine-rich repeat-containing G protein-coupled receptor 5, leucine-rich repeat-containing G-protein coupled receptor 5, Lgr5, orphan G protein-coupled receptor HG38, orphan G-protein coupled receptor FEX

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14160, 299802, 8549

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

2.92 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

D4AC13, O75473, Q9Z1P4

Gene Symbols

Lgr5

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 824-907 of human LGR5/GPR49 (NP_003658.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: NPHFKEDLVS LRKQTYVWTR SKHPSLMSIN SDDVEKQSCD STQALVTFTS SSITYDLPPS SVPSPAYPVT ESCHLSSVAF VPCL Positive Samples: HT-29, HepG2, SKOV3, A-431, Mouse brain, Rat brain; Cellular Location: Cell membrane, Golgi apparatus, Multi-pass membrane protein, trans-Golgi network membrane G protein-coupled receptor GPR49 has been reported to be expressed in brain, skeletal muscle, placenta, and spinal cord
  • ESTs have been isolated from normal human brain (amygdala), embryo, and placenta libraries and from human germ cell, uterus, and brain libraries
  • G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
  • All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
  • An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
  • Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
  • This &quoteturn-off&quote activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
  • Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA587974

--


Antigen:
LGR5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Lgr5

Gene Alias:
Fex, follicle expressed hormone, G protein-coupled receptor 49, GPR49, GPR67, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, GRP49, HG38, leucine rich repeat containing G protein coupled receptor 5, leucine rich repeat containing G protein-coupled receptor 5, leucine-rich repeat containing G protein-coupled receptor 5, leucine-rich repeat-containing G protein-coupled receptor 5, leucine-rich repeat-containing G-protein coupled receptor 5, Lgr5, orphan G protein-coupled receptor HG38, orphan G-protein coupled receptor FEX

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14160, 299802, 8549

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.92 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
D4AC13, O75473, Q9Z1P4

Gene Symbols:
Lgr5

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 824-907 of human LGR5/GPR49 (NP_003658.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587975

--


Antigen:
TRIM24

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIM24

Gene Alias:
A130082H20Rik, Ab2-427, AI447469, D430004I05Rik, E3 ubiquitin-protein ligase TRIM24, hTIF1, PTC6, RING finger protein 82, RING-type E3 ubiquitin transferase TIF1-alpha, RNF82, TF1A, Tif1, Tif1a, TIF1alpha, TIF1-alpha, Transcription intermediary factor 1-alpha, transcriptional intermediary factor 1, transcriptional intermediary factor 1, alpha, Trim24, tripartite motif containing 24, tripartite motif-containing 24, tripartite motif-containing protein 24

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8805

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.51 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
O15164

Gene Symbols:
TRIM24

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 600-820 of human TRIM24 (NP_0569892)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587976

--


Antigen:
PLOD3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLOD3

Gene Alias:
AI414586, bone protein I (BP-I), Galactosylhydroxylysine-glucosyltransferase, LH3, lysine hydroxylase 3, lysyl hydroxlase 3, lysyl hydroxylase 2, lysyl hydroxylase 3, Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3, Plod3, Procollagen galactosyltransferase, Procollagen glucosyltransferase, Procollagen glycosyltransferase, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3, procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26433, 8985

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.96 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O60568, Q9R0E1

Gene Symbols:
PLOD3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-280 of human PLOD3 (NP_0010751)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587977

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Antigen:
SLC16A3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC16A3

Gene Alias:
MCT 3, MCT 4, MCT3, MCT-3, Mct4, MCT-4, MGC138472, MGC138474, monocarboxylate transporter, monocarboxylate transporter 3, Monocarboxylate transporter 4, MOT4, Slc16a3, solute carrier family 16 (monocarboxylate transporter), member 3, solute carrier family 16 (monocarboxylic acid transporters), member 3, solute carrier family 16 member 3, solute carrier family 16, member 3 (monocarboxylic acid transporter 4)

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80878, 80879, 9123

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.64 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
O15427, O35910, P57787

Gene Symbols:
SLC16A3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 410-465 of human MCT4/SLC16A3 (NP_0041981)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG